662 research outputs found
A polarized atomic hydrogen beam
We describe the design and operating characteristics of a simple polarized atomic hydrogen beam particularly suitable for applications to crossed beams experiments. In addition to experimental measurements, we present the results of detailed computer models, using Monte-Carlo ray tracing techniques, optical analogs, and phase-space methods, that not only provide us with a confirmation of our measurement, but also allow us to characterize the density, polarization, and atomic fraction of the beam at all points along its path. As a subsidiary result, we also present measurements of the relative and absolute efficiencies of the V/G Supavac mass analyzer for masses 1 and 2
Predictors of disease severity in children presenting from the community with febrile illnesses: a systematic review of prognostic studies.
Early identification of children at risk of severe febrile illness can optimise referral, admission and treatment decisions, particularly in resource-limited settings. We aimed to identify prognostic clinical and laboratory factors that predict progression to severe disease in febrile children presenting from the community.
We systematically reviewed publications retrieved from MEDLINE, Web of Science and Embase between 31 May 1999 and 30 April 2020, supplemented by hand search of reference lists and consultation with an expert Technical Advisory Panel. Studies evaluating prognostic factors or clinical prediction models in children presenting from the community with febrile illnesses were eligible. The primary outcome was any objective measure of disease severity ascertained within 30 days of enrolment. We calculated unadjusted likelihood ratios (LRs) for comparison of prognostic factors, and compared clinical prediction models using the area under the receiver operating characteristic curves (AUROCs). Risk of bias and applicability of studies were assessed using the Prediction Model Risk of Bias Assessment Tool and the Quality In Prognosis Studies tool.
Of 5949 articles identified, 18 studies evaluating 200 prognostic factors and 25 clinical prediction models in 24 530 children were included. Heterogeneity between studies precluded formal meta-analysis. Malnutrition (positive LR range 1.56-11.13), hypoxia (2.10-8.11), altered consciousness (1.24-14.02), and markers of acidosis (1.36-7.71) and poor peripheral perfusion (1.78-17.38) were the most common predictors of severe disease. Clinical prediction model performance varied widely (AUROC range 0.49-0.97). Concerns regarding applicability were identified and most studies were at high risk of bias.
Few studies address this important public health question. We identified prognostic factors from a wide range of geographic contexts that can help clinicians assess febrile children at risk of progressing to severe disease. Multicentre studies that include outpatients are required to explore generalisability and develop data-driven tools to support patient prioritisation and triage at the community level.
CRD42019140542
-free families in the Boolean lattice
For a family of subsets of [n]=\{1, 2, ..., n} ordered by
inclusion, and a partially ordered set P, we say that is P-free
if it does not contain a subposet isomorphic to P. Let be the
largest size of a P-free family of subsets of [n]. Let be the poset with
distinct elements a, b, c, d, a<b, c<d; i.e., the 2-dimensional Boolean
lattice. We show that where . We also prove that the largest -free
family of subsets of [n] having at most three different sizes has at most
2.20711N members.Comment: 18 pages, 2 figure
Threshold Laws for the Break-up of Atomic Particles into Several Charged Fragments
The processes with three or more charged particles in the final state exhibit
particular threshold behavior, as inferred by the famous Wannier law for (2e +
ion) system. We formulate a general solution which determines the threshold
behavior of the cross section for multiple fragmentation. Applications to
several systems of particular importance with three, four and five leptons
(electrons and positrons) in the field of charged core; and two pairs of
identical particles with opposite charges are presented. New threshold
exponents for these systems are predicted, while some previously suggested
threshold laws are revised.Comment: 40 pages, Revtex, scheduled for the July issue of Phys.Rev.A (1998
Inter-prescriber variability in the decision to prescribe antibiotics to febrile patients attending primary care in Myanmar
Background: Most antibiotic prescribing occurs in primary care. Even within the same health facility, there may be differences between prescribers in their tendency to prescribe antibiotics, which may be masked by summary data. We aimed to quantify prescriber variability in antibiotic prescription to patients with acute fever in primary care clinics in Myanmar.
Methods: We conducted a secondary analysis of prescribing data from 1090 patient consultations with 40 prescribing doctors from a trial investigating the effect of point-of-care C-reactive protein (CRP) tests on antibiotic prescription for acute fever. We used multilevel logistic regression models to assess inter-prescriber variability in the decision to prescribe antibiotics.
Results: The median odds ratio (MOR) in the unadjusted model was 1.82 (95% CI: 1.47–2.56) indicating that when two prescribers from this population are randomly selected then in half of these pairs the odds of prescription will be greater than 1.82-fold higher in one prescriber than the other. The estimated variability from this sample of prescribers corresponds to a population of prescribers where the top 25% of prescribers will prescribe antibiotics to over 41% of patients while the bottom 25% will prescribe antibiotics to less than 23% of patients. Inter-prescriber variation in antibiotic prescribing remained after adjustment for patient characteristics and CRP information (P < 0.001).
