MS-159: Robert Pomponio ’88 Theatre Arts Scrapbook

Robert Pomponio assembled this scrapbook while a student at Gettysburg College in the 1980’s. The scrapbook primarily focuses on the Owl & Nightingale Players production of “Happy End” by Bertolt Brecht and Kurt Weill, directed by Emile O. Schmidt in the spring of 1986. It includes production photographs taken by Pomponio, who was a member of the production crew, as well as captions and annotations provided by Pomponio. Also included in the scrapbook are photographs of campus events including performances by The Johnny White & Elite Band on November 1st, 1985, The DB’s in November 1985 and The Neats. Additional items in the scrapbook include photograph negatives for a trip to the Duke University Marine Lab September 28-29th 1986, a note written on February 14th, 1986 to Pomponio by classmate Susan Blume ‘87 regarding work he completed on a set, a program for the 91.1 WZBT radio station, a theatre arts program for scenes presented in Stevens Theatre on campus, the Prompter program for the production of “Happy End,” and a booklet including information for graduates May 14-15th 1988. This scrapbook and the commentary provided by Robert Pomponio provide a look into student life and popular culture of the 1980’s. Special Collections and College Archives Finding Aids are discovery tools used to describe and provide access to our holdings. Finding aids include historical and biographical information about each collection in addition to inventories of their content. More information about our collections can be found on our website http://www.gettysburg.edu/special_collections/collections/.https://cupola.gettysburg.edu/findingaidsall/1136/thumbnail.jp

MS-100: Reuel Williams Waters, 1st Battalion, Maine Light Artillery, 6th Maine Battery

This collection consists of three letters and a twenty-two page diary penned by Reuel Williams Waters. The letters are written by Waters to his sisters. Additionally, a photograph of Reuel Waters, several newspaper clippings concerning members of Waters’ family and reunions of the 6th Maine Battery, letters penned by Waters’ mother and sister-in-law after the war, and notes concerning Waters and Bentley (Waters’ wife Emily Bentley) family genealogy are included in this collection.https://cupola.gettysburg.edu/findingaidsall/1147/thumbnail.jp

MS-138: Emile O. Schmidt Collection

This collection represents an interesting variety of research materials in the area of theatre arts. The majority of the play books in Series I are from Owl & Nightingale productions directed by Emile Schmidt. Series II contains plays written by Emile Schmidt, and Series III consists of a costume sketch created by Emile Schmidt. Special Collections and College Archives Finding Aids are discovery tools used to describe and provide access to our holdings. Finding aids include historical and biographical information about each collection in addition to inventories of their content. More information about our collections can be found on our website http://www.gettysburg.edu/special_collections/collections/.https://cupola.gettysburg.edu/findingaidsall/1122/thumbnail.jp

MS-139: Jerome O. Hanson Collection

This collection consists of photograph slides of theatrical productions and projects produced at Gettysburg College and in the town of Gettysburg. The majority of this collection has been digitized and can be accessed upon request to Special Collections. Special Collections and College Archives Finding Aids are discovery tools used to describe and provide access to our holdings. Finding aids include historical and biographical information about each collection in addition to inventories of their content. More information about our collections can be found on our website http://www.gettysburg.edu/special_collections/collections/.https://cupola.gettysburg.edu/findingaidsall/1123/thumbnail.jp

MS-150: Battle of Gettysburg 150th Commemoration Collection

This collection contains physical items and documents as well as digital resources. It seeks to preserve the course and experience of the commemoration of the 150th Anniversary of the Battle of Gettysburg and other related historical events. The documents and publications contained within the collection not only record the many commemorative events that were held over a two-year period but also how those events progressed. Detailed coverage in the form of DVDs has been collected of many events, while the outline of many more has been captured through the compilation of their programs and other event information. Much of the official battle reenactment has been recorded in an extensive array of digital photographs, and the guides provided for and used by visitors demonstrate the resources available to assist in choosing which of the dazzling array of events to attend. The collection of artifacts and memorabilia serves as but a sample of the all that was available to the public to obtain from the commemoration, and thus offers a glimpse into how some may themselves remember the Sesquicentennial festivities in years to come. Special Collections and College Archives Finding Aids are discovery tools used to describe and provide access to our holdings. Finding aids include historical and biographical information about each collection in addition to inventories of their content. More information about our collections can be found on our website http://www.gettysburg.edu/special_collections/collections/.https://cupola.gettysburg.edu/findingaidsall/1128/thumbnail.jp

Striatal cholinergic interneurons generate beta and gamma oscillations in the corticostriatal circuit and produce motor deficits

Cortico-basal ganglia-thalamic (CBT) neural circuits are critical modulators of cognitive and motor function. When compromised, these circuits contribute to neurological and psychiatric disorders, such as Parkinson's disease (PD). In PD, motor deficits correlate with the emergence of exaggerated beta frequency (15-30 Hz) oscillations throughout the CBT network. However, little is known about how specific cell types within individual CBT brain regions support the generation, propagation, and interaction of oscillatory dynamics throughout the CBT circuit or how specific oscillatory dynamics are related to motor function. Here, we investigated the role of striatal cholinergic interneurons (SChIs) in generating beta and gamma oscillations in cortical-striatal circuits and in influencing movement behavior. We found that selective stimulation of SChIs via optogenetics in normal mice robustly and reversibly amplified beta and gamma oscillations that are supported by distinct mechanisms within striatal-cortical circuits. Whereas beta oscillations are supported robustly in the striatum and all layers of primary motor cortex (M1) through a muscarinic-receptor mediated mechanism, gamma oscillations are largely restricted to the striatum and the deeper layers of M1. Finally, SChI activation led to parkinsonian-like motor deficits in otherwise normal mice. These results highlight the important role of striatal cholinergic interneurons in supporting oscillations in the CBT network that are closely related to movement and parkinsonian motor symptoms.DP2 NS082126 - NINDS NIH HHS; R01 NS081716 - NINDS NIH HHS; R21 NS078660 - NINDS NIH HHShttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896681/Published versio

