260 research outputs found

    A firm-industry analysis of services versus manufacturing

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    [Abstract]: In the literature on the firm-industry debate to explain organizational performance the firm effect has been more supported than the industry effect by empirical studies, mainly focused on manufacturing firms and long time periods. Unfortunately, little attention has been paid to the service sector. In this paper we study separately manufacturing and services in a broad sample of Spanish companies. We observe that in manufacturing the firm effect outweighs the industry effect while in services the opposite is the case in a ten-year period. However, when we split the time horizon into two five-year sub-periods, this behavior only remains in the second one, of moderate economic growth. In the first one, of strong economic growth, the firm effect prevails for both manufacturing and services. These findings underline the importance of the industry effect for services, suggesting that such effect may have been underestimated in the literature, as well as that of the level of economic growth specially for the decision-making of practitioners

    Fracturas de húmero complicadas con lesión arterial

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    Presentamos una serie de 10 pacientes afectos de una fractura de húmero asociada a una lesión arterial, tratados entre Enero de 1990 y Octubre de 1993. Dentro de la serie distinguimos tres grupos, de acuerdo con la localización de la fractura (tercio proximal, diáfisis, región supracondílea). El análisis de los resultados sugiere que el peor pronóstico corresponde a las lesiones proximales y diafisarias por su etiología, daños asociados y menor posibilidad de circulación colateral de suplencia. El manejo de estas lesiones complejas exige un tratamiento quirúrgico interdisciplinario. Señalamos la utilidad de la fijación externa como método de osteosíntesis y el uso de un «shunt» provisional para perfundir el miembro durante la cirugía ósea. Se discute la indicación de arteriografía en los traumatismos agudos del miembro superior.A serie of 10 patients with a fracture of the humerus and associated arterial injury treated from January 1990 to October 1993 is reported. The serie was divided in 3 groups acording the proximal, mid shaft or supracondylar location of the fracture. Clinical results indicate a poor prognosis of proximal and mid shaft fractures related to their etiology, associated injuries and damage of the colateral vessels. The management of these complex injuries require an interdisciplinar approach. External fixation is an usefull stabilitation method for fractures associated with vascular damage. The utility of a temporary intraluminar vascular shunt to perfuse the limb at the bone surgery and preoperative arteriography are discussed

    Pseudoartrosis de escafoides carpiano tratadas mediante la técnica de Matti-Russe: estudio retrospectivo de 36 casos

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    Presentamos un estudio retrospectivo de una serie de 36 pacientes con pseudoartrosis de escafoides operados mediante la técnica de Matti-Russe entre 1985 y 1991. Utilizamos injerto córtico esponjoso obtenido del radio (50%), cresta ilíaca (42%) y cúbito (8%) sin diferencias en la incorporación. La tasa de curación fue mayor en las pseudoartrosis medias y distales (80%) que en las de localización proximal (54%). El 80% de los fracasos de curación en la localización media y distal eran pseudoartrosis de más de 30 meses de evolución. Los cambios degenerativos en el carpo de las pseudoartrosis no curadas fueron significativamente mayores (p< 0,001) que en las que se obtuvo la consolidación. La localización y la antiguedad de la pseudoartrosis parecen ser dos importantes factores pronósticos. La técnica de Matti-Russe presenta limitaciones en la pseudoartrosis de localización proximal y en los carpos muy degenerados.We reported a retrospective study of 36 patients with a pseudoarthrosis of the carpal scaphoid bone treated by the Matti-Russe operation from 1985 to 1991. We used radial (50%), iliac (42%) or ulnar (8%) autogenous grafts without any difference in the rate of incorporation. The rate of healing of the pseudoarthrosis was higher in mid and distal location (80%) than in proximal location (54%). In 80% of cases, healing failures in the mid and distal location occurred in old pseudoarthrosis ( >3 0 months evolution). Carpal degenerative changes were significantly higher (p < 0,01) in patients with not healed pseudoarthrosis. The location and the age of the pseudoarthrosis appear to be important prognostic factors. The Matti-Russe technique has limitations when is performed either in proximal pseudoarthrosis or in the presence of advanced radiocarpal osteoarthritis

    In silico scrutiny of genes revealing phylogenetic congruence with clinical prevalence or tropism properties of Chlamydia trachomatis strains

