Lubrication in cold rolling: Elasto-plasto-hydrodynamic lubrication

A model has been developed with respect to hydrodynamic lubrication in cold rolling. The basic model describes the configuration of a rigid, perfectly plastic sheet rolled by a rigid work roll. The governing equations have been solved throughout the complete contact area, i.e. the inlet, the work zone and the outlet zone. Multi-level techniques have been applied to solve these equations together with boundary conditions, resulting in an algorithm solving the problem in O(n) operations. This means that the distribution of the pressure and the traction force in the lubricant film, and the shape of this film, as well as the plastic deformation of the sheet, can be accurately calculated for a large number of nodal points on a minicomputer. Subsequently elastic deformation, work hardening and dynamic behaviour of the flow stress have been incorporated in the model. It will be shown that the influence of these effects on the film thickness or the pressure distribution is considerable

Effective Viscosity Determination for Lubrication Systems Using the Lincoln Ventmeter

The selection criteria for lubricating grease in rolling bearings are different from those for a lubrication system that provides the bearings with grease. For optimum performance in bearings, the main properties are related to lubrication, whereas for optimum performance in a lubrication system, the grease should fulfill flow criteria. The main flow properties of a grease are its viscosity at low shear rates (including shear thinning) and its yield stress. In this article, a simple and robust method is described to measure both parameters simultaneously. The method is based on measuring flow through a pipe, simulating the so-called venting process, which makes the method directly applicable to lubrication systems. The Ventmeter measurements are compared to those obtained with plate–plate and capillary flow rheometers. It will be shown that the measured effective viscosity can readily be used to predict the pressure drop in lubrication systems, which makes it possible to design the system for optimum performanc

Film Thickness Modulations in Starved Elastohydrodynamically Lubricated Contacts Induced by Timne-Varying Lubricant Supply

Many elastohydrodynamically lubricated contacts in practical applications, e.g., in bearings, operate in the starved lubrication regime. As a result their performance is sensitive to variations of the lubricant layers present on the surfaces, which form the supply to the contact. Their shape is often determined by previous overrollings of the track and also by replenishment mechanisms and various migration effects. Variations of the layers induced in the direction of rolling lead to a time-varying lubricant supply to the contact. In this paper, by means of numerical simulations using a starved lubrication model, the film thickness modulations in the center of the contact induced by a harmonically varying inlet supply have been investigated. First, for a given load condition and layer wavelength, the effect of the nominal layer thickness (degree of starvation) and the layer variation amplitude is illustrated. Subsequently, using results for different load conditions, wavelengths, and degrees of starvation, it is shown that the response of the contact to such variations is determined by a nondimensional parameter, which represents the ratio of the entrainment length of the contact to the wavelength of the induced variation, and by the degree of starvation. A simple formula is presented for use in engineering predicting the ratio of the amplitude of the film modulations in the center of the contact to the amplitude of the layer variations in the inlet

Effect of First-Pass Reperfusion on Outcome After Endovascular Treatment for Ischemic Stroke

Background First-pass reperfusion (FPR) is associated with favorable outcome after endovascular treatment. It is unknown whether this effect is independent of patient characteristics and whether FPR has better outcomes compared with excellent reperfusion (Expanded Thrombolysis in Cerebral Infarction [eTICI] 2C-3) after multiple-passes reperfusion. We aimed to evaluate the association between FPR and outcome with adjustment for patient, imaging, and treatment characteristics to single out the contribution of FPR. Methods and Results FPR was defined as eTICI 2C-3 after 1 pass. Multivariable regression models were used to investigate characteristics associated with FPR and to investigate the effect of FPR on outcomes. We included 2686 patients of the MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands) Registry. Factors associated with FPR were as follows: history of hyperlipidemia (adjusted odds ratio [OR], 1.05; 95% CI, 1.01-1.10), middle cerebral artery versus intracranial carotid artery occlusion (adjusted OR, 1.11; 95% CI, 1.06-1.16), and aspiration versus stent thrombectomy (adjusted OR, 1.07; 95% CI, 1.03-1.11). Interventionist experience increased the likelihood of FPR (adjusted OR, 1.03 per 50 patients previously treated; 95% CI, 1.01-1.06). Adjusted for patient, imaging, and treatment characteristics, FPR remained associated with a better 24-hour National Institutes of Health Stroke Scale (NIHSS) score (-37%; 95% CI, -43% to -31%) and a better modified Rankin Scale (mRS) score at 3 months (adjusted common OR, 2.16; 95% CI, 1.83-2.54) compared with no FPR (multiple-passes reperfusion+no excellent reperfusion), and compared with multiple-passes reperfusion alone (24-hour NIHSS score, (-23%; 95% CI, -31% to -14%), and mRS score (adjusted common OR, 1.45; 95% CI, 1.19-1.78)). Conclusions FPR compared with multiple-passes reperfusion is associated with favorable outcome, independently of patient, imaging, and treatment characteristics. Factors associated with FPR were the experience of the interventionist, history of hyperlipidemia, location of occluded artery, and use of an aspiration device compared with stent thrombectomy

Novel genetic loci associated with hippocampal volume

The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several common neuropsychiatric disorders. To identify the genetic underpinnings of hippocampal structure here we perform a genome-wide association study (GWAS) of 33,536 individuals and discover six independent loci significantly associated with hippocampal volume, four of them novel. Of the novel loci, three lie within genes (ASTN2, DPP4 and MAST4) and one is found 200 kb upstream of SHH. A hippocampal subfield analysis shows that a locus within the MSRB3 gene shows evidence of a localized effect along the dentate gyrus, subiculum, CA1 and fissure. Further, we show that genetic variants associated with decreased hippocampal volume are also associated with increased risk for Alzheimer's disease (rg =-0.155). Our findings suggest novel biological pathways through which human genetic variation influences hippocampal volume and risk for neuropsychiatric illness

Novel genetic loci underlying human intracranial volume identified through genome-wide association

Intracranial volume reflects the maximally attained brain size during development, and remains stable with loss of tissue in late life. It is highly heritable, but the underlying genes remain largely undetermined. In a genome-wide association study of 32,438 adults, we discovered five novel loci for intracranial volume and confirmed two known signals. Four of the loci are also associated with adult human stature, but these remained associated with intracranial volume after adjusting for height. We found a high genetic correlation with child head circumference (ρgenetic=0.748), which indicated a similar genetic background and allowed for the identification of four additional loci through meta-analysis (Ncombined = 37,345). Variants for intracranial volume were also related to childhood and adult cognitive function, Parkinson’s disease, and enriched near genes involved in growth pathways including PI3K–AKT signaling. These findings identify biological underpinnings of intracranial volume and provide genetic support for theories on brain reserve and brain overgrowth

Modern advancements in lubricating grease technology

Grease is one of the major bearing components and the performance of a grease lubricated bearing is strongly determined by the performance of the grease. This paper describes how grease knowledge is linked to improved rolling bearing performance. First the various performance indicators will be described such as rolling bearing life, sealing performance, bearing friction, bearing noise and grease life. Next, the dominating grease parameters and specifications on these aspects will be given. It will also be shown how re-lubrication will enhance the bearing performance. There is synergy between grease formulation and bearing design. In the last years new generation grease lubricated bearings have been developed where grease technology was used to provide significantly lower friction and longer grease life. This was achieved by developing better greases but also by improving the internal bearing design, which could be done by using modern advancements in understanding the lubrication mechanisms. Finally, an outlook will be given on future developments in lubricating greases for rolling bearings. The various test methods are not described in this paper. For an extensive list the reader is referred to [67](Lugt et al., 2013)