159 research outputs found
Neurological outcome of newborns with neonatal seizures: a cohort study in a tertiary university hospital
Valor do EEG na caracterização e prognóstico de patologias neurológicas em recém-nascidos prematuros
Prognostic value of non-reactive burst suppression EEG pattern associated to early neonatal seizures
Recomendações para o registro/interpretação do mapeamento topográfico do eletrencefalograma e potenciais evocados: Parte II: Correlações clínicas
Relevance of Basic Research to Clinical Data: Good Answers, Wrong Questions!
Do early seizures beget seizures later in life? Clinical data and experimental observations seem to answer that question differently, with a no and a yes, respectively, which may stem from an inadequate readout of what experimental data actually do tell us and a possible simplification of what clinical data indicate. Using specific experimental examples, it is possible to show that in the developing brain, seizures do produce long-lasting alterations of neuronal excitability, although ongoing seizures are not observed in adults. The findings suggest that the long-lasting changes in developmental programs and network activity that seizures induce do not necessarily lead to epilepsy, unless other events that remain to be identified occur
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