Electroweak Beautygenesis: From b {\to} s CP-violation to the Cosmic Baryon Asymmetry

We address the possibility that CP-violation in $B_s-\bar B_s$ mixing may help explain the origin of the cosmic baryon asymmetry. We propose a new baryogenesis mechanism - "Electroweak Beautygenesis" - explicitly showing that these two CP-violating phenomena can be sourced by a common CP-phase. As an illustration, we work in the Two-Higgs-Doublet model. Because the relevant CP-phase is flavor off-diagonal, this mechanism is less severely constrained by null results of electric dipole moment searches than other scenarios. We show how measurements of flavor observables by the D0, CDF, and LHCb collaborations test this scenario.Comment: 4 pages, 1 figure, 1 tabl

Target localization in wireless sensor networks for industrial control with selected sensors

This paper presents a novel energy-based target localization method in wireless sensor networks with selected sensors. In this method, sensors use Turbo Product Code (TPC) to transmit decisions to the fusion center. TPC can reduce bit error probability if communication channel errors exist. Moreover, in this method, thresholds for the energy-based target localization are designed using a heuristic method. This design method to find thresholds is suitable for uniformly distributed sensors and normally distributed targets. Furthermore, to save sensor energy, a sensor selection method is also presented. Simulation results showed that if sensors used TPC instead of Hamming code to transmit decisions to the fusion center, localization performance could be improved. Furthermore, the sensor selection method used can substantially reduce energy consumption for our target localization method. At the same time, this target localization method with selected sensors also provides satisfactory localization performance

Effect of miR-146a/bFGF/PEG-PEI Nanoparticles on Inflammation Response and Tissue Regeneration of Human Dental Pulp Cells

published_or_final_versio

Palmitoylation at Cys 1145 in the Carboxyl Terminus of Human Type 6 Adenylyl Cyclase is Not Required for Targeting to Lipid Rafts and Caveolae

Palmitoylation is important for targeting certain membrane-associated and integral membrane proteins to lipid rafts and caveolae. Previous data have shown that adenylyl cyclase type 6 (AC6) is enriched in lipid rafts or caveolae while other isoforms of AC, such as AC2 and AC4, are excluded from these domains. We hypothesized that palmitoylation on a cysteine residue in the carboxyl terminus (C-terminus) of AC6 or other elements encoded in this region are required for AC6 expression in lipid rafts and caveolae. Thus, we expressed in Cos-7 cells epitope-tagged full length human AC6 and three different C-terminally truncated AC6 proteins, one (AC6 1-1148) retaining Cys 1145, a putative palmitoylation site, and two others (AC6 1-1144 and AC6 1-1127) lacking this residue. We used several approaches for assessing the subcellular localization of these expressed proteins: non-detergent biochemical isolation of lipid rafts and immunoblotting, immunoprecipitation of caveolin-1, Triton-X-100 insolubility, and immunoisolation of caveolae followed by adenylyl cyclase activity assays. We found that AC6 1-1144, AC6 1-1127 and AC6 1–1148 truncation proteins were each localized similarly to full-length AC6. We conclude that neither the putative palmitoylation site Cys 1145, nor other elements in the distal portion of the carboxyl terminus of AC6, are important for targeting of this effector enzyme to lipid rafts and caveolae

Abelian and Non-Abelian Quantum Geometric Tensor

We propose a generalized quantum geometric tenor to understand topological quantum phase transitions, which can be defined on the parameter space with the adiabatic evolution of a quantum many-body system. The generalized quantum geometric tenor contains two different local measurements, the non-Abelian Riemannian metric and the non-Abelian Berry curvature, which are recognized as two natural geometric characterizations for the change of the ground-state properties when the parameter of the Hamiltonian varies. Our results show the symmetry-breaking and topological quantum phase transitions can be understood as the singular behavior of the local and topological properties of the quantum geometric tenor in the thermodynamic limit.Comment: 5 pages, 2 figure

Microheated substrates for patterning cells and controlling development

Here, we seek to control cellular development by devising a means through which cells can be subjected to a microheated environment in standard culture conditions. Numerous techniques have been devised for controlling cellular function and development via manipulation of surface environmental cues at the micro- and nanoscale. It is well understood that temperature plays a significant role in the rate of cellular activities, migratory behavior (thermotaxis), and in some cases, protein expression. Yet, the effects and possible utilization of micrometer-scale temperature fields in cell cultures have not been explored. Toward this end, two types of thermally isolated microheated substrates were designed and fabricated, one with standard backside etching beneath a dielectric film and another with a combination of surface and bulk micromachining and backside etching. The substrates were characterized with infrared microscopy, finite element modeling, scanning electron microscopy, stylus profilometry, and electrothermal calibrations. Neuron culture studies were conducted on these substrates to 1) examine the feasibility of using a microheated environment to achieve patterned cell growth and 2) selectively accelerate neural development on regions less than 100$mu m$wide. Results show that attached neurons, grown on microheated regions set at 37$~^circ C$, extended processes substantially faster than those incubated at 25$~^circ C$on the same substrate. Further, unattached neurons were positioned precisely along the length of the heater filament (operating at 45$~^circ C$) using free convection currents. These preliminary findings indicate that microheated substrates may be used to direct cellular development spatially in a practical manner.$hfillhbox[1414]