Agility in virtual environments: the socio-technical approach of distributed agile teams

Purpose – This study aims to understand how distributed agile teams (DATs), encouraged by globalisation, and recently accelerated by the COVID-19 outbreak, adopt agile practices to achieve project goals by working virtually. Design/methodology/approach – This study developed a multiple-case study involving four companies undergoing several changes, especially during the COVID-19 pandemic. The authors collected data mainly through in-depth, face-to-face interviews with seven key informants. Moreover, this study operates data triangulation by referring to secondary data sources and developing a grounded theory data analysis. Findings – The findings highlight three main categories associated with the DAT functioning, namely, “DATs’ implementation issues”, “elements supporting DATs’ implementation” and “outcomes of DATs’ implementation”, that show DATs’ primary triggers, critical aspects and supportive actions for team functioning. Research limitations/implications – This paper produced valuable theoretical knowledge of DATs’ dynamics within a socio-technical approach that distinguishes soft and hard variables supporting DAT implementation. Moreover, the evidence provides useful suggestions for managers about creating an objective-oriented virtual work environment based on DATs’self-organisation, digitally shared leadership and occasional on-site socialisation. Originality/value – This paper provides new and interesting insights that bring to evidence the main variables related to DATs’ adoption and dynamics, showing supporting activities that enhanced their operativity. It provides a valuable descriptive framework for academics and practitioners to understand DATs’ functioning better and take action to improve their implementation

Diversity Loss in Coralligenous Structuring Species Impacted by Fishing Gear and Marine Litter

Coralligenous structuring species (CSS) form a group of marine megabenthic species with an engineering capacity. Since they are highly vulnerable to anthropogenic activities, they have been selected for the Marine Strategy Framework Directive (MSFD) monitoring programs. The pressure and impact of fishing gear and marine litter on these species were evaluated through the image analysis of 54 remotely operated vehicle (ROV) routes along the Campania coasts (Tyrrhenian Sea, Italy). CSS density was calculated as the number of colonies/100 m2. Anthropogenic pressure was estimated as the frequency of frames showing longline, nets, other gear, plastic objects, metal objects, and other litter; while the impact was expressed as the frequency showing necrosis/epibiosis, broken/upturned and covered/entangled colonies. Cnidaria dominate in the Napoli, Campanella and Capri areas, while Bryozoa dominate in Cilento N and Cilento S areas. Campanella and Capri appeared to be the least heterogeneous despite their higher CSS densities, which was possibly related to the dominance of a few species. These areas were the most affected by showing the highest numbers of fishing gear (longlines) and marine litter (metal objects) recorded, amongst which longlines are the most abundant. In addition, these fishing areas are either close to a large urban center or located along popular touristic routes. In all the areas, colonies with necrosis/epibiosis (CNE) impact are present with low-moderate values, while the category gears covering/entangling (GCE) impact prevails in the Campanella and Capri areas, and this is strictly connected to the high presence of fishing gear

Physiological response of the coralline alga Corallina officinalis L. to both predicted long-term increases in temperature and short-term heatwave events

This work was supported by the European Cooperation in Science and Technology (COST) within the COST Action CA15121, advancing marine conservation in the European and contiguous seas (MarCons).Climate change is leading to an increase of mean sea surface temperatures and extreme heat events. There is an urgent need to better understand the capabilities of marine macroalgae to adapt to these rapid changes. In this study, the responses of photosynthesis, respiration, and calcification to elevated temperature in a global warming scenario were investigated in the coralline alga Corallina officinalis. Algae were cultured for 7 weeks under 4 temperature treatments: (1) control under ambient-summer conditions (C, ∼20 °C), (2) simulating a one-week heatwave of 1 °C (HW, Tcontrol+1 °C), (3) elevated temperature (+3, Tcontrol +3 °C), (4) combination of the two previous treatments (HW+3, T+3+1 °C). After exposure at T+3 (up to a Tmax of ∼23 °C), respiration and photosynthesis increased significantly. After 5 weeks, calcification rates were higher at elevated temperatures (T+3 and THW+3) compared to Tcontrol, but at the end of the experiment (7 weeks) calcification decreased significantly at those temperatures beyond the thermal optimum (six-fold at T+3, and three-fold at THW+3, respectively). The same trend was noted for all the physiological processes, suggesting that a prolonged exposure to high temperatures (7 weeks up to T+3) negatively affect the physiology of C. officinalis, as a possible consequence of thermal stress. A one-week heatwave of +1 °C with respect to Tcontrol (at THW) did not affect respiration, photosynthesis, or calcification rates. Conversely, a heatwave of 1 °C, when combined with the 3 °C increase predicted by the end of the century (at THW+3), induced a reduction of physiological rates. Continued increases in both the intensity and frequency of heatwaves under anthropogenic climate change may lead to reduced growth and survival of primary producers such as C. officinalis.PostprintPeer reviewe

