9 research outputs found
A CASE OF INCARCERATED DIAPHRAGMATIC HERNIA AFTER PERFORATION OF THE GASTRIC WALL AND DIAPHRAGMA DUE TO ENDOSCOPIC SUBMUCOSAL DISSECTION FOR EARLY GASTRIC CANCER
An efficient algorithm for electromagnetic scattering by a set of perfect conducting cylindrical objects using the artificial neural network
α-Actinin-2 Mediates Spine Morphology and Assembly of the Post-Synaptic Density in Hippocampal Neurons
Management of locally advanced HPV-related oropharyngeal squamous cell carcinoma: where are we?
HPV-related (HPV+) oropharyngeal cancer (OPC) has a better prognosis compared to HPV unrelated (HPV-) OPC. This review summarizes and discusses several of the controversies regarding the management of HPV+ OPC, including the mechanism of its treatment sensitivity, modern surgical techniques, chemotherapy regimens, and treatment de-intensification protocols. We also discuss and reconsider potential adverse prognostic factors such as tumor EGFR expression, tumor hypoxia, and patient smoking history, as well as the significance of retropharyngeal adenopathy. Finally, we discuss elective nodal treatment of uninvolved lymph node stations. While this review does not exhaust all controversies related to the management of HPV+ OPC, it aims to highlight some of the most clinically relevant ones