Conclusions: Despite sharing the same management guidelines, there was substantial inter-prescriber variation in antibiotic prescription to patients with acute fever. This variation should be considered when designing trials and stewardship programmes aiming to reduce inappropriate antibiotic prescribing
A Support Group for Inpatient Abused Adolescents
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75359/1/j.1744-6171.1990.tb00438.x.pd
Differential patterns of activity and functional connectivity in emotion processing neural circuitry to angry and happy faces in adolescents with and without suicide attempt
Background - Neural substrates of emotion dysregulation in adolescent suicide attempters remain unexamined. Method - We used functional magnetic resonance imaging to measure neural activity to neutral, mild or intense (i.e. 0%, 50% or 100% intensity) emotion face morphs in two separate emotion-processing runs (angry and happy) in three adolescent groups: (1) history of suicide attempt and depression (ATT, n = 14); (2) history of depression alone (NAT, n = 15); and (3) healthy controls (HC, n = 15). Post-hoc analyses were conducted on interactions from 3 group × 3 condition (intensities) whole-brain analyses (p < 0.05, corrected) for each emotion run. Results - To 50% intensity angry faces, ATT showed significantly greater activity than NAT in anterior cingulate gyral–dorsolateral prefrontal cortical attentional control circuitry, primary sensory and temporal cortices; and significantly greater activity than HC in the primary sensory cortex, while NAT had significantly lower activity than HC in the anterior cingulate gyrus and ventromedial prefrontal cortex. To neutral faces during the angry emotion-processing run, ATT had significantly lower activity than NAT in the fusiform gyrus. ATT also showed significantly lower activity than HC to 100% intensity happy faces in the primary sensory cortex, and to neutral faces in the happy run in the anterior cingulate and left medial frontal gyri (all p < 0.006,corrected). Psychophysiological interaction analyses revealed significantly reduced anterior cingulate gyral–insula functional connectivity to 50% intensity angry faces in ATT v. NAT or HC. Conclusions - Elevated activity in attention control circuitry, and reduced anterior cingulate gyral–insula functional connectivity, to 50% intensity angry faces in ATT than other groups suggest that ATT may show inefficient recruitment of attentional control neural circuitry when regulating attention to mild intensity angry faces, which may represent a potential biological marker for suicide risk
Planning for Sustainability in Small Municipalities: The Influence of Interest Groups, Growth Patterns, and Institutional Characteristics
How and why small municipalities promote sustainability through planning efforts is poorly understood. We analyzed ordinances in 451 Maine municipalities and tested theories of policy adoption using regression analysis.We found that smaller communities do adopt programs that contribute to sustainability relevant to their scale and context. In line with the political market theory, we found that municipalities with strong environmental interests, higher growth, and more formal governments were more likely to adopt these policies. Consideration of context and capacity in planning for sustainability will help planners better identify and benefit from collaboration, training, and outreach opportunities
Evolution and Impact of Bars over the Last Eight Billion Years: Early Results from GEMS
Bars drive the dynamical evolution of disk galaxies by redistributing mass
and angular momentum, and they are ubiquitous in present-day spirals. Early
studies of the Hubble Deep Field reported a dramatic decline in the rest-frame
optical bar fraction f_opt to below 5% at redshifts z>0.7, implying that disks
at these epochs are fundamentally different from present-day spirals. The GEMS
bar project, based on ~8300 galaxies with HST-based morphologies and accurate
redshifts over the range 0.2-1.1, aims at constraining the evolution and impact
of bars over the last 8 Gyr. We present early results indicating that f_opt
remains nearly constant at ~30% over the range z=0.2-1.1,corresponding to
lookback times of ~2.5-8 Gyr. The bars detected at z>0.6 are primarily strong
with ellipticities of 0.4-0.8. Remarkably, the bar fraction and range of bar
sizes observed at z>0.6 appear to be comparable to the values measured in the
local Universe for bars of corresponding strengths. Implications for bar
evolution models are discussed.Comment: Submitted June 25, 2004. 10 pages 5 figures. To appear in Penetrating
Bars through Masks of Cosmic Dust: The Hubble Tuning Fork Strikes a New Note,
eds. D. Block, K. Freeman, R. Groess, I. Puerari, & E.K. Block (Dordrecht:
Kluwer), in pres
Pertobatan Akademis
The biggest difficulty of humans cannot change or advance the quality of life is an unwillingness to change their errors and shortcomings and to repent from it. There is also willing to change but they do not change just because no action and do not really do it. There are also people who have already known that it is true, accurate, should be performed and corresponding to the norms, but still they live in sin and self-interest to ignore the interests of others. Even worse is evil (sin) is often covered in hypocrisy behind beautiful, sweet, gentle, and courteous words to make people mesmerized/hypnotized. In the case of real repentance, it should demand a match between words and actions. If there is repentance, there is a change and peace. Therefore, humans must sincerely repent and strive for it
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