An investigation of the La Porte, Indiana, convective rainfall anomaly,

Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Meteorology, 1969.Bibliography: leaves 69-71.by Martin McCurdy Cassity, Jr.M.S

CONSCIENTIZATION THROUGH THE CONTEXT OF A BOOK CLUB: ADULTS’ EXPERIENCES OF CONSCIOUSNESS-RAISING

The purpose of this qualitative study is to understand the lived experiences of consciousness-raising for adults through the context of book clubs. Research about adult participation in book clubs remains scarce. Therefore, this study seeks to highlight how these contexts might promote adult learning and Conscientization

A Systematic Review of Music Therapy Practice and Outcomes with Acute Adult Psychiatric In-Patients

PMCID: PMC3732280This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Recovery from COVID-19 and Acute Respiratory Distress Syndrome: The Potential Role of an Intensive Care Unit Recovery Clinic: A Case Report

Background In this case report, we describe the trajectory of recovery of a young, healthy patient diagnosed with coronavirus disease 2019 who developed acute respiratory distress syndrome. The purpose of this case report is to highlight the potential role of intensive care unit recovery or follow-up clinics for patients surviving acute hospitalization for coronavirus disease 2019. Case Presentation Our patient was a 27-year-old Caucasian woman with a past medical history of asthma transferred from a community hospital to our medical intensive care unit for acute hypoxic respiratory failure due to bilateral pneumonia requiring mechanical ventilation (ratio of arterial oxygen partial pressure to fraction of inspired oxygen, 180). On day 2 of her intensive care unit admission, reverse transcription–polymerase chain reaction confirmed coronavirus disease 2019. Her clinical status gradually improved, and she was extubated on intensive care unit day 5. She had a negative test result for coronavirus disease 2019 twice with repeated reverse transcription–polymerase chain reaction before being discharged to home after 10 days in the intensive care unit. Two weeks after intensive care unit discharge, the patient returned to our outpatient intensive care unit recovery clinic. At follow-up, the patient endorsed significant fatigue and exhaustion with difficulty walking, minor issues with sleep disruption, and periods of memory loss. She scored 10/12 on the short performance physical battery, indicating good physical function. She did not have signs of anxiety, depression, or post-traumatic stress disorder through self-report questionnaires. Clinically, she was considered at low risk of developing post–intensive care syndrome, but she required follow-up services to assist in navigating the healthcare system, addressing remaining symptoms, and promoting return to her pre–coronavirus disease 2019 societal role. Conclusion We present this case report to suggest that patients surviving coronavirus disease 2019 with subsequent development of acute respiratory distress syndrome will require more intense intensive care unit recovery follow-up. Patients with a higher degree of acute illness who also have pre-existing comorbidities and those of older age who survive mechanical ventilation for coronavirus disease 2019 will require substantial post–intensive care unit care to mitigate and treat post–intensive care syndrome, promote reintegration into the community, and improve quality of life

Are sciences essential and humanities elective? Disentangling competing claims for humanities research public value

[EN] Recent policy discourse suggests that arts and humanities research is seen as being less useful to society than other disciplines, notably in science, technology, engineering and mathematics. The paper explores how this assumption s construction has been built and whether it is based upon an unfair prejudice: we argue for a prima facie case to answer in assuming that arts and humanities research s lower societal value. We identify a set of claims circulating in policy circles regarding science, technology, engineering and math- ematics research and arts and humanities research s differences. We find two groups: arts and humanities research is less useful than science, technology, engineering and mathematics, and arts and humanities research is merely differently useful. We argue that empirical analysis is necessary to disentangle which ones are true to assess whether policy-making is being based on rational and evidence-based claims. We argue that debates about public research value should recognise that humanities have different (but equally valid) kinds of societal value.This work was supported by the Spanish Ministry of Education, which funded the PhD research fellowship of Julia Olmos Peñuela through the F.P.U program [AP2007- 01850]. The research fellowship took place in the framework of the HERAVALUE project, Measuring the public value of arts and humanities research, financially supported by the HERA Joint Research Programme, cofunded by AHRC, AKA, DASTI, ETF, FNR, FWF, HAZU, IRCHSS, MHEST, NWO, RANNIS, RCN, VR and The European Community FP7 2007-2013, under the Socio-economic Sciences and Humanities programme. The authors would like to thank the editors and two anonymous referees for their invaluable comments. Any errors or omissions remain the authors’ responsibilitieOlmos-Peñuela, J.; Benneworth, P.; Castro-Martínez, E. (2015). Are sciences essential and humanities elective? Disentangling competing claims for humanities research public value. Arts and Humanities in Higher Education. 14(1):61-78. https://doi.org/10.1177/1474022214534081S617814

