Solar Coronal Structures and Stray Light in TRACE

Using the 2004 Venus transit of the Sun to constrain a semi-empirical point-spread function for the TRACE EUV solar telescope, we have measured the effect of stray light in that telescope. We find that 43% of 171A EUV light that enters TRACE is scattered, either through diffraction off the entrance filter grid or through other nonspecular effects. We carry this result forward, via known-PSF deconvolution of TRACE images, to identify its effect on analysis of TRACE data. Known-PSF deconvolution by this derived PSF greatly reduces the effect of visible haze in the TRACE 171A images, enhances bright features, and reveals that the smooth background component of the corona is considerably less bright (and hence much more rarefied) than commonly supposed. Deconvolution reveals that some prior conlclusions about the Sun appear to have been based on stray light in the images. In particular, the diffuse background "quiet corona" becomes consistent with hydrostatic support of the coronal plasma; feature contrast is greatly increased, possibly affecting derived parameters such as the form of the coronal heating function; and essentially all existing differential emission measure studies of small features appear to be affected by contamination from nearby features. We speculate on further implications of stray light for interpretation of EUV images from TRACE and similar instruments, and advocate deconvolution as a standard tool for image analysis with future instruments such as SDO/AIA.Comment: Accepted by APJ; v2 reformatted to single-column format for online readabilit

Bioaccumulation surveillance in Milford Haven Waterway

Biomonitoring of contaminants (metals, organotins, PAHs, PCBs) was carried out along the Milford Haven Waterway (MHW) and at a reference site in the Tywi Estuary during 2007-2008. The species used as bioindicators encompass a variety of uptake routes - Fucus vesiculosus (dissolved contaminants); Littorina littorea (grazer); Mytilus edulis and Cerastoderma edule (suspension feeders); and Nereis diversicolor (omnivore which often reflects contaminants in sediment). Differences in feeding strategy and habitat preference have subtle implications for bioaccumulation trends though, with few exceptions, contaminant body burdens in Milford Haven (MH) were higher than those at the Tywi reference site, reflecting inputs. Elevated concentrations of metals were occasionally observed at individual MH sites, whilst As and Se (molluscs and seaweed) were, for much of MHW, consistently at the higher end of the UK range. However, for the majority of metals, distributions in MH biota were not exceptional by UK standards. Several metal-species combinations indicated increases in bioavailability at upstream sites, which may reflect the influence of geogenic or other land-based sources – perhaps enhanced by lower salinity (greater proportions of more bioavailable forms). TBT levels in MH mussels were below OSPAR toxicity thresholds and in the Tywi were close to zero. Phenyltins were not accumulated appreciably in Mytilus, whereas some Nereis populations may have been subjected to localized (historical) sources. PAHs in Nereis tended to be evenly distributed across most sites, but with somewhat higher values at Dale for acenaphthene, fluoranthene, pyrene, benzo(a)anthracene and chrysene; naphthalenes tended to be enriched further upstream in the mid-upper Haven (a pattern seen in mussels for most PAHs). Whilst concentrations in MH mussels were mostly above reference site and OSPAR backgrounds, it is unlikely that ecotoxicological guidelines would be exceeded. PCBs in mussels were between upper and lower OSPAR guidelines and were unusual in their distribution in that highest levels occurred at the mouth of MH. Condition indices (CI) of bivalves (mussels and cockles) were highest at the Tywi reference site and at the seaward end of MH, decreasing upstream along the Waterway. There were a number of significant (negative) relationships between CI and body burdens and multivariate analysis indicated that a combination of contaminants could influence the pattern in condition (and sub-lethal responses such as MT and TOSC) across sites. Cause and effect needs to be tested more rigorously in future assessments

Using transfer entropy to study synaptic integration in Purkinje cells

Peer reviewe

Systematic review of antimicrobial drug prescribing in hospitals.

Prudent antibiotic prescribing to hospital inpatients has the potential to reduce the incidences of antimicrobial resistance and healthcare-associated infection. We reviewed the literature from January 1980 to November 2003 to identify rigorous evaluations of interventions to improve hospital antibiotic prescribing. We identified 66 studies with interpretable data of which 16 reported 20 microbiological outcomes: Gram negative resistant bacteria (GNRB), 10 studies; Clostridium difficile associated diarrhoea (CDAD), 5 studies; vancomycin resistant enterococci (VRE), 3 studies and methicillin resistant Staphylococcus aureus (MRSA), 2 studies. Four studies provide good evidence that the intervention changed microbial outcomes with low risk of alternative explanations, eight studies provide less convincing evidence and four studies were negative. The strongest and most consistent evidence was for CDAD but we were able to analyse only the immediate impact of interventions because of nonstandardised durations of follow up. The ability to compare results of studies could be substantially improved by standardising methodology and reporting

Generalized Integer Partitions, Tilings of Zonotopes and Lattices

In this paper, we study two kinds of combinatorial objects, generalized integer partitions and tilings of two dimensional zonotopes, using dynamical systems and order theory. We show that the sets of partitions ordered with a simple dynamics, have the distributive lattice structure. Likewise, we show that the set of tilings of zonotopes, ordered with a simple and classical dynamics, is the disjoint union of distributive lattices which we describe. We also discuss the special case of linear integer partitions, for which other dynamical systems exist. These results give a better understanding of the behaviour of tilings of zonotopes with flips and dynamical systems involving partitions.Comment: See http://www.liafa.jussieu.fr/~latapy

Are "EIT Waves" Fast-Mode MHD Waves?

