2 research outputs found
Heterocyclic synthesis with nitriles: synthesis of pyrazolopyrimidine and pyrazolopyridine derivatives
The reaction of N1-substituted-5-amino-4-cyanopyrazoles with malononitrile and diethylmalonate occurs with formation of 6-substituted pyrazolo[3,4-d]pyrimidines, and pyrazolo[3,4-b]pyridines respectively. The structures of the products and conceivable mechanisms are discussed.Fundação para a Ciência e Tecnologia - SFRH/BPD/31490/2006Fundo Europeu de Desenvolvimento Regional (FEDER) - POCTI-SFA-3-68