La aristocracia ibérica ante la romanización. Ideología y espacios funerarios en Marroquíes Bajos (Jaén)

We present the study of the necropolis of a suburban settlement of the Roman city of Aurgi (Jaén). Through the formal and ideological study of these burial grounds, we present a particular situation of endurance of Iberian traditions in the context of Romanization in the Upper Guadalquivir.Presentamos el estudio de las necrópolis de un asentamiento periurbano de la ciudad romana de Aurgi (Jaén), en el que, a través del estudio formal e ideológico de los espacios funerarios, planteamos una situación concreta de perduración de las tradiciones ibéricas en el contexto de la romanización en el Alto Guadalquivir

Non-parametric discretization for probabilistic labeled data

Probabilistic label learning is a challenging task that arises from recent real-world problems within the weakly supervised classification framework. In this task algorithms have to deal with datasets where each instance has associated a set of probabilities belonging to different class labels. In this paper, we propose a supervised univariate non-parametric discretization algorithm based on kernel density estimation that can deal with probabilistic labeled data. The algorithm takes advantage of the estimation of the class conditional densities to produce different sets of cut points according to different smoothing parameters of the kernel. Then, the best set of cut points is selected according to a given supervised classification performance measure. The computational complexity is O(N log N ), where N is the number of instances. The proposal is tested on simulated probabilistic labeled data, which allows assessing the behavior with different noise degrees. The results show that the algorithm outperforms other discretization algorithms and is robust to different degrees of uncertainty.Aritz Pérez is supported by the Basque Government through the BERC 2022–2025 and the Elkartek programs, and by the Ministry of Science, Innovation and Universities: BCAM Severo Ochoa accreditation SEV-2017-0718. Borja Calvo is supported by the Spanish Ministry of Science and Innovation (Grant PID2019-104966GB-I00) and by the Basque Goverment’s ELKARTEK program (grant KK-2020/00049

Optimisation of a vertical axis tidal turbine and testing of a prototype in an unblocked environment

Vertical Axis Tidal Turbines (VATTs) have become the subject of increased interest in recent decades, but the development of this type of hydrokinetic turbine has faced several challenges that have not yet been overcome. The influence of rotor parameters on turbine performance is one of these challenges. No axiom can be found in the literature about the effect of these parameters on the turbine behaviour, and sometimes research projects even show contradictory results. As a consequence, parameters that define turbine rotors may differ substantially from each other but have performed similarly in terms of efficiency. In relation to this matter, experimental modelling has been carried out in the School of Engineering facility at Cardiff University. Using small-scale set-ups, experimental testing provided useful and reliable information that shed light into these design uncertainties. Blade roughness has been found to have a great impact on the turbine behaviour, and the influence of this parameter has been tested and analysed in depth in a subsequent chapter of the thesis. Apart from the parametric analysis, a mechanical and an electrical system were utilised for the turbine set up. Thanks to these different systems of energy conversion, it was possible to compare the extracted power and to evaluate their inherent losses. Electricity was generated from the electrical approach, which was very useful in order to accurately evaluate the turbine efficiency. Taking into account the results coming from physical testing, an optimised prototype of a VATT was designed and manufactured; estimated to be a 1:15 scale device. Not just the rotor but the whole super structure was built, in order to analyse both the efficiency and the performance of the rotor, as well as the 1 structural response of the entire device. Performing experimental testing without removing the effect that a blocked channel provides to the turbine rotation is no trivial issue, and intermediate scale tests will become a fundamental step for recognition of the technology. Aiming to achieve a reliable source of information, the manufactured tidal turbine prototype has been tested in a water sports centre (White Water Rafting Centre, Cardiff). There is a clear lack of information in the literature about testing tidal turbines on an intermediate scale, and the chance to test a tidal turbine is a very valuable opportunity. The experiments were accomplished in a very similar environment to a real tidal stream, but with the related advantages of complete control over the turbine deployment. Thus, these experiments are considered to provide very useful data for scientific knowledge and also the tidal stream energy sector. Finally, the study of the hydrodynamic turbine wake in small scale was carried out. Not only velocity measurements were collected at the turbine operating point, but also water elevations upstream and downstream were measured by using depth gauges based on water conductivity. At the time of writing and to the best of the authors’ knowledge, not many research articles have studied the wake characteristics of vertical axis tidal stream turbines, and none have used this equipment. The quality of the data is deemed to be excellent and the following process of the information described perfectly the near and far wake. This could be extremely useful for a future scale-up of the turbine, and the development of an array.

