4 research outputs found

    Uji Aktivitas Antiinflamasi Ekstrak Etanol Daun Tumbuhan Akar Kaik-Kaik (Uncaria cordata (Lour.) Merr) Terhadap Tikus Putih (Rattus norvegicus) Jantan

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    The study has been carried out of antiinflammatory activity of ethanol extract leaves of plant akar kaik-kaik (Uncaria cordata (Lour.) Merr of the male white rat (Rattus norvegicus). The ethanol extract was first conducted quality checks extracts include: organoleptic test, Thin Layer Chromatography profiles (TLC), determination of water content, drying shrinkage, and ash content. The results showed the ethanol extract the requirements extracts in general. Further test antiinflammatory activity of the white rat (Rattus norvegicus) males using the paw edema. Animal trials were divided into 5 groups: negative control group Na CMC 1%, a positive control diclofenac sodium 4.5 mg/kg weight of the rat and the ethanol extract dose of 100, 200, and 400 mg/kg weight of the rat, the rats are challenged by a subcutaneous injection of 1% solution of carrageenan into the plantar side of the left hind paw, result showed that the ethanol extract doses of 100, 200 and 400 mg/kg weight of the rat had a significantly antiinflammatory activity  (p <0.05). &nbsp

    Uji Aktivitas Antiinflamasi Ekstrak Etil Asetat Daun Tumbuhan Akar Kaik-Kaik (Uncaria cordata (Lour.) Merr) pada Tikus Putih (Rattus norvegicus) Jantan

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    Antiinflammatory activity of ethyl acetate extracts of the leaves of plant Akar Kaik-kaik Uncaria cordata (Lour.) Merr on white male rats. This research examined the quality of crude drugs and extracts ethyl acetate. It is intended to obtain raw materials which can ultimately ensure uniform pharmacologic effect.  Antiinflammatory activity of the ethyl acetate extract were tested using the method of paw edema against white male rats. The research were 15 rats mile which divided into 5 groups. Negative control (Na CMC 1%), positive control (Na diklofenak dose 4,5 mg/kgBB) and extract group ethyl acetat with the dose 100, 200 and 400 mg/kgBB given orally. The volume measurement after subcutaneous injection caragen 1% performed with one hour interval for 5 hours assessing with pletysmometer and calculated the inhibition persen. The result of this study showed that the quality of crude drugs and extract ethyl acetate meet the specified requirements Indonesian Herbal Pharmacopoeia. Ethyl acetate extract has significant anti-inflammatory effects to the negative control at doses of 200 and 400 mg/kgBB while against the positive control did not differ significantly white male rats

    SEMINAR TENTANG PELEMBAB KULIT WAJAH DARI EKSTRAK DAUN NANGKA (ATROCARPUS HETEROPHYLLUS LAM.)

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    One of the Indonesia plant has the potential to produce a natural antioxidannt is nangka leaf containing flavonoids,saponins, tannins.objectives: tomake preparations creamy nangka leaf extract mask. Method the study was conducted experimentally,the sampelwas extracted by maceration for 3x24 hours using 96% ethanol. The results of the viscous extract is obtained as the active substances with concentrations 5% and 10%. Test preparations test organoleptis, include an examination of its homogeneity, ph preparations and skin moisture. Homogeneity test showed that the mask cream preparations produced were homogeneous, pH range 6-7 and the humidity test with a concentration of 5% obtained an average value and could moisturize the skin and a concentration of 10% obtained an average value of 59.46% could moisturize the skin. Jackfruit leaf extract can be formulated in cream mask preparations and cream jackfruit leaf mask extract preparations can moisturize the skin
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