Assessment of Structural and Functional Diversity of Mollusc Assemblages within Vermetid Bioconstructions

Dendropoma lebeche is a prosobranch gastropod belonging to the family Vermetidae, which calcifies its shell on hard substrates in dense aggregates, forming biogenic constructions along the western Mediterranean intertidal habitat. It is an important ecosystem engineer and, due to its ecological value, is protected by international convention. The aim of this study is to investigate the mollusc composition and diversity occurring within Spanish vermetid bioconstructions. During the late summer 2013, three distant sites along the Mediterranean coast of Spain were sampled by scraping off the vermetid shells to study their associated assemblages. A total of 600 molluscs were identified within the classes of Polyplacophora (four species), Gastropoda (35 spp.) and Bivalvia (18 spp.). Multivariate analyses revealed significant differences in composition and trophic diversity of mollusc assemblages among the three sites, highlighting a clear geographical gradient. Overall, both herbivores (grazers and deposit feeders) and omnivores were the quantitatively dominant trophic groups, while carnivores (predators and ectoparasites) were very scarce. Our results point out that mollusc assemblages associated with vermetid bioconstructions are rich and diversified, both in populations structure and trophic diversity, confirming the important role of vermetid gastropods as ecosystem engineers and biodiversity enhancers in shallow coastal waters.This study was funded by the Italian Ministry for Education, Universities and Research (Z8HJ5M_008; P.R.I.N. Program 2010–2011: project “Marine bioconstructions: structure, function and management”), and by a Ph.D. fellowship of the first author L.D. (Doctorate in Marine, Terrestrial and Climate Sciences, University of Naples Parthenope)

A eutherian-specific microRNA controls the translation of Satb2 in a model of cortical differentiation

Cerebral cortical development is controlled by key transcription factors that specify the neuronal identities in the different layers. The mechanisms controlling their expression in distinct cells are only partially known. We investigated the expression and stability of Tbr1, Bcl11b, Fezf2, Satb2, and Cux1 mRNAs in single developing mouse cortical cells. We observe that Satb2 mRNA appears much earlier than its protein and in a set of cells broader than expected, suggesting an initial inhibition of its translation, subsequently released during development. Mechanistically, Satb2 30UTR modulates protein translation of GFP reporters during mouse corticogenesis. We select miR541, a eutherian-specific miRNA, and miR-92a/b as the best candidates responsible for SATB2 inhibition, being strongly expressed in early and reduced in late progenitor cells. Their inactivation triggers robust and premature SATB2 translation in both mouse and human cortical cells. Our findings indicate RNA interference as a major mechanism in timing cortical cell identities

An Eutherian-Specific microRNA Controls the Translation of Satb2 in a Model of Cortical Differentiation

