Ultrasonic treatments during the alcoholic fermentation of red wines: effects on 'Syrah' wines

Grapes grown in warm climates have shorter ripening periods. This makes the regular level of several compounds related to sensory properties in wine to remain low. Therefore, those grapes need to receive a particular treatment during winemaking processes if they have to reach the adequate content levels of colour and aroma related compounds. Applying ultrasound during some of the winemaking procedures may contribute to improving the maceration process, which would result in a higher recovery of compounds from grape skins and seeds to the must. This work studies the effect of applying ultrasound to 'Syrah' musts for two different time lengths during its alcoholic fermentation. The wines produced according to regular winemaking procedures (reference wines) were then compared to wines that had been produced under the effect of ultrasound for 30 to 60 min per day. The results showed that the wines produced using ultrasound had concentrations of volatile compounds higher than their reference wine. These data were consistent with the results from the tasting panel, where the judges highlighted the red fruit notes of the wines resulting from the application of ultrasound during the alcoholic fermentation. On the other hand, there were differences between the two wines resulting from applying ultrasound for two different lengths of time, applying ultrasound for 30 min per day proved to be more effective in terms of aroma than applying ultrasounds for 60 min per day. The conclusion of this research is that applying ultrasound during the alcoholic fermentation favours the extraction of volatile compounds. However different times can produce different results. Furthermore, an excessive application of ultrasound may lead to the degradation of some of the compounds of interest

Epidemiological and clinical features of Kawasaki disease in Spain over 5 years and risk factors for aneurysm development. (2011-2016): KAWA-RACE study group

BACKGROUND: Kawasaki disease (KD) is an acute self-limited systemic vasculitis of unknown etiology affecting mainly children less than 5 years of age. Risk factors for cardiac involvement and resistance to treatment are insufficiently studied in non-Japanese children. OBJECTIVE: This study aimed to investigate the epidemiology, clinical features and risk factors for resistance to treatment and coronary artery lesions (CAL) in KD in Spain. METHODS: Retrospective study (May 2011-June 2016) of all patients less than 16 years of age diagnosed with KD included in KAWA-RACE network (84 Spanish hospitals). RESULTS: A total of 625 cases were analyzed, 63% were males, 79% under 5 year-olds and 16.8% younger than 12 months. On echocardiographic examination CAL were the most frequent findings (23%) being ectasia the most common (12%). Coronary aneurysms were diagnosed in 9.6%, reaching 20% in infants under 12 months (p 900,000 cells/mm3, maximum temperature 10 days and fever before treatment >/= 8 days as independent risk factors for developing coronary aneurysms. CONCLUSIONS: In our population, children under 12 months develop coronary aneurysms more frequently and children with KD with anemia and leukocytosis have high risk of cardiac involvement. Adding steroids early should be considered in those patients, especially if the treatment is not started before 8 days of fever. A score applicable to non-Japanese children able to predict the risk of aneurysm development and IVIG resistance is necessary