Analyzing the Restoration of the Oklahoma State Capitol from the Perspective of the Design Build Process:a Descriptive Case Study

Design Build projects in the built environment are moving towards more collaborative practices. The intent behind this collaborative approach is to encourage those associated with the built environment to consider how retrofit design and construction can contribute positively to addressing elements of climate change and the design build process. The opportunity to share the rich nature of the design build process in a unique environmentally and heritage focused project excited the authors. Secondly concerns about the way such projects are captured historically, and specifically the disciplinary knowledge and skills employed in the restoration of such a significant landmark building could be lost if not afforded some place in the research annals. This paper presents a Restoration Design-Build (RDB) process employed in the realignment of a state building adopting this novel initiative. The authors adopted a descriptive case study method to enhance the capabilities of understanding and generate constructive reflections and analysis. The intention was to empower the reader to explore new horizons by ‘clarifying and negotiating’ ideas and concerns around the RDB process. The authors evaluated the usefulness of the RDB approach based on direct and indirect measures. The framework approach presented is a part of an ongoing initiative between state and project stakeholders that have shown positive results based on the teams’ performance in the presented case study as well as affirmative feedback from some stakeholder participants

An analysis of running injuries at Vancouver Sun Run In Training clinics

Objective: To provide an analysis of running injuries among those participating in Sun Run InTraining clinics during 2000 and 2001. Method: Two different questionnaires were developed for InTraining clinic participants. These assessed participants’ fitness, their running routines, and their injury history. One questionnaire was administered in 2000 and the other in2001. Results: Overall, 31.6% of the 1265 respondents were classified as injured during the study period. The knee was the most frequently injured area. In 2000, one-half of injured runners had experienced a running injury in the past. In 2001, the level of rehabilitation from previous injuries accounted for 90.1% of the explained variation in our training function score (TFS), with the remainder explained by differences in self-assessed physical fitness. Conclusion: Runners who consider themselves unfit and have a history of injury should understand that they face an increased likelihood of experiencing a running injury

Mucociliary clearance in COPD can be increased by both a D2/β2 and a standard β2 agonists

SummaryIn addition to breathlessness and cough, excessive mucus production is one of the main symptoms of chronic obstructive pulmonary disease (COPD). Excess mucus coupled with deteriorating mucociliary clearance is associated with a decline in lung function and an increased risk of death from pulmonary infection. The effect of ViozanTM (Sibenadet HCI, AR-C68397AA), a novel dual D2 dopamine receptor, β2-adrenoceptor agonist, on mucociliary clearance was investigated together with that of a β2-adrenoceptor agonist, salbutamol. Using a double blind, parallel group study design, 15 patients with COPD, all habitual smokers, were randomised to receive nebulised sidenadet (3mg tid; n=7) or salbutamol (5mg tid; n=8) for 10 days. Lung mucociliary clearance rates were measured, by a standard radioaerosol technique, before and after the treatment period, as were 24-h sputum volumes. Both sibenadet and salbutamol therapies resulted in significant (P<0.02) enhancement of lung mucociliary clearance. The 24-h sputum volume was significantly reduced following sibenadet therapy (P<0.03) whereas salbutamol therapy had no effect. Our results, in addition to illustrating the effects of a standard β2 agonist on mucociliary clearance, strongly suggest the potential dual benefit of dual-agonist compounds in lessening sputum production whilst simultaneously enhancing mucociliary clearance. For reasons unconnected with the present study, development work on this specific formulation is no longer proceeding

Universal quantum interfaces

To observe or control a quantum system, one must interact with it via an interface. This letter exhibits simple universal quantum interfaces--quantum input/output ports consisting of a single two-state system or quantum bit that interacts with the system to be observed or controlled. It is shown that under very general conditions the ability to observe and control the quantum bit on its own implies the ability to observe and control the system itself. The interface can also be used as a quantum communication channel, and multiple quantum systems can be connected by interfaces to become an efficient universal quantum computer. Experimental realizations are proposed, and implications for controllability, observability, and quantum information processing are explored.Comment: 4 pages, 3 figures, RevTe

Clifford algebras and universal sets of quantum gates

In this paper is shown an application of Clifford algebras to the construction of computationally universal sets of quantum gates for $n$-qubit systems. It is based on the well-known application of Lie algebras together with the especially simple commutation law for Clifford algebras, which states that all basic elements either commute or anticommute.Comment: 4 pages, REVTeX (2 col.), low-level language corrections, PR

Coregistering functional near-infrared spectroscopy with underlying cortical areas in infants

Functional near-infrared spectroscopy (fNIRS) is becoming a popular tool in developmental neuroscience for mapping functional localized brain responses. However, as it cannot provide information about underlying anatomy, researchers have begun to conduct spatial registration of fNIRS channels to cortical anatomy in adults. The current work investigated this issue with infants by coregistering fNIRS and magnetic resonance imaging (MRI) data from 55 individuals. Our findings suggest that fNIRS channels can be reliably registered with regions in the frontal and temporal cortex of infants from 4 to 7 months of age. Although some macro-anatomical regions are difficult to consistently define, others are more stable and fNIRS channels on an age-appropriate MRI template are often consistent with individual infant MRIs. We have generated a standardized scalp surface map of fNIRS channel locators to reliably locate cortical regions for fNIRS developmental researchers. This new map can be used to identify the inferior frontal gyrus, superior temporal sulcus (STS) region [which includes the superior and middle temporal gyri (MTG) nearest to the STS], and MTG and temporal-parietal regions in 4- to 7-month-old infants. Future work will model data for the whole head, taking into account the properties of light transport in tissue, and expanding to different ages across development