208 research outputs found

    Lipidic cycle, condition factor and reproductive cell maturation in Gymnodactylus darwinii Gray, 1845 (Squamata, Phyllodactylidae) from a fragment of Atlantic Forest in northeastern Brazil

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    In this study, we describe a variation in fat bodies (liposomatic relationship), condition factor (the welfare degree of a population against the environment, K1), and male and female reproductive cells of the gecko Gymnodactylus darwinii (Gray, 1845) collected in two contiguous protected areas (Tapacurá and Mata do Camucim forests) in the municipality of São Lourenço da Mata, Pernambuco state, Brazil. We assessed seasonal variation and the influence of biotic (body temperature and K1 condition factor) and abiotic (air temperature and precipitation) factors on the lipidic cycle and reproductive cells’ maturation. As typical in geckos, fat bodies in G. darwinii decreased markedly during the high temperature and low precipitation periods. A slight variation in K1 suggests similar levels of energetic investment in growth and sexual maturation. Different reproductive cells matured similarly in sexually mature individuals, indicating a continuous, synchronised maturation cycle. Nonetheless, while fat bodies decreased and the number of mature reproductive cells increased in dry months, the opposite pattern was observed in rainy months. Our results indicate that G. darwinii does not show reproductive seasonality but instead peaks of reproductive activity (reproductive cell maturation, mating, lay eggs) synchronised in females and males, regulated by body temperature and climatic variables, including air temperature and precipitation.Asociación Herpetológica Argentin

    Development of an active orthosis prototype for lower limbs

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    ARAUJO, Márcio V. ; ALSINA, Pablo J. ; MEDEIROS, Adelardo A. D. ; PEREIRA, Jonathan P.P. ; DOMINGOS, Elber C. ; ARAÚJO, Fábio M.U. ; SILVA, Jáder S. . Development of an Active Orthosis Prototype for Lower Limbs. In: INTERNATIONAL CONGRESS OF MECHANICAL ENGINEERING, 20., 2009, Gramado, RS. Proceedings… Gramado, RS: [s. n.], 2009This paper presents the development of a prototype of an active orthosis for lower limbs. The proposed orthosis is an orthopedical device with the main objective of providing walking capacity to people with partial or total loss of limbs movements. In order to design the kinematics, dynamics and the mechanical characteristics of the prototype, the biomechanics of the human body was analized. The orthosis was projected to reproduce the movements of human gait. The movements of the joints of the orthosis are controlled by DC motors equipped with mechanical reductions, whose purpose is to reduce rotational speed and increase the torque, thus generating smooth movements. An embedded electronic system for sensory data acquisition and motor control was projected. The gait movements of the orthosis will be controlled by high level commands from a human-machine interface based on processings of electroencephalogram signals, speech recognition or joystic

    One-year timeline kinetics of cytokine-mediated cellular immunity in dogs vaccinated against visceral leishmaniasis

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    BACKGROUND: The main control strategy for visceral leishmaniasis in Brazil has been based on the elimination of seropositive dogs, although this is not widely accepted. In this context, the use of a long-lasting protective vaccine against canine visceral leishmaniasis (CVL) has been highly expected. The aim of this work was to determine the timeline kinetics of the cytokine microenvironment derived from circulating leukocytes as supportive immunological biomarkers triggered by Leishmune® vaccine. Cross-sectional kinetic analysis of cellular immunity cytokines was carried out at three times (1, 6 and 12 months) after primovaccination with Leishmune®. In vitro short-term whole blood cultures were stimulated with Leishmania infantum soluble antigen (SLAg). The secreted cytokine signatures and their major sources were determined. RESULTS: At six months after vaccination, Leishmune® induced an increase in IL-8, IFN-γ, IL-17a and TNF-α levels and a decrease in IL-10. Cytokine signature analysis revealed a shift in the microenvironment towards a pro-inflammatory profile mediated by IL-8 and IFN-γ. Both, CD4(+) (↑TNF-α(+) and ↑IFN-γ (+)) and CD8(+) (↑IL-17a and ↓IL-4) T-cells contributed to the acquired immune responses observed after stimulation with SLAg. CONCLUSIONS: The changes observed in the cytokine profile suggested that Leishmune® was able to induce an effective response at six months after primovaccination. After one year, it returned to baseline suggesting the need of additional boosting