Cerebral cortical development is controlled by key transcription factors that specify the neuronal identities in the different cortical layers. These transcription factors are crucial for the identity of the different neurons, but the mechanisms controlling their expression in distinct cells are only partially known. Here we investigate the expression and stability of the mRNAs of Tbr1, Bcl11b, Fezf2, Satb2 and Cux1 in single developing mouse cortical cells. We focus on Satb2 and find that its mRNA expression occurs much earlier than its protein synthesis and in a set of cells broader than expected, suggesting an initially tight control of its translation, which is subsequently de-repressed at late developmental stages. Mechanistically, Satb2 3\u2019UTR modulates protein translation of GFP reporters during mouse corticogenesis. By in vitro pull-down of Satb2 3\u2019UTR-associated miRNAs, we select putative miRNAs responsible for SATB2 inhibition, focusing on those strongly expressed in early progenitor cells and reduced in late cells. miR-541, an Eutherian-specific miRNA, and miR-92a/b are the best candidates and their inactivation triggers robust and premature SATB2 translation in both mouse and human cortical cells. Our findings indicate that RNA interference plays a major role in the timing of cortical cell identity and may be part of the toolkit involved in specifying supra-granular projection neurons

A New Orbiting Deployable System for Small Satellite Observations for Ecology and Earth Observation

In this paper, we present several study cases focused on marine, oceanographic, and atmospheric environments, which would greatly benefit from the use of a deployable system for small satellite observations. As opposed to the large standard ones, small satellites have become an effective and affordable alternative access to space, owing to their lower costs, innovative design and technology, and higher revisiting times, when launched in a constellation configuration. One of the biggest challenges is created by the small satellite instrumentation working in the visible (VIS), infrared (IR), and microwave (MW) spectral ranges, for which the resolution of the acquired data depends on the physical dimension of the telescope and the antenna collecting the signal. In this respect, a deployable payload, fitting the limited size and mass imposed by the small satellite architecture, once unfolded in space, can reach performances similar to those of larger satellites. In this study, we show how ecology and Earth Observations can benefit from data acquired by small satellites, and how they can be further improved thanks to deployable payloads. We focus on DORA—Deployable Optics for Remote sensing Applications—in the VIS to TIR spectral range, and on a planned application in the MW spectral range, and we carry out a radiometric analysis to verify its performances for Earth Observation studies

A study protocol for the evaluation of occupational mutagenic/carcinogenic risks in subjects exposed to antineoplastic drugs: a multicentric project

<p>Abstract</p> <p>Background</p> <p>Some industrial hygiene studies have assessed occupational exposure to antineoplastic drugs; other epidemiological investigations have detected various toxicological effects in exposure groups labeled with the job title. In no research has the same population been studied both environmentally and epidemiologically. The protocol of the epidemiological study presented here uses an integrated environmental and biological monitoring approach. The aim is to assess in hospital nurses preparing and/or administering therapy to cancer patients the current level of occupational exposure to antineoplastic drugs, DNA and chromosome damage as cancer predictive effects, and the association between the two.</p> <p>Methods/Design</p> <p>About 80 healthy non-smoking female nurses, who job it is to prepare or handle antineoplastic drugs, and a reference group of about 80 healthy non-smoking female nurses not occupationally exposed to chemicals will be examined simultaneously in a cross-sectional study. All the workers will be recruited from five hospitals in northern and central Italy after their informed consent has been obtained.</p> <p>Evaluation of surface contamination and dermal exposure to antineoplastic drugs will be assessed by determining cyclophosphamide on selected surfaces (wipes) and on the exposed nurses' clothes (pads). The concentration of unmetabolized cyclophosphamide as a biomarker of internal dose will be measured in end-shift urine samples from exposed nurses.</p> <p>Biomarkers of effect and susceptibility will be assessed in exposed and unexposed nurses: urinary concentration of 8-hydroxy-2-deoxyguanosine; DNA damage detected using the single-cell microgel electrophoresis (comet) assay in peripheral white blood cells; micronuclei and chromosome aberrations in peripheral blood lymphocytes. Genetic polymorphisms for enzymes involved in metabolic detoxification (i.e. glutathione <it>S</it>-transferases) will also be analysed.</p> <p>Using standardized questionnaires, occupational exposure will be determined in exposed nurses only, whereas potential confounders (medicine consumption, lifestyle habits, diet and other non-occupational exposures) will be assessed in both groups of hospital workers.</p> <p>Statistical analysis will be performed to ascertain the association between occupational exposure to antineoplastic drugs and biomarkers of DNA and chromosome damage, after taking into account the effects of individual genetic susceptibility, and the presence of confounding exposures.</p> <p>Discussion</p> <p>The findings of the study will be useful in updating prevention procedures for handling antineoplastic drugs.</p