We examine the nature of large-scale, coronal, propagating wave fronts (``EIT waves'') and find they are incongruous with solutions using fast-mode MHD plane-wave theory. Specifically, we consider the following properties: non-dispersive single pulse manifestions, observed velocities below the local Alfven speed, and different pulses which travel at any number of constant velocities, rather than at the ``predicted'' fast-mode speed. We discuss the possibility of a soliton-like explanation for these phenomena, and show how it is consistent with the above-mentioned aspects.Comment: to be published in the Astrophysical Journa

Podoconiosis in East and West Gojam Zones, Northern Ethiopia

Background: Podoconiosis is a neglected tropical disease (NTD) that is prevalent in red clay soil-covered highlands of tropical Africa, Central and South America, and northern India. It is estimated that up to one million cases exist in Ethiopia. This study aimed to estimate the prevalence of podoconiosis in East and West Gojam Zones of Amhara Region in northern Ethiopia. Methodology/Principal Findings: A cross-sectional household survey was conducted in Debre Eliyas and Dembecha woredas (districts) in East and West Gojam Zones, respectively. The survey covered all 17,553 households in 20 kebeles (administrative subunits) randomly selected from the two woredas. A detailed structured interview was conducted on 1,704 cases of podoconiosis identified in the survey. Results: The prevalence of podoconiosis in the population aged 15 years and above was found to be 3.3% (95% CI, 3.2% to 3.6%). 87% of cases were in the economically active age group (15–64 years). On average, patients sought treatment five years after the start of the leg swelling. Most subjects had second (42.7%) or third (36.1%) clinical stage disease, 97.9% had mossy lesions, and 53% had open wounds. On average, patients had five episodes of acute adenolymphangitis (ALA) per year and spent a total of 90 days per year with ALA. The median age of first use of shoes and socks were 22 and 23 years, respectively. More men than women owned more than one pair of shoes (61.1% vs. 50.5%; x2 = 11.6 p = 0.001). At the time of interview, 23.6% of the respondents were barefoot, of whom about two-thirds were women. Conclusions: This study showed high prevalence of podoconiosis and associated morbidities such as ALA, mossy lesions and open wounds in northern Ethiopia. Predominance of cases at early clinical stage of podoconiosis indicates the potential for reversing the swelling and calls for disease prevention interventions

Particle abundance in a thermal plasma: quantum kinetics vs. Boltzmann equation

We study the abundance of a particle species in a thermalized plasma by introducing a quantum kinetic description based on the non-equilibrium effective action. A stochastic interpretation of quantum kinetics in terms of a Langevin equation emerges naturally. We consider a particle species that is stable in the vacuum and interacts with \emph{heavier} particles that constitute a thermal bath in equilibrium and define of a fully renormalized single particle distribution function. The distribution function thermalizes on a time scale determined by the \emph{quasiparticle} relaxation rate. The equilibrium distribution function depends on the full spectral density and features off-shell contributions to the particle abundance. A model of a bosonic field $\Phi$ in interaction with two \emph{heavier} bosonic fields is studied. We find substantial departures from the Bose-Einstein result both in the high temperature and the low temperature but high momentum region. In the latter the abundance is exponentially suppressed but larger than the Bose-Einstein result. We obtain the Boltzmann equation in renormalized perturbation theory and highlight the origin of the differences. We argue that the corrections to the abundance of cold dark matter candidates are observationally negligible and that recombination erases any possible spectral distortions of the CMB. However we expect that the enhancement at high temperature may be important for baryogenesis.Comment: 39 pages, 11 figures. Clarifying remarks. To appear in Physical Review

Rossby adjustment over a step

The adjustment of a rotating fluid to a geostrophic equilibrium is now a classical problem in the theory of rotating fluids and is associated with the name of Rossby because of his pioneering work in this subject. The case of particular interest here is the one where the fluid is initially at rest but has a discontinuity in surface elevation along a certain line. If the bottom is flat, the adjustment gives rise to a jet flowing along the line of the initial discontinuity, the width of the jet being the Rossby radius of deformation. This paper examines how the flow is modified when the bottom is not flat, but has a step-like discontinuity running perpendicular to the line of the initial jump in surface elevation, giving rise to double Kelvin waves which propagate along the step. Flow is thus diverted parallel to the step, and behind the wave front there is no mass flux across the step.The effect of adding a vertical coast perpendicular to the step is also considered. When the double Kelvin wave propagates offshore, it leaves behind a state with no transport across the step. With propagation toward the coast, however, there is pinching of the longshore current into a narrow boundary layer.The problem is examined using (a) linear analysis, (b) laboratory experiments, and (c) numerical experiments