Immunological Study of CD34 Positive Stem Cells in Cord Blood

Abstract: Problem statement: The Cluster of differentiation CD34 molecule is present on certain cells within the human body .It mediate attachment of stem cells to bone marrow extra cellular matrix or directly to stromal cells. Approach: In this study we studied the amount of expression of CD34 on cord blood stem cells in babies of normal healthy pregnant females and in unhealthy conditions as diabetes. Materials and methods; the count of CD34 + cells was assessed by flow cytometric analysis. Results: There was statistically significant difference between the count of CD34 + cellsin the cord blood. The count was higher with normal vaginal delivery, heavier infants and higher leukocytic count, a significant reduction in the count of CD34 + cells in the diabetic group. Key words: Significant reduction, diabetic group, human embryonic stem, mediate attachment, embryonic membranes, developed organism Abbreviation:(CD) cluster of differentiation