1,409 research outputs found
Fast field-cycling NMR of cartilage : a way toward molecular imaging
Peer reviewedPublisher PD
Space power distribution system technology. Volume 2: Autonomous power management
Electrical power subsystem requirements, power management system functional requirements, algorithms, power management subsystem, hardware development, and trade studies and analyses are discussed
Space power distribution system technology. Volume 1: Reference EPS design
The multihundred kilowatt electrical power aspects of a mannable space platform in low Earth orbit is analyzed from a cost and technology viewpoint. At the projected orbital altitudes, Shuttle launch and servicing are technically and economically viable. Power generation is specified as photovoltaic consistent with projected planning. The cost models and trades are based upon a zero interest rate (the government taxes concurrently as required), constant dollars (1980), and costs derived in the first half of 1980. Space platform utilization of up to 30 years is evaluated to fully understand the impact of resupply and replacement as satellite missions are extended. Such lifetimes are potentially realizable with Shuttle servicing capability and are economically desirable
Dirac-Schr\"odinger equation for quark-antiquark bound states and derivation of its interaction kerne
The four-dimensional Dirac-Schr\"odinger equation satisfied by
quark-antiquark bound states is derived from Quantum Chromodynamics. Different
from the Bethe-Salpeter equation, the equation derived is a kind of first-order
differential equations of Schr\"odinger-type in the position space. Especially,
the interaction kernel in the equation is given by two different closed
expressions. One expression which contains only a few types of Green's
functions is derived with the aid of the equations of motion satisfied by some
kinds of Green's functions. Another expression which is represented in terms of
the quark, antiquark and gluon propagators and some kinds of proper vertices is
derived by means of the technique of irreducible decomposition of Green's
functions. The kernel derived not only can easily be calculated by the
perturbation method, but also provides a suitable basis for nonperturbative
investigations. Furthermore, it is shown that the four-dimensinal
Dirac-Schr\"odinger equation and its kernel can directly be reduced to rigorous
three-dimensional forms in the equal-time Lorentz frame and the
Dirac-Schr\"odinger equation can be reduced to an equivalent
Pauli-Schr\"odinger equation which is represented in the Pauli spinor space. To
show the applicability of the closed expressions derived and to demonstrate the
equivalence between the two different expressions of the kernel, the t-channel
and s-channel one gluon exchange kernels are chosen as an example to show how
they are derived from the closed expressions. In addition, the connection of
the Dirac-Schr\"odinger equation with the Bethe-Salpeter equation is discussed
The homotopy theory of simplicial props
The category of (colored) props is an enhancement of the category of colored
operads, and thus of the category of small categories. In this paper, the
second in a series on "higher props," we show that the category of all small
colored simplicial props admits a cofibrantly generated model category
structure. With this model structure, the forgetful functor from props to
operads is a right Quillen functor.Comment: Final version, to appear in Israel J. Mat
Homotopy Theoretic Models of Type Theory
We introduce the notion of a logical model category which is a Quillen model
category satisfying some additional conditions. Those conditions provide enough
expressive power that one can soundly interpret dependent products and sums in
it. On the other hand, those conditions are easy to check and provide a wide
class of models some of which are listed in the paper.Comment: Corrected version of the published articl
Advancing functional connectivity research from association to causation
Cognition and behavior emerge from brain network interactions, such that investigating causal interactions should be central to the study of brain function. Approaches that characterize statistical associations among neural time series-functional connectivity (FC) methods-are likely a good starting point for estimating brain network interactions. Yet only a subset of FC methods ('effective connectivity') is explicitly designed to infer causal interactions from statistical associations. Here we incorporate best practices from diverse areas of FC research to illustrate how FC methods can be refined to improve inferences about neural mechanisms, with properties of causal neural interactions as a common ontology to facilitate cumulative progress across FC approaches. We further demonstrate how the most common FC measures (correlation and coherence) reduce the set of likely causal models, facilitating causal inferences despite major limitations. Alternative FC measures are suggested to immediately start improving causal inferences beyond these common FC measures
Development and Validation of Spectrophotometric, Atomic Absorption and Kinetic Methods for Determination of Moxifloxacin Hydrochloride
Three simple spectrophotometric and atomic absorption spectrometric methods are developed and validated for the determination of moxifloxacin HCl in pure form and in pharmaceutical formulations. Method (A) is a kinetic method based on the oxidation of moxifloxacin HCl by Fe3+ ion in the presence of 1,10 o-phenanthroline (o-phen). Method (B) describes spectrophotometric procedures for determination of moxifloxacin HCl based on its ability to reduce Fe (III) to Fe (II), which was rapidly converted to the corresponding stable coloured complex after reacting with 2,2âČ bipyridyl (bipy). The formation of the tris-complex formed in both methods (A) and (B) were carefully studied and their absorbance were measured at 510 and 520 nm respectively. Method (C) is based on the formation of ion- pair associated between the drug and bismuth (III) tetraiodide in acidic medium to form orangeâred ion-pair associates. This associate can be quantitatively determined by three different procedures. The formed precipitate is either filtered off, dissolved in acetone and quantified spectrophotometrically at 462 nm (Procedure 1), or decomposed by hydrochloric acid, and the bismuth content is determined by direct atomic absorption spectrometric (Procedure 2). Also the residual unreacted metal complex in the filtrate is determined through its metal content using indirect atomic absorption spectrometric technique (procedure 3). All the proposed methods were validated according to the International Conference on Harmonization (ICH) guidelines, the three proposed methods permit the determination of moxifloxacin HCl in the range of (0.8â6, 0.8â4) for methods A and B, (16â96, 16â96 and 16â72) for procedures 1â3 in method C. The limits of detection and quantitation were calculated, the precision of the methods were satisfactory; the values of relative standard deviations did not exceed 2%. The proposed methods were successfully applied to determine the drug in its pharmaceutical formulations without interference from the common excipients. The results obtained by the proposed methods were comparable with those obtained by the reference method
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