Ultra-high-Q microcavity operation in H2O and D2O

Optical microcavities provide a possible method for boosting the detection sensitivity of biomolecules. Silica-based microcavities are important because they are readily functionalized, which enables unlabeled detection. While silica resonators have been characterized in air, nearly all molecular detections are performed in solution. Therefore, it is important to determine their performance limits in an aqueous environment. In this letter, planar microtoroid resonators are used to measure the relationship between quality factor and toroid diameter at wavelengths ranging from visible to near-IR in both H2O and D2O, and results are then compared to predictions of a numerical model. Quality factors (Q) in excess of 10^8, a factor of 100 higher than previous measurements in an aqueous environment, are observed in both H2O and D2O

Soft lithographic fabrication of microresonators

Using ultra-high-Q toroid microcavity masters, soft lithography is applied to fabricate polymer microcavity arrays with Q factors in excess of 10^6. This technique produces resonators with material-limited quality factors

Label-free, single molecule detection of cytokines using optical microcavities

Interleukin-2 (IL2) is a cytokine that regulates T-cell growth and is used in cancer therapies. By sensitizing a microcavity sensor surface with anti-IL2 and monitoring the resonant frequency, single molecules of IL2 can be detected

Electrical thermo-optic tuning of ultrahigh-Q microtoroid resonators

The ability to tune resonant frequency in optical microcavities is an essential feature for many applications. Integration of electrical-based tuning as part of the fabrication process has been a key advantage of planar microresonant devices. Until recently, the combination of these features has not been available in devices that operate in the ultrahigh-Q regime where device quality factors (Q) can exceed 100 million. In this letter, we demonstrate an electrically tunable resonator on a chip with ultrahigh-quality factors. Futhermore, the devices have demonstrated tuning rates in excess of 85 GHz/V2 and are capable of tuning more than 300 GHz

Ultra-high-Q toroid microcavities on a chip

We demonstrate microfabrication of ultra-high-Q microcavities on a chip, exhibiting a novel toroid-shaped geometry. The cavities possess Q-factors in excess of 100 million which constitutes an improvement close to 4 orders-of-magnitude in Q compared to previous work [B. Gayral, et al., 1999]

Fabrication and coupling to planar high-Q silica disk microcavities

Using standard lithographic techniques, we demonstrate fabrication of silica disk microcavities, which exhibit whispering-gallery-type modes having quality factors (Q) in excess of 1 million. Efficient coupling (high extinction at critical coupling and low, nonresonant insertion loss) to and from the disk structure is achieved by the use of tapered optical fibers. The observed high Q is attributed to the wedged-shaped edge of the disk microcavity, which is believed to isolate modes from the disk perimeter and thereby reduce scattering loss. The mode spectrum is measured and the influence of planar confinement on the mode structure is investigated. We analyze the use of these resonators for very low loss devices, such as add/drop filters

Ultralow-threshold microcavity Raman laser on a microelectronic chip

Using ultrahigh-Q toroid microcavities on a chip, we demonstrate a monolithic microcavity Raman laser. Cavity photon lifetimes in excess of 100 ns combined with mode volumes typically of less than 1000 µm^3 significantly reduce the threshold for stimulated Raman scattering. In conjunction with the high ideality of a tapered optical fiber coupling junction, stimulated Raman lasing is observed at an ultralow threshold (as low as 74 µW of fiber-launched power at 1550 nm) with high efficiency (up to 45% at the critical coupling point) in good agreement with theoretical modeling. Equally important, the wafer-scale nature of these devices should permit integration with other photonic, mechanical, or electrical functionality on a chip

Label-free detection of cytokines using optical microcavities

Ultra-high-Q microresonators have demonstrated sensitive and specific chemical and biological detection. The sensitivity is derived from the long photon lifetime inside the cavity and specificity is achieved through surface functionalization. Here, ultra-high-Q microcavities demonstrate label-free, single molecule detection of Interleukin-2 (IL-2) in fetal bovine serum (FBS). IL-2 is a cytokine released in response to immune system activation. The surface of the microtoroids was sensitized using anti-IL-2. The detection mechanism relies upon a thermo-optic mechanism to enhance resonant wavelength shifts induced through binding of a molecule

Chemical and biological detectors using ultra-high-Q microresonators

Recently, a method for fabricating planar arrays of optical microtoroid resonators with quality factors greater than 500 million was developed. These devices have previously demonstrated Raman and OPO lasing and radiation pressure induced oscillations. When immersed in an aqueous environment, these devices are able to maintain their ultra-high Q factors by operating in the visible wavelength band, enabling very sensitive chemical and biological detection. The fabrication and optical properties of these devices will be described. These devices have performed both chemical and biological detection. Systems which have been detected include D_2O in water and a variety of biological molecules. Sensitivity limits will also be discussed