Synthesis of quaternary aryl phosphonium salts: photoredox-mediated phosphine arylation

We report a synthesis method for the construction of quaternary aryl phoshonium salts at ambient temperature. The regiospecific reaction invovles the coupling of phosphines with aryl radicals derived from diaryliodonium salts under photoredox conditions

Tixagevimab–cilgavimab for treatment of patients hospitalised with COVID-19: a randomised, double-blind, phase 3 trial

Background: Tixagevimab–cilgavimab is a neutralising monoclonal antibody combination hypothesised to improve outcomes for patients hospitalised with COVID-19. We aimed to compare tixagevimab–cilgavimab versus placebo, in patients receiving remdesivir and other standard care. Methods: In a randomised, double-blind, phase 3, placebo-controlled trial, adults with symptoms for up to 12 days and hospitalised for COVID-19 at 81 sites in the USA, Europe, Uganda, and Singapore were randomly assigned in a 1:1 ratio to receive intravenous tixagevimab 300 mg–cilgavimab 300 mg or placebo, in addition to remdesivir and other standard care. Patients were excluded if they had acute organ failure including receipt of invasive mechanical ventilation, extracorporeal membrane oxygenation, vasopressor therapy, mechanical circulatory support, or new renal replacement therapy. The study drug was prepared by an unmasked pharmacist; study participants, site study staff, investigators, and clinical providers were masked to study assignment. The primary outcome was time to sustained recovery up to day 90, defined as 14 consecutive days at home after hospital discharge, with co-primary analyses for the full cohort and for participants who were neutralising antibody-negative at baseline. Efficacy and safety analyses were done in the modified intention-to-treat population, defined as participants who received a complete or partial infusion of tixagevimab–cilgavimab or placebo. This study is registered with ClinicalTrials.gov, NCT04501978 and the participant follow-up is ongoing. Findings: From Feb 10 to Sept 30, 2021, 1455 patients were randomly assigned and 1417 in the primary modified intention-to-treat population were infused with tixagevimab–cilgavimab (n=710) or placebo (n=707). The estimated cumulative incidence of sustained recovery was 89% for tixagevimab–cilgavimab and 86% for placebo group participants at day 90 in the full cohort (recovery rate ratio [RRR] 1·08 [95% CI 0·97–1·20]; p=0·21). Results were similar in the seronegative subgroup (RRR 1·14 [0·97–1·34]; p=0·13). Mortality was lower in the tixagevimab–cilgavimab group (61 [9%]) versus placebo group (86 [12%]; hazard ratio [HR] 0·70 [95% CI 0·50–0·97]; p=0·032). The composite safety outcome occurred in 178 (25%) tixagevimab–cilgavimab and 212 (30%) placebo group participants (HR 0·83 [0·68–1·01]; p=0·059). Serious adverse events occurred in 34 (5%) participants in the tixagevimab–cilgavimab group and 38 (5%) in the placebo group. Interpretation: Among patients hospitalised with COVID-19 receiving remdesivir and other standard care, tixagevimab–cilgavimab did not improve the primary outcome of time to sustained recovery but was safe and mortality was lower. Funding: US National Institutes of Health (NIH) and Operation Warp Speed

Effects of sterilization on territory fidelity and maintenance, pair bonds, and survival rates of free-ranging coyotes

