15 research outputs found
Gold Nanoparticle Decorated Carbon Nanopipettes for Intracellular SERS
Single cell analysis is an increasingly important factor for understanding fundamental cellular functions at the molecular level. As a label-free technique capable of measuring multiple molecules simultaneously, surface enhanced Raman spectroscopy (SERS) is an ideal candidate for miniaturization to the cellular level. Current SERS-active probe designs are limited by their size, fabrication difficulty, or background signal derived from functionalization. In this work, a protocol for batch fabrication of residue-free gold nanoparticle decorated carbon nanopipettes was developed. SERS-activity of the decorated nanopipettes was demonstrated on droplets of 1 mM glycine. The stability of the attached nanoparticles was confirmed in vivo by interrogation of living cells. Moreover, identification of several key factors related to particle growth will provide an avenue for future optimization of particle size and coverage.M.S., Materials Science and Engineering -- Drexel University, 201
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‘A new occasion, a new term of relation’: Samuel Beckett and T. S. Eliot
This essay examines the understudied relationship between T. S. Eliot and Samuel Beckett. In the first part of this essay, previous critical treatments of this relationship are considered and factual corrections are made where error has been introduced regarding remarks by Beckett on Eliot. This essay then explores Beckett’s treatment of what he identifies as two distinct versions of Eliot: the early twentieth-century experimental writer of such poems as The Waste Land; and the critic-publisher of The Criterion, Faber & Faber, and the producer of what Beckett labelled a ‘professorial’ approach to poetry. In doing so, this essay considers how the conflicts between Beckett’s rejection of Eliot as a critic and his more ambivalent treatment of Eliot as a poet allow for an exploration of the tensions that are central to modernism, and how this impacts the configuration of both Eliot and Beckett within what has come to be thought of as ‘Late Modernism’