Qigong exercise could reduce upper limb lymphedema and improve blood flow in breast cancer survivors

Poster Presentation: PO-1261This journal suppl. entitled: Abstracts: 7th World Congress of the International Society of Physical and Rehabilitation Medicine ...OBJECTIVE: To investigate the effects of Qigong exercise on upper limb lymphedema, arterial resistance and blood flow velocity in postmastectomy breast cancer survivors. METHOD: Eleven breast cancer survivors with Qigong experience (mean age: 58.3±10.1 years) were assigned to the experimental group and 12 breast cancer survivors without Qigong experience (mean age: 53.8±4.2 years) were assigned to the control group. After baseline measurements were taken, the experimental group performed 18 Forms Tai Chi Qigong exercise for approximately 6 ...published_or_final_versio

Bone mineral density, balance performance, balance self-efficacy and falls in breast cancer survivors with and without Qigong training: An observational study

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Effects of a 6-month Tai Chi Qigong program on arterial hemodynamics and functional aerobic capacity in survivors of nasopharyngeal cancer

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Effects of Qigong training on health-related quality of life, functioning, and cancer-related symptoms in survivors of nasopharyngeal cancer: A pilot study

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Shoulder mobility, muscular strength and quality of life in breast cancer survivors with and without Tai Chi Qigong training

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Effects of qigong exercise on upper limb lymphedema and blood flow in survivors of breast cancer: A pilot study

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The effects of a 6-month Tai Chi Qigong training program on temporomandibular, cervical and shoulder joint mobility and sleep problems in nasopharyngeal cancer survivors

Introduction. Nasopharyngeal cancer (NPC) survivors often sustain head–neck–shoulder impairments from conventional treatments, which could disturb sleep. This novel study aimed to examine the efficacy of Tai Chi (TC) Qigong in optimizing temporomandibular joint (TMJ), cervical, and shoulder joint mobility and reducing sleep problems in NPC survivors. Methods. Fifty-two NPC survivors participated in the study. The experimental group (n = 25) received 6 months of TC Qigong training (1.5 h/session; 4 sessions/wk including self-practice) while the control group (n = 27) received no training. Cervical side flexion and rotation, shoulder flexion and horizontal flexion range of motion (ROM), mouth opening capacity (interincisor distance), and sleep problems (Medical Outcomes Study Sleep Scale) were assessed at baseline, mid-intervention (3 months), immediately after TC Qigong training, and at 6-month follow-up. Results. Intention-to-treat analysis revealed improvement in cervical side flexion ROM only (P .008) after the TC Qigong training. Deterioration was observed in shoulder flexion ROM and mouth opening capacity in the no-training controls over time (P < .008). Sleep problems also decreased in the TC Qigong group (P < .008), and this effect was most profound during the follow-up period. In addition, improvement in cervical side flexion ROM was associated with a reduction in sleep problems in the experimental group after TC Qigong training (P < .05). Conclusions. The 6-month TC Qigong intervention improved neck mobility, maintained TMJ and shoulder joint mobility, and reduced sleep problems for NPC survivors. TC Qigong could be an effective nonpharmacological intervention for managing progressive trismus, chronic neck and shoulder hypomobility, and reducing sleep problems among NPC survivors.postprin

Haemophagocytic lymphohistiocytosis: An uncommon clinical presentation of tuberculosis

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Shoulder mobility, muscular strength, and quality of life in breast cancer survivors with and without tai chi qigong training

Author name used in this publication: Shamay S. M. NgAuthor name used in this publication: Joanne W. Y. Chung2012-2013 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Excess α-synuclein compromises phagocytosis in iPSC-derived macrophages

To examine the pathogenic role of α-synuclein (αS) in Parkinson's Disease, we have generated induced Pluripotent Stem Cell lines from early onset Parkinson's Disease patients with SNCA A53T and SNCA Triplication mutations, and in this study have differentiated them to PSC-macrophages (pMac), which recapitulate many features of their brain-resident cousins, microglia. We show that SNCA Triplication pMac, but not A53T pMac, have significantly increased intracellular αS versus controls and release significantly more αS to the medium. SNCA Triplication pMac, but not A53T pMac, show significantly reduced phagocytosis capability and this can be phenocopied by adding monomeric αS to the cell culture medium of control pMac. Fibrillar αS is taken up by pMac by actin-rearrangement-dependent pathways, and monomeric αS by actin-independent pathways. Finally, pMac degrade αS and this can be arrested by blocking lysosomal and proteasomal pathways. Together, these results show that macrophages are capable of clearing αS, but that high levels of exogenous or endogenous αS compromise this ability, likely a vicious cycle scenario faced by microglia in Parkinson's disease