14 research outputs found

    SARS-CoV-2 Infection Is at Herd Immunity in the Majority Segment of the Population of Qatar.

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    BACKGROUND: Qatar experienced a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic that disproportionately affected the craft and manual worker (CMW) population, who comprise 60% of the total population. This study aimed to assess ever and/or current infection prevalence in this population. METHODS: A cross-sectional population-based survey was conducted during July 26 to September 09, 2020, to assess both anti-SARS-CoV-2 positivity through serological testing and current infection positivity through polymerase chain reaction (PCR) testing. Associations with antibody and PCR positivity were identified through regression analyses. RESULTS: The study included 2641 participants, 69.3% of whom were <40 years of age. Anti-SARS-CoV-2 positivity was 55.3% (95% CI, 53.3%-57.3%) and was significantly associated with nationality, geographic location, educational attainment, occupation, and previous infection diagnosis. PCR positivity was 11.3% (95% CI, 9.9%-12.8%) and was significantly associated with nationality, geographic location, occupation, contact with an infected person, and reporting 2 or more symptoms. Infection positivity (antibody and/or PCR positive) was 60.6% (95% CI, 58.6%-62.5%). The proportion of antibody-positive CMWs who had a prior SARS-CoV-2 diagnosis was 9.3% (95% CI, 7.9%-11.0%). Only seven infections were ever severe, and only 1 was ever critical-an infection severity rate of 0.5% (95% CI, 0.2%-1.0%). CONCLUSIONS: Six in every 10 CMWs in Qatar have been infected, suggestive of reaching the herd immunity threshold. Infection severity was low, with only 1 in every 200 infections progressing to be severe or critical. Only 1 in every 10 infections had been previously diagnosed, which is suggestive of mostly asymptomatic or mild infections

    Functional fatigue of shape memory alloys

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    The book on Sustainable Automotive Technologies aims to draw special attention to the research and practice focused on new technologies and approaches capable of meeting the challenges to sustainable mobility. In particular, the book features incremental and radical technical advancements that are able to meet social, economic and environmental targets in both local and global contexts. These include original solutions to the problems of pollution and congestion, vehicle and public safety, sustainable vehicle design and manufacture, new structures and materials, new power-train technologies and vehicle concepts. In addition to vehicle technologies, the book is also concerned with the broader systemic issues such as sustainable supply chain systems, integrated logistics and telematics, and end-of-life vehicle management. It captures selected peer reviewed papers accepted for presentation at the 4th International Conference on Sustainable Automotive Technologies, ICSAT2012, held at the RMIT, Melbourne, Australia

    Adjuvant sildenafil therapy in poor responders undergoing in vitro fertilization: A prospective,

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    Objective: To evaluate the effect of adjuvant sildenafil on ovarian responsiveness in low responders undergoing IVF. Patient(s) and methods: Prospective randomized, double-blind, placebo controlled study was conducted at Obstetrics and Gynecology department, Tanta university hospital and Center of Assisted Reproduction, Om El-kora Hospital, Tanta, Egypt. Sixty patients were classified as low responders undergoing IVF. Supplementation with sildenafil (50 mg daily) or placebo to a gonadotropin releasing hormone antagonist protocol was provided. Result(s): There were no significant differences in total number of 75 IU FSH ampoules used (60.025 ± 5.52) versus (66.025 ± 4.51), the number of mature follicles recruited (3.35 ± 1.137) versus (2.95 ± .826), and the number of oocytes retrieved (3.95 ± 1.395) versus (3.65 ± 1.137) or cycle cancelation rates (26.7% in the treatment group versus 23.3% in placebo group). Conclusion: Adjuvant sildenafil does not enhance ovarian responsiveness in cases of previous low ovarian response to controlled ovarian hyperstimulation

    A Randomized Comparative Study between High-Intensity and Low-Level Laser Therapy in the Treatment of Chronic Nonspecific Low Back Pain

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    Objectives. Chronic nonspecific low back pain (chronic nsLBP) is one of the most common musculoskeletal disorders leading to disabilities and physical inactivity. Laser therapy was used in chronic nsLBP treatment; however, no previous studies have assessed the impacts of high-intensity laser therapy (HILT) versus low-level laser therapy (LLLT) on chronic nsLBP. This study compared the effects of HILT versus LLLT on individuals suffering from chronic nsLBP. Methods. The study was a randomized control trial. Sixty individuals with chronic nsLBP were enrolled in this study between May and November 2019. All participants were clinically diagnosed with chronic nsLBP. They were assigned randomly into three groups, 20 in each group. The first group received a program of LLLT, the second group received a program of HILT, and the third did not receive laser therapy (control group). Pain severity, disability, lumbar mobility, and quality of life were assessed before and after 12-week intervention. Results. Both LLLT and HILT groups showed a significant improvement of the Oswestry Disability Index (ODI), visual analogue scale (VAS), lumbar range of motion (ROM), and European Quality of Life (EuroQol) scores (p>0.05), while the control group did not show significant changes (p>0.05). Comparison among the three study groups postintervention showed significant differences in the outcome measures (p>0.05), while comparison between the LLLT and HILT groups showed nonsignificant differences (p>0.05). Conclusion. There are no different influences of LLLT versus HILT on chronic nsLBP patients. Both LLLT and HILT reduce pain and disability and improve lumbar mobility and quality of life in chronic nsLBP patients

    The burden of malaria in Sudan: incidence, mortality and disability – adjusted life – years

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    <p>Abstract</p> <p>Background</p> <p>Estimating the burden of malaria in Sudan is important for evidence-based planning of malaria control. Estimates of malaria burden in terms of DALYs (Disability Adjusted Life Years) were not developed locally. This study synthesized information from different sources to calculate malaria incidence, mortality and DALYs lost in Sudan in 2002.</p> <p>Methods</p> <p>A search for local studies and reports providing epidemiological data on malaria in Sudan was conducted. Preliminary estimates of incidence rate, case fatality rate and mortality rate were developed from the data found. The preliminary estimates were processed in the disease modelling computer software, DisMod II, to produce internally consistent mortality and incidence rates, which were used to calculate DALYs lost due to malaria.</p> <p>Results</p> <p>Malaria incidence in Sudan was estimated to be about 9 million episodes in 2002 and the number of deaths due to malaria was about 44,000. 2,877,000 DALYs were lost in Sudan in 2002 due to malaria mortality, episodes, anaemia and neurological sequelae. Children under five years of age had the highest burden. Males had the highest incidence and mortality, but females lost more DALYs.</p> <p>Conclusion</p> <p>Formal health system data underestimated malaria burden. The burden estimates can be useful in informing decision making, although uncertainty around them needs to be quantified. Epidemiological research is needed to fill data gaps and update the estimates.</p
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