34 research outputs found
Genome-wide association study for Atopy and Allergic Rhinitis in a Singapore Chinese population
10.1371/journal.pone.0019719PLoS ONE65
Food and Microbiota Metabolites Associate with Cognitive Decline in Older Subjects:A 12-Year Prospective Study
Apolipoprotein E and sex modulate fatty acid metabolism in a prospective observational study of cognitive decline
Apolipoprotein E and sex modulate fatty acid metabolism in a prospective observational study of cognitive decline
On the analysis of the pi -> e nu gamma experimental data
The most general amplitude for the radiative pion decay pi -> e nu gamma
including terms beyond V-A theory is considered. The experimental constraints
on the decay amplitude components are discussed. A model independent
presentation of the results of high statistics and high resolution experiments
is suggested.Comment: 5 pages, 2 figure
Coherent QCD phenomena in the Coherent Pion-Nucleon and Pion-Nucleus Production of Two Jets at High Relative Momenta
We use QCD to compute the cross section for coherent production of a di-jet
(treated as a moving at high relative transverse momentum,). In the target rest frame,the space-time evolution of this reaction is
dominated by the process in which the high component of
the pion wave function is formed before reaching the target. It then interacts
through two gluon exchange. In the approximation of keeping the leading order
in powers of and all orders in
the amplitudes for other processes are
shown to be smaller at least by a power of . The resulting dominant
amplitude is proportional to ( is the fraction
light-cone(+)momentum carried by the quark in the final state) times the skewed
gluon distribution of the target. For the pion scattering by a nuclear target,
this means that at fixed (but ) the nuclear process in which there is only a single interaction is the
most important one to contribute to the reaction. Thus in this limit color
transparency phenomena should occur.These findings are in accord with E971
experiment at FNAL. We also re-examine a potentially important nuclear multiple
scattering correction which is positive and . The
meaning of the signal obtained from the experimental measurement of pion
diffraction into two jets is also critically examined and significant
corrections are identified.We show also that for values of achieved
at fixed target energies, di-jet production by the e.m. field of the nucleus
leads to an insignificant correction which gets more important as
increases.Comment: 23 pages, 9 figure
Exploration of the Gut-Brain Axis through Metabolomics Identifies Serum Propionic Acid Associated with Higher Cognitive Decline in Older Persons
Impaired hippocampal neurogenesis in vitro is modulated by dietary-related endogenous factors and associated with depression in a longitudinal ageing cohort study
The serum metabolome mediates the concert of diet, exercise, and neurogenesis, determining the risk for cognitive decline and dementia
The serum metabolome mediates the concert of diet, exercise, and neurogenesis, determining the risk for cognitive decline and dementia
Introduction: Diet and exercise influence the risk of cognitive decline (CD) and dementia through the food metabolome and exercise-triggered endogenous factors, which use the blood as a vehicle to communicate with the brain. These factors might act in concert with hippocampal neurogenesis (HN) to shape CD and dementia. Methods: Using an in vitro neurogenesis assay, we examined the effects of serum samples from a longitudinal cohort (n = 418) on proxy HN readouts and their association with future CD and dementia across a 12-year period. Results: Altered apoptosis and reduced hippocampal progenitor cell integrity were associated with exercise and diet and predicted subsequent CD and dementia. The effects of exercise and diet on CD specifically were mediated by apoptosis. Discussion: Diet and exercise might influence neurogenesis long before the onset of CD and dementia. Alterations in HN could signify the start of the pathological process and potentially represent biomarkers for CD and dementia