Crohn’s Disease Treated by Chinese Medicine

Crohn’s disease is an inflammatory bowel disease with variable clinical symptoms, it can affect the whole gastrointestinal tract from the oral cavity to the anus and lead to lower quality of life and greater social and economicloss. Traditional Chinese medicine (TCM) has a long history and is unique characteristic by the theory of overall concept and treatment based on syndrome differentiation, it should be an important part of world medicine. This chapter introduces the research advance of Crohn’s disease in TCM, including its name, location, etiology and pathogenesis, syndrome differentiation, therapeutic criteria, treatment methods and other contents. The mechanism of TCM treatment of Crohn’s disease remains to be further studied

FFSSE: Flexible Forward Secure Searchable Encryption with Efficient Performance

Searchable Symmetric Encryption (SSE) has been widely applied in the design of encrypted database for exact queries or even range queries in practice. In spite of its efficiency and functionalities, it always suffers from information leakages. Some recent attacks point out that forward privacy is the desirable security goal. However, there are only a very small number of schemes achieving this security. In this paper, we propose a new forward secure SSE scheme, denoted as ``FFSSE\u27\u27, which has the best performance in the literature, namely with fast search operation, fast token generation and O(1) update complexity. It also supports both add and delete operations in the unique instance. Technically, we exploit a novel ``key-based blocks chain\u27\u27 technique based on symmetric cryptographic primitive, which can be deployed in arbitrary index tree structures or key-value structures directly to provide forward privacy. In order to reduce the storage on the client side, we further propose an efficient permutation technique (with similar function as trapdoor permutation) to support the re-construction of the search tokens. Experiments show that our scheme is 4 times, 300 times and 300 times faster than the state-of-the-art forward private SSE scheme (proposed in CCS 2016) in search, update and token generation, respectively. Security analysis shows that our scheme is secure

Characterization of phenolics and antioxidant abilities of red navel orange “Cara Cara” harvested from five regions of China

Red-flesh navel orange “Cara Cara” is attractive for customers with its bright red color and has been widely planted in China. In this study, phenolic compounds in “Cara Cara” harvested from five different regions were identified and quantified by ultra high performance liquid chromatography (UPLC) coupled with Quadrupole-Time of Flight -Electrospray ionization-mass spectrometry (Q-TOF-ESI-MSn). Their antioxidant abilities were evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) and oxygen radical absorption capacity (ORAC) assays. Twenty phenolics were detected in crude extraction, with hesperidin (29.36–44.06%) as the dominant component, followed by narirutin (13.44–17.03%) and apigenin-6,8-di-C-glucoside (8.28–12.38%). No free phenolic acid was found in crude extracts and three free phenolic acids (FPA) were determined through alkaline hydrolysis, wherein ferulic acid (86.22–90.49%) existed dominantly. Fujian “Cara Cara” showed the highest total phenolic index (TPI) and total flavonoid index (TFI) values, while the lowest TPI and TFI values were detect in Chongqing “Cara Cara”. DPPH value showed positive correlation with TPC value (r2 = 0.921), while no correlation was found between ORAC and phenolic contents

Revisiting frequency-smoothing encryption: new security definitions and efficient construction

Abstract Deterministic encryption (DET) allows for fast retrieval of encrypted information, but it would cause significant leakage of frequency information of the underlying data, which results in an array of inference attacks. Simply replacing DET with fully randomized encryption is often undesirable in the scenario of an encrypted database since it incurs a large overhead in query and storage. Frequency Smoothing Encryption (FSE) is a practical encryption scheme to protect frequency information. Current FSE constructions still fall short of efficiency and a reasonable security definition. We revisit FSE and propose two security definitions from both theoretical and practical perspectives. Furthermore, we adopt a novel partitioning strategy to construct a new FSE scheme to improve performance. Experimental results show that compared with others, our scheme achieves excellent query performance while attaining security against inference attacks

A Lifetime Optimization Algorithm Limited by Data Transmission Delay and Hops for Mobile Sink-Based Wireless Sensor Networks

To improve the lifetime of mobile sink-based wireless sensor networks and considering that data transmission delay and hops are limited in actual system, a lifetime optimization algorithm limited by data transmission delay and hops (LOA_DH) for mobile sink-based wireless sensor networks is proposed. In LOA_DH, some constraints are analyzed, and an optimization model is proposed. Maximum capacity path routing algorithm is used to calculate the energy consumption of communication. Improved genetic algorithm which modifies individuals to meet all constraints is used to solve the optimization model. The optimal solution of sink node’s sojourn grid centers and sojourn times which maximizes network lifetime is obtained. Simulation results show that, in three node distribution scenes, LOA_DH can find the movement solution of sink node which covers all sensor nodes. Compared with MCP_RAND, MCP_GMRE, and EASR, the solution improves network lifetime and reduces average amount of node discarded data and average energy consumption of nodes

Long noncoding RNAs: glycolysis regulators in gynaecologic cancers

Abstract The three most common gynaecologic cancers that seriously threaten female lives and health are ovarian cancer, cervical cancer, and endometrial cancer. Glycolysis plays a vital role in gynaecologic cancers. Several long noncoding RNAs (lncRNAs) are known to function as oncogenic molecules. LncRNAs impact downstream target genes by acting as ceRNAs, guides, scaffolds, decoys, or signalling molecules. However, the role of glycolysis-related lncRNAs in regulating gynaecologic cancers remains poorly understood. In this review, we emphasize the functional roles of many lncRNAs that have been found to promote glycolysis in gynaecologic cancers and discuss reasonable strategies for future research