Can I Show This Video?: Making Public Performance Rights Visible to Patrons

The Problem Faculty & students ask Research Assistance Desk (RAD) staff about showing videos in class or in group settings. Faculty also asked how to search for videos that had public performance rights. Since this information is in order records and/or buried in licenses RAD staff had to ask acquisitions staff if a specific video had PPR. The Goals Make PPR information readily available Make streaming videos with PPR searchabl

Are E-Book Packages Overwhelming and Redefining Your Collection?

Most academic libraries offer numerous e-books alongside their print titles. Traditionally, print materials have been chosen by subject liaisons with input from departmental faculty, whereas e-books have been acquired en masse through large collection purchases, subscriptions, or PDA/DDA programs that include large numbers of discovery records. At Kraemer Family Library, the print budget is divided into subject areas using a formula that includes the number of students in a discipline, level of program (bachelor, master, or doctorate), number of faculty by discipline, and average cost of materials in a subject area. This budget breakdown is an attempt to balance the library’s collection so that it reflects the focus and emphasis of the curriculum being taught on campus. Beginning in 2012, the Kraemer Family Library at the University of Colorado Colorado Springs began participating in two PDA/DDA e-book programs. The library also began purchasing e-book packages that were either publisher or subject based. During this same time, the library continued to use a formula to allocate the library’s print budget. Because e-books were not purchased according to any allocation, and the library was beginning a process of weeding the print collection, an analysis of the effect of e-books on the overall collection was undertaken. The purpose of this analysis was to determine what metrics should be used to determine the impact of e-books on the overall collection and to analyze that data for overall impact on the collection

Technicolor Theories with Negative S

We show that the pseudo Nambu--Goldstone boson contribution to the Peskin--Takeuchi electroweak parameter $S$ can be negative in a class of technicolor theories. This negative contribution can be large enough to cancel the positive techni-hadron contribution, showing that electroweak precision tests alone cannot be used to rule out technicolor as the mechanism of electroweak symmetry breaking.Comment: (LBL-32893, UCB-PTH 92/34, 10 pages; we added a discussion of uncertainties, fine-tuning, and SU(2) asymptotic freedom; the conclusions are unchanged.

Walking Technicolor And The ZbbˉZb\bar b Vertex

A slowly running technicolor coupling will affect the size of non-oblique corrections to the $Zb\bar b$ vertex from extended technicolor dynamics. We show that while ``walking technicolor'' reduces the magnitude of the corrections, they generally remain large enough to be seen at LEP.Comment: LaTeX, 11 pages, 3 figure

Cosmic Flows on 100 Mpc/h Scales: Standardized Minimum Variance Bulk Flow, Shear and Octupole Moments

The low order moments, such as the bulk flow and shear, of the large scale peculiar velocity field are sensitive probes of the matter density fluctuations on very large scales. In practice, however, peculiar velocity surveys are usually sparse and noisy, which can lead to the aliasing of small scale power into what is meant to be a probe of the largest scales. Previously, we developed an optimal ``minimum variance'' (MV) weighting scheme, designed to overcome this problem by minimizing the difference between the measured bulk flow (BF) and that which would be measured by an ideal survey. Here we extend this MV analysis to include the shear and octupole moments, which are designed to have almost no correlations between them so that they are virtually orthogonal. We apply this MV analysis to a compilation of all major peculiar velocity surveys, consisting of 4536 measurements. Our estimate of the BF on scales of ~ 100 Mpc/h has a magnitude of |v|= 416 +/- 78 km/s towards Galactic l = 282 degree +/- 11 degree and b = 6 degree +/- 6 degree. This result is in disagreement with LCDM with WMAP5 cosmological parameters at a high confidence level, but is in good agreement with our previous MV result without an orthogonality constraint, showing that the shear and octupole moments did not contaminate the previous BF measurement. The shear and octupole moments are consistent with WMAP5 power spectrum, although the measurement noise is larger for these moments than for the BF. The relatively low shear moments suggest that the sources responsible for the BF are at large distances.Comment: 13 Pages, 7 figures, 4 tables. Some changes to reflect the published versio