A CULTURA NEGRA ATRAVÉS DA EDUCAÇÃO PATRIMONIAL: MAQUETES COMO FERRAMENTA PARA O ENSINO DE VALORES HUMANOS.

O trabalho aqui apresentado dá ênfase a um resgate cultural da história negra, e sua conseqüente valorização perante a sociedade atual, tendo como principal alvo as escolas. Visto que há um esquecimento por muitos de que o negro é um dos grandes patamares da história brasileira, o artigo tenta unir a idéia de que este não foi apenas um pequeno detalhe da história brasileira, e sim um importante percussor da formação da identidade nacional. A partir deste contexto, a educação patrimonial entra com o viés de tentar fazer um resgate cultural e valorização da história negra, através da construção da maquete de um navio negreiro, onde é salientada a questão da escravidão, citando o tráfico de escravos, com seu caráter de fornecimento de mão de obra para o novo mundo que então surgi

Analysis of potential risks from the bacterial communities associated with air-contact surfaces from tilapia (Oreochromis niloticus) fish farming

Tilapia farming is a promising growing sector in aquaculture. Yet, there are limited studies on microbiological risks associated to tilapia farms. The aim of the present study was to analyse the bacterial communities from solid surfaces in contact with air in a tilapia farm in order to evaluate the presence of bacteria potentially toxinogenic or pathogenic to humans or animals. Samples from a local tilapia farm (tank wall, aerator, water outlets, sink and floor) were analyzed by high throughput sequencing technology. Sequences were assigned to operational taxonomic units (OTUs). Proteobacteria was the main phylum represented in most samples (except for one). Cyanobacteria were a relevant phylum in the inner wall from the fattening tank and the wet floor by the pre-fattening tank. Bacteroidetes were the second phylum in relative abundance for samples from the larval rearing tank and the pre-fattening tank and one sample from the fattening tank. Fusobacteria showed highest relative abundances in samples from the larval rearing tank and pre-fattening tank. Other phyla (Verrucomicrobia, Actinobacteria, Firmicutes, Planktomycetes, Acidobacteria, Chloroflexi, Chlorobi, Gemmatiomonadetes or Fibrobacters) had lower relative abundances. A large fraction of the reads (ranging from 43.67% to 72.25%) were assigned to uncultured bacteria. Genus Acinetobacter (mainly A. calcoaceticus/baumanni) was the predominant OTU in the aerator of the fattening tank and also in the nearby sink on the floor. The genera Cetobacterium and Bacteroides showed highest relative abundances in the samples from the larval rearing tank and the pre-fattening tank. Genera including fish pathogens (Fusobacterium, Aeromonas) were only detected at low relative abundances. Potential human pathogens other than Acinetobacter were either not detected or had very low relative abundances (< 0.01%). The results of the study suggest that the main risk factors to be monitored in tilapia farm are putative human pathogenic Acinetobacter and potential cyanotoxin-producing cyanobacteria.This work was supported by the University of Jaén (Research Structure AGR230). We also acknowledge the Campus de Excelencia Internacional Agroalimentario CeiA3.Conflict of interes

Estado de desarrollo de la Telemedicina a nivel internacional, nacional y de la Región del Maule

94 p.Este trabajo de tesis tiene como objetivo general presentar la realidad actual de la Telemedicina y la evolución que ha tenido a nivel internacional, nacional y regional investigando los principales aspectos que afectan su desarrollo, considerando además los actores que interactúan en ella, así como las áreas involucradas en la misma como lo son la salud privada, pública y la academia. Para lograr dicho objetivo general se plantean tres objetivos específicos; los cuales son: (i) Efectuar una revisión bibliográfica sobre la Telemedicina, presentando la evidencia internacional de Estados Unidos, Reino Unido,Sudáfrica, Japón, Australia y Chile. (ii) Analizar las principales brechas que afectan el desarrollo de la Telemedicina considerando los legales, sustentabilidad y estándares de infraestructura de comunicación. (iii) Desarrollar una caracterización de los actores relevantes a nivel nacional considerandopara ello el sector privado, sector público y el papel de la academia (Universidades). Para dar cumplimiento a los dos primeros objetivos se realizó una búsqueda, selección y organización de las fuentes de información, en lo que respecta al tercer objetivo se trabajó analizando las empresas del rubro salud de acuerdo al volumen de ventas en impuestos internos (SII), para luego estudiar las empresas proveedoras de tecnologías agrupadas en ACTI, Chiletec, ACHISA. El paso siguiente fue estimar la demanda de servicios públicos de mediante los montos de licitaciones de Mercado Público para proponer mejoras./ABSTRAC: The general objective of this thesis work is to study the current reality of Telemedicine and the evolution it has undergone at international, national and regional level, investigating the main aspects that have an impact on its development, considering also the actors that interact in it, as well as the areas involved in it such as private and public health and academia. To achieve this general objective, three specific objectives are set out: (i) To carry out a bibliographic review on Telemedicine, presenting the international evidence of the United States, United Kingdom, South Africa, Japan, Australia and Chile. (ii) To analyze the main aspects that affect the development of Telemedicine considering the laws, sustainability and standards of communication infrastructure. (iii) Develop a characterization of the relevant actors at a national level considering the private sector, the public sector and the role of academia (Universities). In order to fulfil the first two objectives, a research, a selection and an organization of the sources of information were carried out. Regarding the third objective, work was done to analyze the companies of the health sector according to the Internal Revenue Service (SII), and then to study the companies supplying technologies grouped in ACTI, Chiletec, ACHISA. The next step was to estimate the demand for public services through the amounts of public market bids to propose improvements