A new approach to assess marine opportunity costs and monetary values for spatial planning and conservation; the case study of Gulf of Naples, Mediterranean Sea, Italy

Conservation actions (as Marine Protected Areas) are key tools to maintain coastal ecosystems. However, many reserves are characterized by several problems related to inadequate zonings that preclude important areas from economic activities, determining a strong hostility by local populations. Thus, estimations of marine economic values-in-use are needed for protection of marine ecosystem in order to find the best compromise between conservation priorities and local population needs. Algorithms to estimate monetary values of the main human activities in marine territories (large scale and small scale fishings, aquaculture, beach resorts, yachting, diving and commercial shipping) are here implemented using Gulf of Naples (centre Tyrrhenian sea, Italy) as study area example. These algorithms are based on different sources data (questionnaires, monitoring activities, official local authority reports, web and scientific literature). They can also be compared with each other being their outputs all expressed in the same measure unit. During the models development process a new flexible approach, called “Systematic Costs Assessment” (SCA), to assess opportunity costs in systematic conservation planning process was developed and applied. Results show that the total turnover in the Gulf of Naples is 3,950,753,487 € per year and 747,647,887 € per year excluding small scale fishing estimation, and one hectare of marine territory is worth 40,672 € and 7,696 € per year excluding small scale fishing activity. In particular, excluding small scale fishing activity, beach resort and yachting show the highest values referred to one hectare of marine territories. In conclusion, SCA is a flexible approach where no long and costly sampling campaigns are always needed, provided that two assumptions have to be taken into account, in order to estimate credible values-in-use costs: i) do not use economic activities data and ecosystem services data in the same assessment layer, since it could lead to costs overestimation and ii) SCA method are efficient when used by operators with strong knowledge of the study area, since they are able to recognize parameters affecting economic activities of local population

Seawater Acidification Affects Beta-Diversity of Benthic Communities at a Shallow Hydrothermal Vent in a Mediterranean Marine Protected Area (Underwater Archaeological Park of Baia, Naples, Italy)

One of the most important pieces of climate change evidence is ocean acidification. Acidification effects on marine organisms are widely studied, while very little is known regarding its effects on assemblages&rsquo; &beta;-diversity. In this framework, shallow hydrothermal vents within a Marine Protected Area (MPA) represent natural ecosystems acting as laboratory set-ups where the continuous carbon dioxide emissions affect assemblages with consequences that can be reasonably comparable to the effects of global water acidification. The aim of the present study is to test the impact of seawater acidification on the &beta;-diversity of soft-bottom assemblages in a shallow vent field located in the Underwater Archeological Park of Baia MPA (Gulf of Naples, Mediterranean Sea). We investigated macro- and meiofauna communities of the &lsquo;Secca delle fumose&rsquo; vent system in sites characterized by sulfurous (G) and carbon dioxide emissions (H) that are compared with control/inactive sites (CN and CS). Statistical analyses were performed on the most represented macrobenthic (Mollusca, Polychaeta, and Crustacea), and meiobenthic (Nematoda) taxa. Results show that the lowest synecological values are detected at H and, to a lesser extent, at G. Multivariate analyses show significant differences between hydrothermal vents (G, H) and control/inactive sites; the highest small-scale heterogeneities (measure of &beta;-diversity) are detected at sites H and G and are mainly affected by pH, TOC (Total Organic Carbon), and cations concentrations. Such findings are probably related to acidification effects, since MPA excludes anthropic impacts. In particular, acidification markedly affects &beta;-diversity and an increase in heterogeneity among sample replicates coupled to a decrease in number of taxa is an indicator of redundancy loss and, thus, of resilience capacity. The survival is assured to either tolerant species or those opportunistic taxa that can find good environmental conditions among gravels of sand