6 research outputs found

    The variability of the small cardiac vein in the adult human heart

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    Direct analyses were performed on 50 hearts submitted for post mortem examination. The remaining hearts were examined by the corrosion method. The aim of the work was to assess the morphology of the small cardiac vein. The small cardiac vein, which runs along the back surface of the coronary sulcus, would usually drain into the coronary sinus at its right side (86% of cases). Cases of the small cardiac vein draining into the middle cardiac vein were also noticed (12%) or directly into the right atrium (1%). In 1% of the preparations it ran along the right margin in the direction of the apex of the heart. In 30% of the corrosion preparations the small cardiac vein was not accessible with the help of corrosion. In 24% of the dissection preparations it was not possible to reach the small cardiac vein with the help of dissection. A statistically significant relationship was observed between the frequency of the presence or absence of the small cardiac vein and the sex of the donor (p > 0.001). In the group examined the percentage of men who did not have the small cardiac vein was 6 times higher than among the woman. There was no evidence for any statistically significant dependence between the frequency of occurrence or of absence of the small cardiac vein and the technique employed

    Anatomical eponyms — unloved names in medical terminology

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    Uniform international terminology is a fundamental issue of medicine. Names of various organs or structures have developed since early human history. The first proper anatomical books were written by Hippocrates, Aristotle and Galen. For this reason the modern terms originated from Latin or Greek. In a modern time the terminology was improved in particular by Vasalius, Fabricius and Harvey. Presently each known structure has internationally approved term that is explained in anatomical or histological terminology. However, some elements received eponyms, terms that incorporate the surname of the people that usually describe them for the first time or studied them (e.g., circle of Willis, follicle of Graff, fossa of Sylvious, foramen of Monro, Adamkiewicz artery). Literature and historical hero also influenced medical vocabulary (e.g. Achilles tendon and Atlas). According to various scientists, all the eponyms bring colour to medicine, embed medical traditions and culture to our history but lack accuracy, lead of confusion, and hamper scientific discussion. The current article presents a wide list of the anatomical eponyms with their proper anatomical term or description according to international anatomical terminology. However, since different eponyms are used in various countries, the list could be expanded

    Urinary bladder diverticulum as an unusual content of the inguinal canal

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    The inguinal urinary bladder hernia is a rare pathology observed mostly in males. A new case of asymptomatic reducible acquired inguinal hernia was revealed in a 54-year-old male during computed tomography (CT) undertaken for oncological follow-up. The right nephrectomy was previously performed due to clear cell carcinoma. The hernia was not visible on the CT 6 months before and on ultrasound performed after voiding. Slight herniation with a wide invagination of transversalis fascia but with empty bladder was seen on CT 4 months after the initial detection of hernia

    Effect of iodothyronine hormone status on doxorubicin related cardiotoxicity

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    The anthracycline anticancer agent doxorubicin has been recognised to induce a dose-dependent cardiotoxicity. The chronic form of such complication is characterized by an irreversible cardiac damage and congestive heart failure. Although the pathogenesis of anthracycline cardiotoxicity seems to be multifactorial, the pivotal role has been attributed to reactive oxygen species formation. Because redox equilibrium in cardiomyocytes may be regulated via iodothyronine hormones, the aim of the study was to appraise the effect of hypothyroidism on heart damages induced by doxorubicin. The rats received methimazole in drinking water (0.001 and 0.025%) after doxorubicin administration (2.0, 5.0 and 15 mg/kg). The cardiac morphology and blood biochemical markers of heart damage were assessed. Decreased levels of iodothyronine hormones had not significant impact on cardiac morphological changes and no effect on the level of B-type natriuretic peptide in rats receiving doxorubicin. Lower hormonal levels had sporadic, diverse effect on blood transaminases, lactate dehydrogenase and creatine kinase levels, but any relation to time, doxorubicin doses and hypothyroid status was found. Hypothyreosis leads to increase in fatty acid binding protein in rats receiving higher dose of doxorubicin. Hypothyreosis had no effect on heart stretching and on necrosis at morphological level, but caused biochemical symptoms of cardiomyocyte necrosis in rats receiving doxorubicin
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