The Grizzly, October 8, 2009

Weather Cooperates for 2009 Homecoming • Honing in on Housing • Berman Museum Opens New Watercolor Exhibit • SIFE Organizes Women in Business Panel for Students • Hidden Enthusiasts Come Together to Form Comic Book Culture at UC • Dining Services Receives a Makeover in and out of the Kitchen • UC United Brings Strength in Numbers • Athletic Department Seeks New AD, Moliken Stands In • Gentlemen and Scholars: Ursinus Men\u27s Rugby 2009https://digitalcommons.ursinus.edu/grizzlynews/1794/thumbnail.jp

The Grizzly, January 29, 2004

Myrin Library is Hit with Catastrophe • Myrin Library Water Damage: Photo Essay • Kerry Led in Iowa Caucuses • Opinions: Ursinus Greeks vs. Pop Culture; Farewell to E-Follett; Winter Weathered Out • Iowa Caucus Results • New Theater Production Sure to be a Hit! • Ursinus College Leadership Studies Program • Students Meet with Wynton Marsalis • A Prime Example of a Team Leader • UC Wrestling Recognizedhttps://digitalcommons.ursinus.edu/grizzlynews/1551/thumbnail.jp

The Grizzly, May 5, 2011

Student Found to be Bone Marrow Match • UC Students Show Off Their Real Bodies in Fashion Show • Ursinus College Environmental Action Hosts Earth Week • Breakaway Student Productions Presents One Act Plays • Osama bin Laden Announced Dead • POD Participates in Creek Clean-up • Senior Spotlight: Looking Towards New Adventures • Saying Farewell after Four Years at Ursinus College • Senior Reflection • Looking Forward to Warm Weather • Opinions: Putting End of Semester Finals into Perspective; Main Street Drivers not Winning and not Appealing • Men and Women\u27s Track & Field Ends on High Note • UC Baseball and Softball Playoff Runs Come to a Closehttps://digitalcommons.ursinus.edu/grizzlynews/1837/thumbnail.jp

The Grizzly, March 25, 2010

27th Annual Airband Benefits Dignity House • Ursinus College Theater Presents The Elephant Man • Bank Robber Flees to Ursinus Campus Parking Lot • InterVarsity Group Travels to Camden Over Spring Break • Dangerous Risk to Multi-Tasking • Ursinus Field Hockey Intramurals are Open for Spring • UC Baseball Makes Best of Florida Trip • UC Alum Coaches Cornell to Sweet 16https://digitalcommons.ursinus.edu/grizzlynews/1809/thumbnail.jp

The Grizzly, February 4, 2010

The Brandon Kamin Show Premieres • Students Leading Haiti Relief Initiatives • Berman Premieres Min(d)ing the Landscape Exhibit • Ursinus Alumnus, J. D. Salinger, Dies • TCE Air Monitoring: Ursinus Student Research with the DEP • Learning to Learn: Choosing Majors and Finding a Path at Ursinus College • Opinion: Student Perceptions of CIE: What do Students Take from Course? • Ursinus Men\u27s Rugby Looking Forward to 2010https://digitalcommons.ursinus.edu/grizzlynews/1804/thumbnail.jp

The Grizzly, December 10, 2009

Escape Velocity Performs Winter Show: Celebrate! • Management Teams Tally Up Their Profits • Sustainability: Dreaming of a Green Christmas • Ursinus Hosts America Reads for the Tenth Annual Holiday Celebration • UC United Brings Inspirational Speaker Nancy Hunter Denney to Ursinus • Dangerous Effects of Tanning Beds • New Mammogram Recommendations • Bizarre Foods: The Fabulous Five Dollar Festive Feast • Opinion: Present Your Partner with the Perfect Present: Holiday Gift Ideas • Breaking School Records and Then Somehttps://digitalcommons.ursinus.edu/grizzlynews/1802/thumbnail.jp