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    Microbes possess a multiplicity of virulence factors that confer them the ability to specifically infect distinct biological niches. Contrary to what is known for other bacteria, for the obligate intracellular human pathogen Chlamydia trachomatis, the knowledge of the molecular basis underlying serovars’ tissue specificity is scarce. We examined all ~900 genes to evaluate the association between individual phylogenies and cell-appetence or ecological success of C. trachomatis strains. Only ~1% of the genes presented a tree topology showing the segregation of all three disease groups (ocular, urogenital, and lymphatic) into three wellsupported clades. Approximately 28% of the genes, which include the majority of the genes encoding putative type III secretion system effectors and Inc proteins, present a phylogenetic tree where only lymphogranuloma venereum strains form a clade. Similarly, an exclusive phylogenetic segregation of the most prevalent genital serovars was observed for 61 proteins. Curiously, these serovars are phylogenetically cosegregated with the lymphogranuloma venereum serovars for ~20% of the genes. Some clade-specific pseudogenes were identified (novel findings include the conserved hypothetical protein CT037 and the predicted a-hemolysin CT473), suggesting their putative expendability for the infection of particular niches. Approximately 3.5% of the genes revealed a significant overrepresentation of nonsynonymous mutations, and the majority encode proteins that directly interact with the host. Overall, this in silico scrutiny of genes whose phylogeny is congruent with clinical prevalence or tissue specificity of C. trachomatis strains may constitute an important database of putative targets for future functional studies to evaluate their biological role in chlamydial infections.This work was supported by a grant, ERA-PTG/0004/2010, from Fundação para a Ciência e a Tecnologia (FCT) (to J.P.G.), in the frame of ERA-NET PathoGenoMics. A.N. is recipient of a FCT post-doctoral fellowship (SFRH/BPD/75295/2010), V.B. and R.F. are recipients of Ph.D. fellowships (SFRH/BD/68527/2010 and SFRH/BD/68532/2010, respectively) from FCT, and V.D. is a recipient of fellowship on behalf of the grant ERA-PTG/0004/2010

    Optimisation of processing routes for a marine biorefinery

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    13 páginas, 5 figurasCurrent fishing practices result in the waste of 20 million tonnes of valuable resources every year. However, from now on, vessels must keep on board and land both target and those non-target species subject to quota regulations, as regulated by recent EU legislation, in the reform of the Common Fisheries Policy (CFP). Therefore, an important quantity of low-value marine biomass has to be managed in an efficient manner to avoid its waste. Several added value products apart from fishmeal and oil (like enzymes or nutraceuticals) can be obtained from the wide variety of discarded species trough different valorisation processes. The challenge arises when these species can be handled by more than one processing route. The selection of the best alternatives has to fulfil often-opposite sustainability criteria, considering also the constraints associated to each resource and process. This was achieved by a multiobjective framework using a suitable and efficient optimization approach based on scatter-search. The results from the obtained Pareto fronts show that, in general, the valorisation of specific fish parts rather than the use of the whole specimen is more optimal from both points of view. It is also demonstrated that the most suitable products to be obtained are biopeptides, chondroitin sulphate and fish enzymes, due to their high sales price and relative low environmental impact. On the other hand, alternative technologies to present state-of-the-art ones should be considered for the production of chitin, gelatine and fishmeal due to their high environmental cost. Furthermore, a high number of the most optimal valorisation pathways leave biomass unprocessed and therefore, its treatment as solid waste must be included in the economic and environmental costsThe authors acknowledge the financial support received from the European Union through the LIFE Environment Program of the European Union (LIFE05 ENV/E000267-BE FAIR,LIFE08 ENV/E/000119-FAROS and LIFE13 ENV/ES/000131-LIFE iSEAS). Dr. Amaya Franco-Uría would like to thank Secretaría de Estado de Investigación, Desarrollo e Innovación for the support provided by the “Ramón y Cajal” SubprogramPeer reviewe

    Helping the family carers of Alzheimer's patients: from theory... to practice: a preliminary study

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    [Abstract] Alzheimer's disease (AD) represents one of the most important health issues in the western world. The ongoing care that the AD patient requires typically causes high stress levels, fatigue, irritation and depression in the caregiver, as well as socio-economical problems. The current study aimed to introduce a support program for carers of AD patients, in order to improve their quality of life. A Questionnaire for Carers and an Anxiety State Feature Questionnaire (STAI) was used to assess the carers. Results showed an overall improvement in the carers' health. Their subjective wellbeing increased, and though their situation had not changed, they nevertheless described feeling les s trapped. It can be concluded that possibly the mere fact that the carers feel that they have help available is enough to endorse the value of the program

