Age-related nomograms for antral follicle count and anti-Mullerian hormone for subfertile Chinese women in Singapore

10.1371/journal.pone.0189830PLoS ONE1212e018983

Maternal night-eating pattern and glucose tolerance during pregnancy: Study protocol for a longitudinal study

10.1136/bmjopen-2019-030036BMJ Open910e03003

Association of Cord Blood Thyroid-Stimulating Hormone Levels with Maternal, Delivery and Infant Factors

10.47102/annals-acadmedsg.2020471Annals of the Academy of Medicine, Singapore4912937 - 94

Chrononutrition during pregnancy: A review on maternal night-time eating

10.3390/nu12092783Nutrients1291 - 16GUSTO (Growing up towards Healthy Outcomes

Macronutrient composition and food groups associated with gestational weight gain: the GUSTO study

10.1007/s00394-018-1623-3European Journal of Nutrition5831081 - 1094EJNUFGUSTO (Growing up towards Healthy Outcomes

Sexually dimorphic response to feeding mode in the growth of infants

BACKGROUND: The relation between infant feeding and growth has been extensively evaluated, but studies examining sex differences in the influence of infant milk feeding on growth are limited.OBJECTIVE: We examined the interaction of infant feeding and sex in relation to infant growth and compared growth trajectories in breastfed and formula-fed boys and girls.DESIGN: In 932 infants in a Singapore mother-offspring cohort, feeding practices in the first 6 mo were classified into the breastfeeding group (BF), mixed feeding group (MF), and formula feeding group (FF). Infant weight and length were measured and converted to WHO standards for weight-for-age z scores (WAZs) and length-for-age z scores (LAZs). Differences in WAZ and LAZ from birth to 6 mo, 6 to 12 mo, and 12 to 24 mo of age were calculated. Three-way interactions were examined between feeding mode, sex, and age intervals for WAZ and LAZ changes, with adjustment for confounders.RESULTS: The interaction between feeding mode, sex, and age intervals was significant for LAZ changes (P = 0.003) but not WAZ changes (P = 0.103) after adjustment for potential confounders. Compared with BF girls, BF boys showed similar LAZ gain (+0.28 compared with +0.39, P = 0.544) from 0 to 6 mo of age but greater LAZ gain from 6 to 12 mo of age (+0.39 compared with -0.10, P = 0.008). From 0 to 6 mo of age, FF boys and girls showed greater LAZ gains than their BF counterparts; from 6 to 12 mo of age, FF girls showed higher LAZ gain (+0.25 compared with -0.10, P = 0.031) than BF girls, which was not seen in boys.CONCLUSIONS: During infancy, there is a sexually dimorphic growth response to the mode of infant milk feeding, raising questions about whether formula feeding ought to remain sex neutral. However, further investigations on sex-specific feeding and infant growth are warranted before a conclusive message can be drawn based on our current findings. This trial was registered at www.clinicaltrials.gov as NCT01174875

Association of physical activity and sedentary behaviour with depression and anxiety symptoms during pregnancy in a multi-ethnic cohort of Asian women

ObjectivesThis study aimed to investigate associations of physical activity (PA) and sedentary behavior (SB) with depression and anxiety symptoms during pregnancy among Chinese, Malay, and Indian women.MethodsWomen answered PA and SB (sitting time and television time) interview questions and self-completed the Edinburgh Postnatal Depression Scale (EPDS) and State-Trait Anxiety Inventory (STAI) questionnaires, at week 26–28 gestation. Sufficient levels of PA (?600MET-minutes/week) and higher sitting time (?7 h/day) were determined. Associations of PA and SB with probable antenatal depression (EPDS-score ?15), higher state anxiety (score ?42), and higher trait anxiety (score ?43) were determined by logistic regression analysis.ResultsAmong the 1144 pregnant women included in the study, 7.3, 22.5, and 23.6 % had probable antenatal depression, higher state anxiety, and higher trait anxiety symptoms, respectively. In the adjusted models, women with sufficient level of PA were less likely to have probable antenatal depression (OR 0.54, 95 % CI 0.31–0.94, p?=?0.030) and higher trait anxiety symptoms (OR 0.68, 95 % CI 0.48–0.94, p?=?0.022). PA was not associated with state anxiety symptoms. SB was not associated with any of the investigated outcomes.ConclusionsSufficient PA was associated with a reduced likelihood of probable antenatal depression and trait anxiety symptoms. Further investigation of these findings is warranted to determine cause-effect relationships and identify potential preventive strategies