Reduced Lentivirus Susceptibility in Sheep with TMEM154 Mutations

Visna/Maedi, or ovine progressive pneumonia (OPP) as it is known in the United States, is an incurable slow-acting disease of sheep caused by persistent lentivirus infection. This disease affects multiple tissues, including those of the respiratory and central nervous systems. Our aim was to identify ovine genetic risk factors for lentivirus infection. Sixty-nine matched pairs of infected cases and uninfected controls were identified among 736 naturally exposed sheep older than five years of age. These pairs were used in a genome-wide association study with 50,614 markers. A single SNP was identified in the ovine transmembrane protein (TMEM154) that exceeded genome-wide significance (unadjusted p-value 3×10−9). Sanger sequencing of the ovine TMEM154 coding region identified six missense and two frameshift deletion mutations in the predicted signal peptide and extracellular domain. Two TMEM154 haplotypes encoding glutamate (E) at position 35 were associated with infection while a third haplotype with lysine (K) at position 35 was not. Haplotypes encoding full-length E35 isoforms were analyzed together as genetic risk factors in a multi-breed, matched case-control design, with 61 pairs of 4-year-old ewes. The odds of infection for ewes with one copy of a full-length TMEM154 E35 allele were 28 times greater than the odds for those without (p-value<0.0001, 95% CI 5–1,100). In a combined analysis of nine cohorts with 2,705 sheep from Nebraska, Idaho, and Iowa, the relative risk of infection was 2.85 times greater for sheep with a full-length TMEM154 E35 allele (p-value<0.0001, 95% CI 2.36–3.43). Although rare, some sheep were homozygous for TMEM154 deletion mutations and remained uninfected despite a lifetime of significant exposure. Together, these findings indicate that TMEM154 may play a central role in ovine lentivirus infection and removing sheep with the most susceptible genotypes may help eradicate OPP and protect flocks from reinfection

The Marine Microbial Eukaryote Transcriptome Sequencing Project (MMETSP): illuminating the functional diversity of eukaryotic life in the oceans through transcriptome sequencing

International audienceCurrent sampling of genomic sequence data from eukaryotes is relatively poor, biased, and inadequate to address important questions about their biology, evolution, and ecology; this Community Page describes a resource of 700 transcriptomes from marine microbial eukaryotes to help understand their role in the world's oceans

The Marine Microbial Eukaryote Transcriptome Sequencing Project (MMETSP): illuminating the functional diversity of eukaryotic life in the oceans through transcriptome sequencing.

Microbial ecology is plagued by problems of an abstract nature. Cell sizes are so small and population sizes so large that both are virtually incomprehensible. Niches are so far from our everyday experience as to make their very definition elusive. Organisms that may be abundant and critical to our survival are little understood, seldom described and/or cultured, and sometimes yet to be even seen. One way to confront these problems is to use data of an even more abstract nature: molecular sequence data. Massive environmental nucleic acid sequencing, such as metagenomics or metatranscriptomics, promises functional analysis of microbial communities as a whole, without prior knowledge of which organisms are in the environment or exactly how they are interacting. But sequence-based ecological studies nearly always use a comparative approach, and that requires relevant reference sequences, which are an extremely limited resource when it comes to microbial eukaryotes. In practice, this means sequence databases need to be populated with enormous quantities of data for which we have some certainties about the source. Most important is the taxonomic identity of the organism from which a sequence is derived and as much functional identification of the encoded proteins as possible. In an ideal world, such information would be available as a large set of complete, well curated, and annotated genomes for all the major organisms from the environment in question. Reality substantially diverges from this ideal, but at least for bacterial molecular ecology, there is a database consisting of thousands of complete genomes from a wide range of taxa, supplemented by a phylogeny-driven approach to diversifying genomics [2]. For eukaryotes, the number of available genomes is far, far fewer, and we have relied much more heavily on random growth of sequence databases, raising the question as to whether this is fit for purpose