Spacelike Mean Curvature Flow

We prove long-time existence and convergence results for spacelike solutions to mean curvature flow in the pseudo-Euclidean space Rn,m, which are entire or defined on bounded domains and satisfying Neumann or Dirichlet boundary conditions. As an application, we prove long-time existence and convergence of the G2-Laplacian flow in cases related to coassociative fibrations

Uniqueness of Lagrangian self-expanders

In mean curvature flow an important class of solutions are the self-expanders, which move simply by dilations under the flow and provide models for smoothing of singular con- figurations. In K¨ahler–Einstein manifolds mean curvature flow preserves Lagrangian submanifolds,providing the notion of Lagrangian mean curvature flow. I will describe joint work with Neves [12] showing that Lagrangian self-expanders in Cn asymptotic to pairs of planes are locally unique if n > 2 and unique if n = 2

The space of hyperkähler metrics on a 4-manifold with boundary

Let X be a compact 4-manifold with boundary. We study the space of hyperk¨ahler triples ω1, ω2, ω3 on X, modulo diffeomorphisms which are the identity on the boundary. We prove that this moduli space is a smooth infinite-dimensional manifold and describe the tangent space in terms of triples of closed anti-self-dual 2-forms. We also explore the corresponding boundary value problem: a hyperk¨ahler triple restricts to a closed framing of the bundle of 2-forms on the boundary; we identify the infinitesimal deformations of this closed framing that can be filled in to hyperk¨ahler deformations of the original triple. Finally we study explicit examples coming from gravitational instantons with isometric actions of SU(2)

SU(2)² -invariant G₂ -instantons

We initiate the systematic study of G₂-instantons with SU(2)² -symmetry. As well as developing foundational theory, we give existence, non-existence and classification results for these instantons. We particularly focus on R⁴ x S³ with its two explicitly known distinct holonomy G₂ metrics, which have different volume growths at infinity, exhibiting the different behaviour of instantons in these settings. We alsogive an explicit example of sequences of G₂-instantons where “bubbling” and “removable singularity” phenomena occur in the limit

A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

Meeting abstrac

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHRadjBMI), a measure of body shape. Body size and shape change as people grow older and these changes differ substantially between men and women. To systematically screen for age-and/or sex-specific effects of genetic variants on BMI and WHRadjBMI, we performed meta-analyses of 114 studies (up to 320,485 individuals of European descent) with genome-wide chip and/or Metabochip data by the Genetic Investigation of Anthropometric Traits (GIANT) Consortium. Each study tested the association of up to similar to 2.8M SNPs with BMI and WHRadjBMI in four strata (men &lt;= 50y, men &gt; 50y, women &lt;= 50y, women &gt; 50y) and summary statistics were combined in stratum-specific meta-analyses. We then screened for variants that showed age-specific effects (G x AGE), sex-specific effects (G x SEX) or age-specific effects that differed between men and women (G x AGE x SEX). For BMI, we identified 15 loci (11 previously established for main effects, four novel) that showed significant (FDR&lt; 5%) age-specific effects, of which 11 had larger effects in younger (&lt; 50y) than in older adults (&gt;= 50y). No sex-dependent effects were identified for BMI. For WHRadjBMI, we identified 44 loci (27 previously established for main effects, 17 novel) with sex-specific effects, of which 28 showed larger effects in women than in men, five showed larger effects in men than in women, and 11 showed opposite effects between sexes. No age-dependent effects were identified for WHRadjBMI. This is the first genome-wide interaction meta-analysis to report convincing evidence of age-dependent genetic effects on BMI. In addition, we confirm the sex-specificity of genetic effects on WHRadjBMI. These results may providefurther insights into the biology that underlies weight change with age or the sexually dimorphism of body shape.</p

Examples of equivariant Lagrangian mean curvature flow

In this expository note we describe important examples of Lagrangian mean curvature flow in $\mathbb{C}^2$ which are invariant under a circle action. Through these examples, we see compact and non-compact situations, long-time existence, singularities forming via explicit models, and significant objects in Riemannian and symplectic geometry, including the Clifford torus, Chekanov torus, Whitney sphere and Lawlor necks

Laplacian flow for closed G2 structures: Shi-type estimates, uniqueness and compactness

We develop foundational theory for the Laplacian flow for closed G2 structures which will be essential for future study. (1). We prove Shi-type derivative estimates for the Riemann curvature tensor Rm and torsion tensor T along the flow, i.e. that a bound on Λ(x,t)=(|∇T(x,t)|2g(t)+|Rm(x,t)|2g(t))12 will imply bounds on all covariant derivatives of Rm and T. (2). We show that Λ(x,t) will blow up at a finite-time singularity, so the flow will exist as long as Λ(x,t) remains bounded. (3). We give a new proof of forward uniqueness and prove backward uniqueness of the flow, and give some applications. (4). We prove a compactness theorem for the flow and use it to strengthen our long time existence result from (2) to show that the flow will exist as long as the velocity of the flow remains bounded. (5). Finally, we study soliton solutions of the Laplacian flow

Stability of torsion-free G_2 structures along the Laplacian flow

We prove that torsion-free G_2 structures are (weakly) dynamically stable along the Laplacian flow for closed G_2 structures. More precisely, given a torsion-free G_2 structure $\varphi$ on a compact 7-manifold, the Laplacian flow with initial value cohomologous and sufficiently close to $\varphi$ will converge to a torsion-free G_2 structure which is in the orbit of $\varphi$ under diffeomorphisms isotopic to the identity

Geometric flows of G2-structures on 3-Sasakian 7-manifolds

A 3-Sasakian structure on a 7-manifold may be used to define two distinct Einstein metrics: the 3-Sasakian metric and the squashed Einstein metric. Both metrics are induced by nearly parallel G2-structures which may also be expressed in terms of the 3-Sasakian structure. Just as Einstein metrics are critical points for the Ricci flow up to rescaling, nearly parallel G2-structures provide natural critical points of the (rescaled) geometric flows of G2-structures known as the Laplacian flow and Laplacian coflow. We study each of these flows in the 3-Sasakian setting and see that their behaviour is markedly different, particularly regarding the stability of the nearly parallel G2-structures. We also compare the behaviour of the flows of G2-structures with the (rescaled) Ricci flow.</p