272 research outputs found
Control of absorption of monolayer MoS thin-film transistor in one-dimensional defective photonic crystal
The light absorption and transmission of monolayer MoS in a
one-dimensional defective photonic crystal (d-1DPC) is theoretically
investigated. The study shows that the strong interference effect decreases
photon density in particular areas of the microcavity. The d-1DPC can reduce
light absorption of monolayer MoS and enhance light transmission. The
impact of monolayer MoS light absorption on the localization effect of
photon is investigated when monolayer MoS and the organic light-emitting
diode are located in the same microcavity. However, monolayer MoS does
not reduce the localization effect of light by regulating the position of
monolayer MoS in the microcavity.Comment: 5pages,5figure
(4S,5S)-2-(2-Thienyl)-1,3-dioxolane-4,5-dicarboxamide
In the title compound, C9H10N2O4S, which is an important intermediate for the preparation of antitumor platinum drugs, the dioxolane ring adopts an envelope conformation with the C atom bonded to the thienyl ring at the flap position. Intramolecular N—H⋯O and C—H⋯O hydrogen bonds result in the formation of two five-membered rings having envelope conformations. In the crystal structure, intermolecular N—H⋯O and C—H⋯O hydrogen bonds link the molecules into a three-dimensional network
Ethyl 1-(6-chloro-3-pyridylmethyl)-5-methyl-1H-1,2,3-triazole-4-carboxylate
In the title compound, C12H13ClN4O2, the triazole ring carries methyl and ethoxycarbonyl groups, and is bound via a methylene bridge to a chloropyridine unit. There is evidence for significant electron delocalization in the triazolyl system. Intramolecular C—H⋯O and intermolecular C—H⋯N hydrogen bonds stabilize the structure
Synthesis, Characterization and Antitumor Activity of a Series of Polypyridyl Complexes
A series of polypyridyl complexes have been synthesized. All polypyridyl complexes and some of the soluble ligands have been assayed for antitumor activity in vitro against the HL-60 (the human leucocytoma) cells, BEL-7402 (the human liver carcinoma) cells, KB (the human nasopharyngeal carcinoma) cells and HELA (the human adenocarcinoma of cervix) cells. The results indicate that several complexes have relative activity against different cell lines. Especially, the complexes [Co(bpy)2(pip)]3+, [Co(phen)2(pip)]3+, [Ru(bpy)2(pztp)]2+ and [Ru(pztp)2(bpy)]2+ show relative high activity against four tumor cell lines. Moreover, they are slightly more effective than cisplatin. At the concentration of 100 μg/mL, the complexes show inhibitory rate of 72∼86% for the cancer cells and have no toxicity for MDCK and Vero cells. It is indicated that these complexes can inhibit cancer cells selectively
Regulation of the Nrf2/HO-1 axis by mesenchymal stem cells-derived extracellular vesicles: implications for disease treatment
This comprehensive review inspects the therapeutic potential of mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) across multiple organ systems. Examining their impact on the integumentary, respiratory, cardiovascular, urinary, and skeletal systems, the study highlights the versatility of MSC-EVs in addressing diverse medical conditions. Key pathways, such as Nrf2/HO-1, consistently emerge as central mediators of their antioxidative and anti-inflammatory effects. From expediting diabetic wound healing to mitigating oxidative stress-induced skin injuries, alleviating acute lung injuries, and even offering solutions for conditions like myocardial infarction and renal ischemia-reperfusion injury, MSC-EVs demonstrate promising therapeutic efficacy. Their adaptability to different administration routes and identifying specific factors opens avenues for innovative regenerative strategies. This review positions MSC-EVs as promising candidates for future clinical applications, providing a comprehensive overview of their potential impact on regenerative medicine
(4S,5S)-2-(2-Fluorophenyl)-1,3-dioxolane-4,5-dicarboxamide
In the molecule of the title compound, C11H11FN2O4, the five-membered ring adopts an envelope conformation. An intramolecular N—H⋯F hydrogen bond occurs. In the crystal structure, intermolecular N—H⋯O hydrogen bonds link the molecules
- …