95 research outputs found
ゼロギャップ半導体Ta2NiSe5における励起子絶縁体転移
学位の種別: 課程博士審査委員会委員 : (主査)東京大学教授 髙木 英典, 東京大学教授 廣井 善二, 東京大学教授 芝内 孝禎, 東京大学准教授 溝川 貴司, 東京大学准教授 山下 穣University of Tokyo(東京大学
From Ad-Hoc to Systematic: A Strategy for Imposing General Boundary Conditions in Discretized PDEs in variational quantum algorithm
We proposed a general quantum-computing-based algorithm that harnesses the
exponential power of noisy intermediate-scale quantum (NISQ) devices in solving
partial differential equations (PDE). This variational quantum eigensolver
(VQE)-inspired approach transcends previous idealized model demonstrations
constrained by strict and simplistic boundary conditions. It enables the
imposition of arbitrary boundary conditions, significantly expanding its
potential and adaptability for real-world applications, achieving this "from
ad-hoc to systematic" concept. We have implemented this method using the
fourth-order PDE (the Euler-Bernoulli beam) as example and showcased its
effectiveness with four different boundary conditions. This framework enables
expectation evaluations independent of problem size, harnessing the
exponentially growing state space inherent in quantum computing, resulting in
exceptional scalability. This method paves the way for applying quantum
computing to practical engineering applications.Comment: 16 pages, 8 figure
Calculation of Sound Insulation for Hybrid CLT Fabricated with Lumber and LVL and comparison with experimental data.
The insulated predictions were carried out for LVL, CLT and HCLT in order to evaluate their sound properties, in which the theoretical value of sound insulation was predicted by regarding the substances in wood cell wall as equivalence to specific medium based on Biot model, and the wood anatomical characteristics, such as the length and diameter of tracheid, diameter of pit, and porosity, were taken into account for determining the equivalent density and bulk modulus of elasticity of wood cell wall. By comparing the tested and predicted values of sound insulation, the conclusion were drawn as follows: the predicted values of sound insulation were significantly correlated with the tested values for LVL, CLT and HCLT. As for Masson pine and Southern pine, the adjacent of earlywood and latewood was considered as sandwich structure for the calculation of sound insulation. Meanwhile, the bonding interface was creatively introduced to improve the accuracy of sound insulation prediction. The transfer function involved in sound insulation prediction provide an effective method to characterize the sound insulation volume of wood composite in construction and decoration areas
Suppression of <i>TREX1</i> deficiency-induced cellular senescence and interferonopathies by inhibition of DNA damage response
TREX1 encodes a major DNA exonuclease and mutations of this gene are associated with type I interferonopathies in human. Mice with Trex1 deletion or mutation have shortened life spans accompanied by a senescence-associated secretory phenotype. However, the contribution of cellular senescence in TREX1 deficiency-induced type I interferonopathies remains unknown. We found that features of cellular senescence present in Trex1−/− mice are induced by multiple factors, particularly DNA damage. The cGAS-STING and DNA damage response pathways are required for maintaining TREX1 deletion-induced cellular senescence. Inhibition of the DNA damage response, such as with Checkpoint kinase 2 (CHK2) inhibitor, partially alleviated progression of type I interferonopathies and lupus-like features in the mice. These data provide insights into the initiation and development of type I interferonopathies and lupus-like diseases, and may help inform the development of targeted therapeutics
WS-Snapshot: An effective algorithm for wide-field and large-scale imaging
The Square Kilometre Array (SKA) is the largest radio interferometer under
construction in the world. The high accuracy, wide-field and large size imaging
significantly challenge the construction of the Science Data Processor (SDP) of
SKA. We propose a hybrid imaging method based on improved W-Stacking and
snapshots. The w range is reduced by fitting the snapshot plane, thus
effectively enhancing the performance of the improved W-Stacking algorithm. We
present a detailed implementation of WS-Snapshot. With full-scale SKA1-LOW
simulations, we present the imaging performance and imaging quality results for
different parameter cases. The results show that the WS-Snapshot method enables
more efficient distributed processing and significantly reduces the
computational time overhead within an acceptable accuracy range, which would be
crucial for subsequent SKA science studies.Comment: 10 pages, 10 figures, 6 tables, accepted by MNRA
Statistical Parameterized Physics-Based Machine Learning Digital Twin Models for Laser Powder Bed Fusion Process
A digital twin (DT) is a virtual representation of physical process, products
and/or systems that requires a high-fidelity computational model for continuous
update through the integration of sensor data and user input. In the context of
laser powder bed fusion (LPBF) additive manufacturing, a digital twin of the
manufacturing process can offer predictions for the produced parts, diagnostics
for manufacturing defects, as well as control capabilities. This paper
introduces a parameterized physics-based digital twin (PPB-DT) for the
statistical predictions of LPBF metal additive manufacturing process. We
accomplish this by creating a high-fidelity computational model that accurately
represents the melt pool phenomena and subsequently calibrating and validating
it through controlled experiments. In PPB-DT, a mechanistic reduced-order
method-driven stochastic calibration process is introduced, which enables the
statistical predictions of the melt pool geometries and the identification of
defects such as lack-of-fusion porosity and surface roughness, specifically for
diagnostic applications. Leveraging data derived from this physics-based model
and experiments, we have trained a machine learning-based digital twin
(PPB-ML-DT) model for predicting, monitoring, and controlling melt pool
geometries. These proposed digital twin models can be employed for predictions,
control, optimization, and quality assurance within the LPBF process,
ultimately expediting product development and certification in LPBF-based metal
additive manufacturing.Comment: arXiv admin note: text overlap with arXiv:2208.0290
- …