Predation on sheep by coyotes (Canis latrans) is a longstanding problem for sheep producers. Current research suggests that surgical sterilization of coyotes could prove to be an effective method of reducing their depredation rates on domestic sheep by modifying their predatory behavior. However, for sterilization to be a viable management tool, the territorial and affiliative behaviors of pack members would need to remain in place. We tested whether surgically sterilized coyotes maintained pair bonds and territories in the same manner as intact coyotes. We also examined if territory fidelity and survival rates differed between sterile and intact coyotes. From June 1997 to April 2000, 10 males and 9 females were sham-operated and radio-collared, while 20 males and 6 females were surgically sterilized and radio-collared. We monitored members of 5 sterile and 4 intact packs during 1998, 6 sterile and 7 intact packs during 1999, and 4 sterile and 6 intact packs through the 2000 breeding season. Behaviorally, sterile packs appeared to be no different than intact packs. A half-weight association index showed that social dyads within sterile coyote packs were located together as frequently as dyads within intact packs. Simultaneous radiolocations of members of sterile packs showed that members of sterile packs were significantly closer to each other than would be expected from random locations. There was no difference in size or degree of overlap between territories of sterile and sham-operated coyote packs. Sterile coyotes had a higher annual survival rate than reproductive animals in 2 of the 3 years, and there was no difference in the level of territory fidelity. We concluded that surgical sterilization did not modify the territorial or affiliative behaviors of free-ranging coyotes, and therefore sterile coyotes could be used as a management tool to exclude other potential sheep-killing coyotes

SURGICAL STERILIZATION AS A METHOD OF REDUCING COYOTE PREDATION ON DOMESTIC SHEEP

Predation by coyotes (Canis latrans) on domestic sheep is a problem for many livestock producers throughout the United States Intermountain West. We examined whether surgical sterilization of coyote packs would modify their predatory behavior and reduce predation rates on domestic sheep as compared to coyote packs with pups. From June 1997 to December 1997, we gathered baseline information on coyote pack size and movements. In winter 1998, we surgically sterilized and radio-collared members of 5 coyote packs. We also captured and radio-collared members of 6 packs that remained intact (i.e., reproductive). During summer 1998, only 1 sterile pack killed a lamb, while 3 intact packs killed 11 lambs. When only sheep-killing packs were included, sterile packs killed an average of 0.35 lambs/week, while intact packs killed 1.53 lambs/week in 1998. During winter 1999, we monitored 4 sterile and 8 intact packs. In summer 1999,3 sterile packs killed 3 lambs, while 4 intact packs killed 22 lambs. Considering only sheep-killing packs, sterile packs killed on average 0.38 lambs/week, while intact packs killed an average of 2.95 lambs/week in 1999. Coyotes were more likely to kill lambs that were on the edges of coyote territories as compared to core areas. Lambs of less than average weight were also more likely to be killed by coyotes. The available rodent biomass in each territory was not an influence on the differential kill rates exhibited between sterile and intact packs, nor did the amount of available alternate prey influence annual coyote predation rates on sheep. We conclude that we could use surgical sterilization to modify the predatory behavior of coyotes associated with pup production and provisioning of pups. Sterilization successfully reduced, but did not eliminate, coyote predation on domestic sheep. The amount of losses averted in the first year exceeded the costs associated with surgically sterilizing a coyote pack, which indicates that surgical sterilization could prove beneficial on small-scale livestock operations

Serologic Survey for Diseases in Free-Ranging Coyotes (\u3ci\u3eCanis latrans\u3c/i\u3e) from Two Ecologically Distinct Areas of Utah

The influence of habitat and associated prey assemblages on the prevalence of canine diseases in coyotes (Canis latrans) has received scant attention. From December 1997 through December 1999, we captured 67 coyotes in two ecologically distinct areas of Utah (USA): Deseret Land and Livestock Ranch and US Army Dugway Proving Ground. These areas differ in habitat and prey base. We collected blood samples and tested for evidence of various canine diseases. Prevalence of antibodies against canine parvovirus (CPV) was 100% in the Deseret population and 93% in the Dugway population. All juveniles in both populations had been exposed. We found no difference in the prevalence of antibodies against canine distemper virus (CDV) between the two populations (7% versus 12%; P=0.50). However, we did find an increase in antibodies with age in the Deseret population (P=0.03). Evidence of exposure to canine adenovirus (CAV) was found in both populations (52% and 72%; P=0.08). Prevalence of CAV antibodies was influenced by age on both areas (Deseret: P=0.003; Dugway: P=0.004). Antibodies to Francisella tularensis were low on both areas (2% and 4%). We found a significant difference (P=0.001) in the prevalence of exposure to Yersinia pestis between the two populations: 73% in Deseret compared to 11% in Dugway. This difference is most likely due to the prey species available in the two ecologically distinct study areas