Metabarcoding of marine zooplankton: prospects, progress and pitfalls

Metabarcoding (large-scale taxonomic identification of complex samples via analysis of one or few orthologous DNA regions, called barcodes) is revolutionizing analysis of biodiversity of marine zooplankton assemblages. Metabarcoding relies on high-throughput DNA sequencing (HTS) technologies, which yield millions of DNA sequences in parallel and allow large-scale analysis of environmental samples. Metabarcoding studies of marine zooplankton have used various regions of nuclear small- (18S) and large-subunit (28S) rRNA, which allow accurate classification of novel sequences and reliable amplification with consensus primers, but- due to their relatively conserved nature- may underestimate species diversity in a community. To discriminate species, more variable genes are needed. A limited number of metabarcoding studies have used mitochondrial cytochrome oxidase I (COI), which ensures detection of species-level diversity, but may require group-specific primers and thus result in inconsistent amplification success rates. Reference databases with sequences for accurately-identified species are critically needed to allow taxonomic designation of molecular operational taxonomic units (MOTU) and comparison with previous studies of zooplankton diversity. Potential and promising applications of metabarcoding include rapid detection of impacts of climate change, monitoring and assessment of ecosystem health, calculation of biotic indices, characterization of food webs and detection of introduced, non-indigenous species

Do Trap-Neuter-Return (TNR) Practices Contribute to Human–Coyote Conflicts in Southern California?

One possible contributor to the unusually high number of conflicts between coyotes (Canis latrans) and people in urban southern California, USA, may be the abundance of free-roaming domestic cats (Felis catus; cats) subsidized by feeding and augmented by trap-neuter-return (TNR) programs. To determine if coyotes regularly prey on and consume cats, we combined visual and molecular-genetic approaches to identify prey items in stomachs of 311 coyotes from Los Angeles County and Orange County, provided to the South Coast Research and Extension Center, in Irvine, California, between June 2015 and December 2018. We detected cat remains in 35% of the stomachs of 245 coyotes with identifiable meals, making cats the most common mammalian prey item consumed and more common than reported previously. Using a geographic information systems approach, we then compared landscape characteristics associated with locations of coyotes that ate cats to public shelter records for TNR cat colonies. Cat-eating coyotes were associated with areas that were more intensively developed, had little natural or altered open space, and had higher building densities than coyotes that did not eat cats. Locations of TNR colonies had similar landscape characteristics. Coyotes associated with TNR colonies, and those that were euthanized (vs. road-killed), were also more likely to have consumed cats. The high frequency of cat remains in coyote diets and landscape characteristics associated with TNR colonies and cat-eating coyotes support the argument that high cat densities and associated supplemental feeding attracted coyotes. Effective mitigation of human–coyote conflicts may require prohibitions on outdoor feeding of free-roaming cats and wildlife and the elimination of TNR colonies

Defining the role of dexmedetomidine in the prevention of delirium in the intensive care unit (ICU)

Dexmedetomidine is a highly selective α2 agonist used as a sedative agent. It also provides anxiolysis and sympatholysis without significant respiratory compromise or delirium. We conducted a systematic review to examine whether sedation of patients in the intensive care unit (ICU) with dexmedetomidine was associated with a lower incidence of delirium as compared to other nondexmedetomidine sedation strategies. A search of PUBMED, EMBASE, and the Cochrane Database of Systematic Reviews yielded only three trials from 1966 through April 2015 that met our predefined inclusion criteria and assessed dexmedetomidine and outcomes of delirium as their primary endpoint. The studies varied in regard to population, comparator sedation regimen, delirium outcome measure, and dexmedetomidine dosing. All trials are limited by design issues that limit our ability definitively to conclude that dexmedetomidine prevents delirium. Evidence does suggest that dexmedetomidine may allow for avoidance of deep sedation and use of benzodiazepines, factors both observed to increase the risk for developing delirium. Our assessment of currently published literature highlights the need for ongoing research to better delineate the role of dexmedetomidine for delirium prevention

Marine Threats Overlap Key Foraging Habitat for Two Imperiled Sea Turtle Species in the Gulf of Mexico

Effective management of human activities affecting listed species requires understanding both threats and animal habitat-use patterns. However, the extent of spatial overlap between high-use foraging areas (where multiple marine species congregate) and anthropogenic threats is not well-known. Our modeling approach incorporates data on sea turtle spatial ecology and a suite of threats in the Gulf of Mexico to identify and map “hot spots” of threats to two imperiled turtle species. Of all 820 “high” threats grid cells, our tracked turtles foraged at least 1 day in 77% of them. Although threat data were not available outside the U.S. Exclusive Economic Zone, our map of turtle and threat “hot spots” can be incorporated in future more comprehensive threat analyses for the region. Knowledge of these shared foraging- and threat-areas can assist managers charged with designing effective conservation and population recovery strategies, in future habitat modeling efforts, and in designations of Gulf of Mexico habitat with high conservation value