Dipole Fringe Field Effects in the ThomX Ring

WEPEA003 - work is supported by the French "Agence Nationale de la Recherche" as part of the program "investing in the future" under reference ANR-10-EQPX-51, and also by grants from Region Ile-de-France.International audienceThom-X is a 50MeV compact ring based on the Compton back-scattering which is being built in LAL, France. With a very short bend radius of 0.352 m, the nonlinear effects of the dipole fringe fields become critical to the beam dynamic . This paper compares the modelings of the dipole fringe field using four popular codes: MadX, Elegant, BETA, and Tracy3, and then discuss the proper model to have consistent results between the analytical calculation and the symplectic tracking of the Thom-X ring

Automatic Optimization of Python Skeletal Parallel Programs

International audienceSkeletal parallelism is a model of parallelism where parallel constructs are provided to the programmer as usual patterns of parallel algorithms. High-level skeleton libraries often offer a global view of programs instead of the common Single Program Multiple Data view in parallel programming. A program is written as a sequential program but operates on parallel data structures. Most of the time, skeletons on a parallel data structure have counterparts on a sequential data structure. For example, the map function that applies a given function to all the elements of a sequential collection (e.g., a list) has a map skeleton counterpart that applies a sequential function to all the elements of a distributed collection. Two of the challenges a programmer faces when using a skeleton library that provides a wide variety of skeletons are: which are the skeletons to use, and how to compose them? These design decisions may have a large impact on the performance of the parallel programs. However, skeletons, especially when they do not mutate the data structure they operate on, but are rather implemented as pure functions , possess algebraic properties that allow to transform compositions of skeletons into more efficient compositions of skeletons. In this paper, we present such an automatic transformation framework for the Python skeleton library PySke and evaluate it on several example applications

PySke: Algorithmic Skeletons for Python

International audiencePySke is a library of parallel algorithmic skeletons in Python designed for list and tree data structures. Such algorithmic skeletons are high-order functions implemented in parallel. An application developed with PySke is a composition of skeletons. To ease the write of parallel programs, PySke does not follow the Single Program Multiple Data (SPMD) paradigm but offers a global view of parallel programs to users. This approach aims at writing scalable programs easily. In addition to the library, we present experiments performed on a high-performance computing cluster (distributed memory) on a set of example applications developed with PySke

ARC-EN-CIEL beam dynamics

MOPC023International audienceARC-EN-CIEL project is based on a CW 1.3 GHz superconducting (SC) linac accelerator delivering high charge, subpicosecond and low emittance electron bunches at high repetition rate [1]. According to the electron energy, it provides tunable light sources of high brightness in the VUV to soft X-ray wavelength domain. The project will evolve into three phases: first and second phases are based on high brightness single pass SC linac configuration with a low average current (few µA), while third phase integrates recirculation loops to increase the average current (up to 100 mA)

Effect of Beam Dynamics Processes in the Low Energy Ring ThomX

As part of the R\&D for the 50 MeV ThomX Compton source project, we have studied the effect of several beam dynamics processes on the evolution of the beam in the ring. The processes studied include among others Compton scattering, intrabeam scattering, coherent synchrotron radiation. We have performed extensive simulations of a full injection/extraction cycle (400000 turns). We show how each of these processes degrades the flux of photons produced and how a feedback system contributes to recovering most of the flux.Comment: Submitted to IPAC'14, WEPRO00

Prevalence of mixed genotype hepatitis C virus infections in the UK as determined by genotype‐specific PCR and deep sequencing

The incidence of mixed genotype hepatitis C virus infections in the UK is largely unknown. As the efficacy of direct acting antivirals is variable across different genotypes, treatment regimens are tailored to the infecting genotype, which may pose issues for the treatment of underlying genotypes within undiagnosed mixed genotype HCV infections. There is therefore a need to accurately diagnose mixed genotype infections prior to treatment. PCR-based diagnostic tools were developed to screen for the occurrence of mixed genotype infections caused by the most common UK genotypes, 1a and 3, in a cohort of 506 individuals diagnosed with either of these genotypes. The overall prevalence rate of mixed infection was 3.8% however this rate was unevenly distributed, with 6.7% of individuals diagnosed with genotype 3 harbouring genotype 1a strains and only 0.8% of samples from genotype 1a patients harbouring genotype 3 (p<0.05). Mixed infection samples consisted of a major and a minor genotype, with the latter constituting less than 21% of the total viral load and, in 67% of cases, less than 1% of the viral load. Analysis of a subset of the cohort by Illumina PCR-next generation sequencing resulted in a much greater incidence rate than obtained by PCR. This may have occurred due to the non-quantitative nature of the technique and despite the designation of false positive thresholds based on negative controls

Electron Beam Dynamics in the 50 MeV ThomX Compact Storage Ring

International audienceThomX is a high flux compact X-ray source based on Compton back scattering between a relativistic electron beam and an intense laser pulse. To increase the repetition rate, the electron beam is stored in a ring. The main drawback of such a scheme is the low energy of the electrons regarding collective effects and intrabeam scattering. These effects tend to enlarge or even disrupt the stored bunch and they limit its charge, especially in a system where damping plays a negligible role. Thus such collective effects reduce the maximum X-ray flux and it is important to investigate them to predict the performance of this type of X-ray source. In addition, the Compton back scattering acts on the electron beam by increasing its energy spread. This presentation will show firstly the impact of collective effects on the electron beam, essentially during the first turns when they are the most harmful. Then, the reduction of the X-ray flux due to Compton back scattering and intrabeam scattering will be investigated on a longer time scale