    Developing a Compost Quality Index (CQI) based on the electrochemical quantification of Cd (HA) reactivity

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    The present work demonstrates the use of Cd2+ as a reactivity probe of the fulvic acids (FAs), humic acids (HAs) and dissolved organic matter (DOM) compost extracts. Significant differences were observed between the extracts, with the HA extract showing the highest reactivity. Comparing the different composts, the largest reactivity variation was again observed for HA then FA and finally DOM extracts. The Cd2+ binding extent was used to calculate the quality of composts and compared with a reference of uncomposted organic fertiliser (FLW), leading to the definition of an operational scale of compost quality. The parameter equivalent mass of fertiliser (mEF) was used for this scale sorted the seven composts from 0.353 to 1.09 kg FLW, for compost of sewage sludge (CSS) and vermicompost of domestic waste (CVDW), respectively. The significance of this parameter was verified through a correlation analysis between binding extent and the effect of compost application on lettuce crop growth in a field trial. The results demonstrate the potentiality of FA and HA extracts as markers of compost bioactivity and the use of Cd2+ as a reactivity probe.This work was financially supported by the Interreg VA Spain–Portugal Programme (EU) through the project Res2ValHum (0366_RES2VALHUM_1_P). A.C. Silva acknowledges receipt of a PhD grant (UMINHO/BD/40/2016) financed by the Operational Programme Norte 2020 (through the Project “NORTE-08-5369-FSE-000033”). J. Antelo and S. Fiol are also grateful for the financial support provided by Xunta de Galicia—Consellería de Educación e Ordenación Universitaria de Galicia (Consolidation of Competitive Groups of Research; GI-1245, ED431C 2022/40)

    A model structure-driven hierarchical decentralized stabilizing control structure for process networks

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    Based on the structure of process models a hierarchically structured state-space model has been proposed for process networks with controlled mass convection and constant physico-chemical properties. Using the theory of cascade-connected nonlinear systems and the properties of Metzler and Hurwitz matrices it is shown that process systems with controlled mass convection and without sources or with stabilizing linear source terms are globally asymptotically stable. The hierarchically structured model gives rise to a distributed controller structure that is in agreement with the traditional hierarchical process control system structure where local controllers are used for mass inventory control and coordinating controllers are used for optimizing the system dynamics. The proposed distributed controller is illustrated on a simple non-isotherm jacketed chemical reactor

    Comparison of cadmium binding by humic and fulvic acids extracted from compost samples of different feedstock

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    Compost is a bio-sustainable material produced by the controlled decomposition of the organic wastes. Composting can be employed for the urban organic waste treatment in alternative to incineration or landfill disposal [1]. The properties of compost are closely related to the presence of humic-like substances (HS). Both fulvic acids (FA) and humic acids (HA) contain a significant amount of carboxylic acids and phenolic groups that are responsible for some of their properties like solubility and ability to complex metal ions [2]. In the scope of the project Res2ValHum [3], composts produced from different feedstock were analysed and compared regarding the ability of the FA and the HA extracts to bind Cd2+. The free cadmium ion concentration was measured using the electroanalytical technique AGNES (absence of gradients and Nernstian equilibrium stripping) [4]. The cadmium binding by FA and HA extracts of two compost samples: compost of algae (CA) and compost of sludge sewage (CSS) is illustrated in Figure 1. Results indicate that the extent of the binding of cadmium by FA is similar despite the nature of the compost. In opposition, the HA extracts from the algae compost exhibit a larger capacity to bind cadmium ion in comparison to the extracted from the sludge sewage compost. These results indicate that the nature of the feedstock seem to affect more the structure of the HA (in comparison to the FA) formed during the composting process. The chemical characterization of these extracts by different analytical techniques are in course in order to fully understand the referred effect.0366_RES2VALHUM_1_P - Valorização de resíduos orgânicos: produção de substâncias húmicas, cofinanciada pelo Fundo Europeu de Desenvolvimento regional (FEDER) através do Programa INTERREG V-A Espanha-Portugal (POCTEP) 2014-202
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