272 research outputs found

    Control of absorption of monolayer MoS2_{2} thin-film transistor in one-dimensional defective photonic crystal

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    The light absorption and transmission of monolayer MoS2_{2} in a one-dimensional defective photonic crystal (d-1DPC) is theoretically investigated. The study shows that the strong interference effect decreases photon density in particular areas of the microcavity. The d-1DPC can reduce light absorption of monolayer MoS2_{2} and enhance light transmission. The impact of monolayer MoS2_{2} light absorption on the localization effect of photon is investigated when monolayer MoS2_{2} and the organic light-emitting diode are located in the same microcavity. However, monolayer MoS2_{2} does not reduce the localization effect of light by regulating the position of monolayer MoS2_{2} in the microcavity.Comment: 5pages,5figure

    (4S,5S)-2-(2-Thien­yl)-1,3-dioxolane-4,5-dicarboxamide

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    In the title compound, C9H10N2O4S, which is an important inter­mediate for the preparation of anti­tumor platinum drugs, the dioxolane ring adopts an envelope conformation with the C atom bonded to the thienyl ring at the flap position. Intra­molecular N—H⋯O and C—H⋯O hydrogen bonds result in the formation of two five-membered rings having envelope conformations. In the crystal structure, inter­molecular N—H⋯O and C—H⋯O hydrogen bonds link the mol­ecules into a three-dimensional network

    Ethyl 1-(6-chloro-3-pyridylmeth­yl)-5-methyl-1H-1,2,3-triazole-4-carboxyl­ate

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    In the title compound, C12H13ClN4O2, the triazole ring carries methyl and ethoxy­carbonyl groups, and is bound via a methyl­ene bridge to a chloro­pyridine unit. There is evidence for significant electron delocalization in the triazolyl system. Intra­molecular C—H⋯O and inter­molecular C—H⋯N hydrogen bonds stabilize the structure

    Synthesis, Characterization and Antitumor Activity of a Series of Polypyridyl Complexes

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    A series of polypyridyl complexes have been synthesized. All polypyridyl complexes and some of the soluble ligands have been assayed for antitumor activity in vitro against the HL-60 (the human leucocytoma) cells, BEL-7402 (the human liver carcinoma) cells, KB (the human nasopharyngeal carcinoma) cells and HELA (the human adenocarcinoma of cervix) cells. The results indicate that several complexes have relative activity against different cell lines. Especially, the complexes [Co(bpy)2(pip)]3+, [Co(phen)2(pip)]3+, [Ru(bpy)2(pztp)]2+ and [Ru(pztp)2(bpy)]2+ show relative high activity against four tumor cell lines. Moreover, they are slightly more effective than cisplatin. At the concentration of 100 μg/mL, the complexes show inhibitory rate of 72∼86% for the cancer cells and have no toxicity for MDCK and Vero cells. It is indicated that these complexes can inhibit cancer cells selectively

    Regulation of the Nrf2/HO-1 axis by mesenchymal stem cells-derived extracellular vesicles: implications for disease treatment

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    This comprehensive review inspects the therapeutic potential of mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) across multiple organ systems. Examining their impact on the integumentary, respiratory, cardiovascular, urinary, and skeletal systems, the study highlights the versatility of MSC-EVs in addressing diverse medical conditions. Key pathways, such as Nrf2/HO-1, consistently emerge as central mediators of their antioxidative and anti-inflammatory effects. From expediting diabetic wound healing to mitigating oxidative stress-induced skin injuries, alleviating acute lung injuries, and even offering solutions for conditions like myocardial infarction and renal ischemia-reperfusion injury, MSC-EVs demonstrate promising therapeutic efficacy. Their adaptability to different administration routes and identifying specific factors opens avenues for innovative regenerative strategies. This review positions MSC-EVs as promising candidates for future clinical applications, providing a comprehensive overview of their potential impact on regenerative medicine

    (4S,5S)-2-(2-Fluoro­phen­yl)-1,3-dioxolane-4,5-dicarboxamide

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    In the mol­ecule of the title compound, C11H11FN2O4, the five-membered ring adopts an envelope conformation. An intra­molecular N—H⋯F hydrogen bond occurs. In the crystal structure, inter­molecular N—H⋯O hydrogen bonds link the mol­ecules
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