On validation of multibody musculoskeletal models

We review the opportunities to validate multibody musculoskeletal models in view of the current transition of musculoskeletal modelling from a research topic to a practical simulation tool in product design, healthcare and other important applications. This transition creates a new need for justification that the models are adequate representations of the systems they simulate. The need for a consistent terminology and established standards is identified and knowledge from fields with a more progressed state-of-the-art in verification and validation is introduced. A number of practical steps for improvement of the validation of multibody musculoskeletal models are pointed out and directions for future research in the field are proposed. It is hoped that a more structured approach to model validation can help to improve the credibility of musculoskeletal models. </jats:p

Muscle-tendon unit parameter estimation of a Hill-type musculoskeletal model based on experimentally obtained subject-specific torque profiles.

The aim of this study was to generate a subject-specific musculoskeletal muscle model, based on isometric and isovelocity measurements of the whole lower extremity. A two-step optimisation procedure is presented for optimising the muscle-tendon parameters for isometric and isovelocity joint torque profiles. A significant improvement in the prediction of joint torque profiles for both the solely isometric and a combined isometric and dynamic method of optimization when compared to the standard scaling method of The AnyBody Modeling System was observed. Depending on the specific purpose of the model, it may be worth considering whether the isometric-only would be sufficient, or the additional dynamic data are required for the combined approach.N/

AnyPyTools

Fixed: Fix an issue with the pytest plugin when running tests with --load-only option and the "RunDurationCPU" output. Fix a deprecation warning from Pandas when exporting to dataframes.If you use this software, please cite it as below