    Lipidic cycle, condition factor and reproductive cell maturation in Gymnodactylus darwinii Gray, 1845 (Squamata, Phyllodactylidae) from a fragment of Atlantic Forest in northeastern Brazil

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    In this study, we describe a variation in fat bodies (liposomatic relationship), condition factor (the welfare degree of a population against the environment, K1), and male and female reproductive cells of the gecko Gymnodactylus darwinii (Gray, 1845) collected in two contiguous protected areas (Tapacurá and Mata do Camucim forests) in the municipality of São Lourenço da Mata, Pernambuco state, Brazil. We assessed seasonal variation and the influence of biotic (body temperature and K1 condition factor) and abiotic (air temperature and precipitation) factors on the lipidic cycle and reproductive cells’ maturation. As typical in geckos, fat bodies in G. darwinii decreased markedly during the high temperature and low precipitation periods. A slight variation in K1 suggests similar levels of energetic investment in growth and sexual maturation. Different reproductive cells matured similarly in sexually mature individuals, indicating a continuous, synchronised maturation cycle. Nonetheless, while fat bodies decreased and the number of mature reproductive cells increased in dry months, the opposite pattern was observed in rainy months. Our results indicate that G. darwinii does not show reproductive seasonality but instead peaks of reproductive activity (reproductive cell maturation, mating, lay eggs) synchronised in females and males, regulated by body temperature and climatic variables, including air temperature and precipitation.Asociación Herpetológica Argentin

    Federalism, ICT and development in the Global South

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    This paper builds on the ICT and development literature to answer the question on what indicators better represent ICT institutional background in the Global South, namely Central America, the Caribbean Islands, South America, Africa and South Asia. It delves into the institutional variable of federalism widely used in comparative analyzes tackling the correlation between e.g. broadband deployment and economic development, by finding granulated variables that portray a more precise scenario of institutional commensurability among countries being compared for public policy purposes. Its main underpinnings are the concept of information revolution and the methodology put forward by the Telecommunications Law Indicators for Comparative Studies (TLICS) Model. Six sets of federative indicators on revenue, fiscal transfer, regulatory jurisdiction, adjudication, planning, and media content regulation are put together to compare ICT federal environment in the Global South as a groundwork for the ICT comparative research. The empirical universe of the paper encompassed thirty-eight countries from Central and South America, the Caribbean Islands, Africa and South Asia, that form a potpourri of thirty officially unitary countries – Angola, Belize, Bolivia, Cabo Verde, Chile, Colombia, Costa Rica, Cuba, Dominican Republic, Ecuador, El Salvador, Guatemala, Guinea Bissau, Haiti, Honduras, Jamaica, Mozambique, New Zealand, Nicaragua, Panama, Papua New Guinea, Paraguay, Peru, Philippines, Sao Tome and Principe, Singapore, Suriname, Tanzania, Trinidad and Tobago, and Uruguay –, and eight federal countries – Argentina, Brazil, India, Malaysia, Mexico, Nigeria, South Africa, and Venezuela. The article is organized in three main parts. A brief description of the paper assumptions is performed in the first part. The second part applies TLICS variables to sets of the aforementioned states. The third part delves into the comparison of the states analyzed by means of categorizing the differences and commonalities revealed by more than one thousand five hundred variables collected in the legal and institutional framework of those countries and finally summarized in the ICT federal index (IFI) and ICT unitary index (IUI). We also test the association between federalism as the outcome and each of the independent (explanatory) variables proposed by the TLICS model by applying statistical tests (Fisher exact test, relative risk, and odds ratio). The only ICT variable significantly associated with a country being classified as a federal state is tax in the telecom and broadcast. As a main outcome, based on data collected from the institutional background and legal frameworks of those countries, we found clusters of federal commonalities in federal and unitary countries of the region. With that, we proposed two indices that better represent federal and unitary institutional backgrounds: The ICT Federal Index (IFI); and the ICT Unitary Index (IUI). They provide a real picture of their institutional background for ICT and development comparative purposes and gather sets of countries with similar institutional backgrounds upon which the ICT and Development literature may rely on to explain different outcomes from public policies or investments on ICT in countries that share a common institutional background, as far as the institutional variable of federalism is concerned

