Flow chart of the recruited population.

<p>*: Systemic Inflammatory Response Syndrome.</p

Representative example of EEG showing periodic discharges (PDs) in a septic ICU patient.

<p>See these spontaneous generalized repetitive discharges of spikes and bursts of sharp waves at nearly regular intervals and without evolution in location and morphology. Recording: 20 mm/sec, sensitivity: 10 μV/mm; filter settings: 0.500 Hz -70Hz.</p

Representative example of a non-reactive EEG following painful stimuli (pinching) in a septic ICU patient.

<p>No EEG background activity change was observed after the painful stimulation (pinching) Recording: 20 mm/sec, sensitivity: 10 μV/mm; filter settings: 0.500 Hz -70Hz.</p

Representative example of EEG showing the onset of an electrographic seizure (ESZ) in a septic ICU patient.

<p>See the onset of this spontaneous and sustained discharge of spikes and waves with changes in frequency and morphology. Recording: 20 mm/sec, sensitivity: 10 μV/mm; filter settings: 0.500 Hz -70Hz.</p

Prevalence of non-reactive EEG among different sub-groups of the studied septic ICU patients.

<p>Prevalence of non-reactive EEG among different sub-groups of the studied septic ICU patients.</p

Representative example of a reactive EEG following auditory stimulation (claps) in a septic ICU patient.

<p>See the diffuse and synchronic slowing of the EEG background activity, that appeared immediately after the auditory stimulation (claps). Recording: 20 mm/sec, sensitivity: 10 μV/mm; filter settings: 0.500 Hz -70Hz.</p

EEG findings and classification.

<p>EEG findings and classification.</p

Main characteristics at admission, inclusion and after hospital discharge.

<p><i>Abbreviations</i>: <i>n</i>: <i>number</i>, SAPSII: Simplified Acute Physiology Score; EEG: electroencephalogram; SIRS: Systemic Inflammatory Response Syndrome; RASS: Richmond Assessment Sedation Scale; SOFA: Sepsis-related Organ Failure Assessment; ICU: Intensive Care Unit;</p><p>*Only in sedated patients. Delirium was defined according to the CAM-ICU.</p><p>Main characteristics at admission, inclusion and after hospital discharge.</p

Scatter plots of Synek and Young EEG scales in the Delirium versus No-Delirium groups.

<p>Scatter plots of Synek and Young EEG scales in the Delirium versus No-Delirium groups.</p