Recalling Rowe: Le Corbusier y la aritmética de la villa ideal

Las matemáticas de la vivienda ideal, ensayo escrito por el historiador y crítico de arquitectura inglés Colin Rowe y publicado en 1947, ha pasado a la historia de la teoría de la arquitectura como un texto clave para analizar las raíces clásicas de la arquitectura moderna. En él, se establecen puntos en común entre la arquitectura del Andrea Palladio y Le Corbusier, concretamente se estudia el vínculo aparentemente inexistente entre diferentes villas renacentistas y modernas siguiendo el método formalista y de análisis geométrico usado por su maestro Rudolf Wittkover en Los fundamentos de la arquitectura en la edad del humanismo (1942). Colin Rowe analiza villas de uno y otro arquitecto reduciendo sus plantas a una geometría compositiva básica, la compara y establece relaciones entre unas y otras, concluyendo que hay semejanzas entre ellas. Sin embargo, las obra de Le Corbusier elegidas por Rowe para defender su teoría se limita a dos: Villa Stein, y la Villa Savoye. ¿Podríamos extrapolar las conclusiones de Rowe al resto de las villas de Le Corbusier y demostrar que todas sus villas se basan en un sistema compositivo palladiano? Este trabajo de fin de grado toma como base este artículo de Rowe y busca constatar si realmente la tesis de Rowe se cumple el otras villas de Le Corbusier no estudiadas por Rowe y, de ser así, descubrir si estas semejanzas pueden encontrarse no solo en las plantas de sus proyectos sino también en el espacio arquitectónico proyecto por ambos arquitectos

Anti-MPER antibodies with heterogeneous neutralization capacity are detectable in most untreated HIV-1 infected individuals

Background The MPER region of the HIV-1 envelope glycoprotein gp41 is targeted by broadly neutralizing antibodies. However, the localization of this epitope in a hydrophobic environment seems to hamper the elicitation of these antibodies in HIV infected individuals. We have quantified and characterized anti-MPER antibodies by ELISA and by flow cytometry using a collection of mini gp41-derived proteins expressed on the surface of 293T cells. Longitudinal plasma samples from 35 HIV-1 infected individuals were assayed for MPER recognition and MPER-dependent neutralizing capacity using HIV-2 viruses engrafted with HIV-1 MPER sequences. Results Miniproteins devoid of the cysteine loop of gp41 exposed the MPER on 293T cell membrane. Anti-MPER antibodies were identified in most individuals and were stable when analyzed in longitudinal samples. The magnitude of the responses was strongly correlated with the global response to the HIV-1 envelope glycoprotein, suggesting no specific limitation for anti-MPER antibodies. Peptide mapping showed poor recognition of the C-terminal MPER moiety and a wide presence of antibodies against the 2F5 epitope. However, antibody titers failed to correlate with 2F5-blocking activity and, more importantly, with the specific neutralization of HIV-2 chimeric viruses bearing the HIV-1 MPER sequence; suggesting a strong functional heterogeneity in anti-MPER humoral responses. Conclusions Anti-MPER antibodies can be detected in the vast majority of HIV-1 infected individuals and are generated in the context of the global anti-Env response. However, the neutralizing capacity is heterogeneous suggesting that eliciting neutralizing anti-MPER antibodies by immunization might require refinement of immunogens to skip nonneutralizing responses