    Latex peptidases of Calotropis procera for dehairing of leather as an alternative to environmentally toxic sodium sulfide treatment

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    Dehairing of crude leather is a critical stage performed at the beginning of its processing to obtain industrially useful pieces. Tanneries traditionally apply a chemical process based on sodium sulfide. Since this chemical reactive is environmentally toxic and inefficiently recycled, innovative protocols for reducing or eliminating its use in leather depilation are welcomed. Therefore, latex peptidases from Calotropis procera (CpLP) and Cryptostegia grandiflora (CgLP) were assayed for this purpose. Enzyme activity on substrates representative of skin such as hide powder azure (UHPA), elastin (UE), azocollagen (UAZOCOL), keratin (UK), and epidermis (UEP) was determined, while depilation activity was assayed on cow hide. Only CpLP was active against keratin (13.4 UK) and only CgLP was active against elastin (0.12 UE). CpLP (93.0 UHPA, 403.6 UAZOCOL, 36.3 UEP) showed higher activity against the other substrates than CgLP (47.6 UHPA, 261.5 UAZOCOL, 8.5 UEP). In pilot assays, CpLP (0.05% w/v with sodium sulfite 0.6% w/v as activator) released hairs from cow hide pieces. Macroscopic and microscopic analyses of the hide revealed that the dehairing process was complete and the leather structure was preserved. The proteolytic system of C. procera is a suitable bioresources to be exploited by tanneries.Fil: Lopez, Laura Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Industrial. Centro de Investigación y Desarrollo del Cuero. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Centíficas. Centro de Investigación y Desarrollo del Cuero; ArgentinaFil: Viana, Carolina A.. Universidade Estadual Do Ceara; BrasilFil: Errasti, María Eugenia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Industrial. Centro de Investigación y Desarrollo del Cuero. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Centíficas. Centro de Investigación y Desarrollo del Cuero; ArgentinaFil: Garro, María Laura. Instituto Nacional de Tecnología Industrial. Centro de Investigación y Desarrollo del Cuero. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Centíficas. Centro de Investigación y Desarrollo del Cuero; ArgentinaFil: Martegani, José Eduardo. Instituto Nacional de Tecnología Industrial. Centro de Investigación y Desarrollo del Cuero. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Centíficas. Centro de Investigación y Desarrollo del Cuero; ArgentinaFil: Mazzilli, German Ariel. Instituto Nacional de Tecnología Industrial. Centro de Investigación y Desarrollo del Cuero. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Centíficas. Centro de Investigación y Desarrollo del Cuero; ArgentinaFil: Freitas, Cléverson D. T.. Universidade Estadual Do Ceara; BrasilFil: Araújo, Ídila M. S.. EMBRAPA Agrotropical; BrasilFil: da Silva, Rafaela O.. Universidade Estadual Do Ceara; BrasilFil: Ramos, Márcio V.. Universidade Estadual Do Ceara; Brasi

    Relação pescoço-coxa como índice antropométrico para diagnóstico da síndrome metabólica em universitários brasileiros: promoção da saúde e prevenção de enfermidades

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    Cartel presentado en el 3er Congreso Internacional de Comunicación en Salud (3ICHC), celebrado los días 19 y 20 de octubre de 2017 en la Universidad Carlos III de Madrid.O objetivo deste estudo é investigar a RPC como índice antropométrico para diagnóstico da Síndrome Metabólic
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