The Grizzly, March 4, 2010

Ursinus Theater presents The Crucible • Political Cartoonist, Author Discusses New Book • CoSA Application, Logo Submission Deadlines Extended • Interest in Bioethics in Medicine Rises at UC • American Heart Month • Ursinus Looks Into The Buried Life • Neshoba Highlights Civil Rights Corruption in Honor of Black History Month • Chat Roulette Gambles with the Issues of Social Networking • Ursinus Lacrosse Looks to Outwork Opposition • Indoor Track & Field Championshiphttps://digitalcommons.ursinus.edu/grizzlynews/1808/thumbnail.jp

The Grizzly, October 1, 2009

Students Composting to Create Sustainability • Students Fight the Yawn and Stay Up \u27Til Dawn • Former NY Times Editor Gives Students Advice • Unsolved Vandalism on Campus Could Hit Students\u27 Wallets • Dissatisfaction Erupts with Mass E-mail • Teaching Assistants Indulge in the UC Culture • Beatles Enthusiast\u27s Book Tour Hits Phoenixville • First to Perform Original Play in 100 Years • Opinions: Freedom of Expression?: Pornography Trial; Play Review: A Wise Choice for Weekend Amusement; Liar, Liar, President Obama\u27s Plans May Catch on Fire ; How About a Universal Care-for-Your-Health Plan?: Employer Health Incentives • Ursinus Women\u27s Lacrosse Welcomes New Assistant Coach • UCXC Continues Their Long Strides in 2009https://digitalcommons.ursinus.edu/grizzlynews/1793/thumbnail.jp

Ten-year mortality, disease progression, and treatment-related side effects in men with localised prostate cancer from the ProtecT randomised controlled trial according to treatment received

Background The ProtecT trial reported intention-to-treat analysis of men with localised prostate cancer randomly allocated to active monitoring (AM), radical prostatectomy, and external beam radiotherapy. Objective To report outcomes according to treatment received in men in randomised and treatment choice cohorts. Design, setting, and participants This study focuses on secondary care. Men with clinically localised prostate cancer at one of nine UK centres were invited to participate in the treatment trial comparing AM, radical prostatectomy, and radiotherapy. Intervention Two cohorts included 1643 men who agreed to be randomised and 997 who declined randomisation and chose treatment. Outcome measurements and statistical analysis Analysis was carried out to assess mortality, metastasis and progression and health-related quality of life impacts on urinary, bowel, and sexual function using patient-reported outcome measures. Analysis was based on comparisons between groups defined by treatment received for both randomised and treatment choice cohorts in turn, with pooled estimates of intervention effect obtained using meta-analysis. Differences were estimated with adjustment for known prognostic factors using propensity scores. Results and limitations According to treatment received, more men receiving AM died of PCa (AM 1.85%, surgery 0.67%, radiotherapy 0.73%), whilst this difference remained consistent with chance in the randomised cohort (p = 0.08); stronger evidence was found in the exploratory analyses (randomised plus choice cohort) when AM was compared with the combined radical treatment group (p = 0.003). There was also strong evidence that metastasis (AM 5.6%, surgery 2.4%, radiotherapy 2.7%) and disease progression (AM 20.35%, surgery 5.87%, radiotherapy 6.62%) were more common in the AM group. Compared with AM, there were higher risks of sexual dysfunction (95% at 6 mo) and urinary incontinence (55% at 6 mo) after surgery, and of sexual dysfunction (88% at 6 mo) and bowel dysfunction (5% at 6 mo) after radiotherapy. The key limitations are the potential for bias when comparing groups defined by treatment received and changes in the protocol for AM during the lengthy follow-up required in trials of screen-detected PCa. Conclusions Analyses according to treatment received showed increased rates of disease-related events and lower rates of patient-reported harms in men managed by AM compared with men managed by radical treatment, and stronger evidence of greater PCa mortality in the AM group. Patient summary More than 95 out of every 100 men with low or intermediate risk localised prostate cancer do not die of prostate cancer within 10 yr, irrespective of whether treatment is by means of monitoring, surgery, or radiotherapy. Side effects on sexual and bladder function are better after active monitoring, but the risks of spreading of prostate cancer are more common