Hepatitis following famotidine: a case report

H2 receptor antagonists can rarely cause idiosyncratic drug reactions leading to acute hepatitis. Famotidine, however, is considered a relatively safe drug with regards to hepatotoxicity. We report a case of a 47 year old male with a history of hepatitis C who developed acute hepatitis on the third day of hospitalization with a dramatic rise in his liver enzymes from normal values at the time of admission. The acute rise in liver enzymes made us consider an adverse drug reaction and famotidine was discontinued. Subsequently his liver enzymes came back to normal in seven days. Thus, physicians should consider famotidine induced hepatitis as a possible etiology of acute liver dysfunction

Association of Prenatal and Childhood Blood Lead Concentrations with Criminal Arrests in Early Adulthood

Kim Dietrich and colleagues find an association between developmental exposure to lead and adult criminal behavior

Challenges for Australia's Bio/Nanopharma Policies: trade deals, public goods and reference pricing in sustainable industrial renewal

Industrial renewal in the bio/nanopharma sector is important for the long term strength of the Australian economy and for the health of its citizens. A variety of factors, however, may have caused inadequate attention to focus on systematically promoting domestic generic and small biotechnology manufacturers in Australian health policy

Pharmacotherapeutic disparities: Racial, ethnic, and sex variations in medication treatment

Abstract available at publisher's web site

Using a longitudinal case-based approach to teach population health and disease prevention

Background and purpose: Both colleges of pharmacy in one state separately required a two-credit public and population health course. These courses had been exclusively conducted in a traditional lecture-based format, with little active learning components. Our goal was to redesign and align these required courses across the two colleges of pharmacy using a longitudinal, case-based, active-learning curriculum. Educational activity and setting: Two interprofessional faculty from each university met bi-weekly via videoconference or telephone to: (1) develop an integrated, longitudinal, case-based curriculum with lecture/didactic/case-based materials; and (2) identify and implement an evaluation plan. This course curriculum applied problem-based learning and team-based learning approaches to the Clinical Prevention & Population Health Curricular Framework developed by the Healthy People Curriculum Task Force. Findings: Course evaluations were used to analyze curricular outcomes. Improvement in course evaluation scores and student survey results remained consistent over three years. Students' written comments have also remained overwhelmingly positive over the three-year implementation period. Summary: An interprofessionally developed, longitudinal, case-based curriculum for teaching disease prevention and population health using a social determinants of health approach was determined to be an improved teaching methodology over previous iterations. Although there were challenges in implementing the curriculum across two separate institutions, the overwhelming result was perceived to be positive for both schools, faculty members, and students.12 month embargo; available online 28 April 2020This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

Health Sciences Interprofessional Collaborative: A Perspective on Migration, COVID-19, and the Impact on Indigenous Communities

At the United States-Mexico border, the impacts of immigration policy are dynamic with political, humanitarian, and health outcomes. This article highlights the experiences at the Casa Alitas migrant shelter in Tucson, Arizona. Casa Alitas aims to meet the needs of the im/migrants it serves, including the unique needs of indigenous asylum-seekers from Central America. We highlight the importance of community-based humanitarian response to support asylum-seekers in a way that acknowledges our shared humanity and implements specific approaches (e.g., language justice and trauma informed care). The effort at Casa Alitas is unique because in addition to other partnerships, Casa Alitas established an interprofessional collaboration between the University of Arizona Health Sciences Colleges and the Arizona State University School of Social Work. The interprofessional collaboration encourages mutual education amongst our professions and the use of our extended networks to meet the needs of im/migrants and asylum seekers in our community and the United States. We recommend the development of best practices in asylum health care, the importance of creating border-wide networks to build on local resources, and highlight the importance of exposing future health practitioners to trauma informed and culturally and linguistically appropriate care. © Copyright © 2021 Landau, Sanchez, Kiser, De Zapien, Hall-Lipsy, Pina Lopez, Ingram and Ahumada.Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

Community health worker perspectives of an academic community medication therapy management collaboration

Objective: To qualitatively assess community health workers' (CHWs') perceptions of the challenges and benefits associated with participating in a collaborative, interprofessional medication therapy management (MTM) program for rural, underserved, predominantly Latinx, patients with diabetes and hypertension. Methods: Nine CHWs participated in a 1-hour, semistructured focus group that explored their experiences while assisting in the delivery of MTM services through an academic community partnership between an MTM provider and participating rural clinics. Audio recordings of the focus group were transcribed and thematically analyzed by 2 independent reviewers. Results: All program-involved CHWs participated in the focus group. Qualitative analysis identified 2 overarching themes: (1) opportunities and (2) challenges. Opportunities were further subcategorized as benefits to (1) CHWs, (2) patients, or (3) academic community MTM research. The CHWs perceived that they served as a liaison among the medical provider (prescriber), patient, and MTM pharmacist. Benefits to the patients focused on the integration of CHWs as essential to patient recruitment, especially for those who were reluctant to participate or receive a phone call from a stranger. The major challenges identified were (1) interruptions in workflow and (2) communication between CHWs and the health care practitioners (physicians, nurse practitioners, pharmacists). Specifically, the CHWs universally agreed that they needed more time after receiving patient report, scheduling a visit with the patient, and communicating with the patient's health care provider to better understand the individual's circumstances and needs. Conclusion: This study identified perceived opportunities and challenges faced by CHWs and chronically ill, rural Latinx patients in the acceptance of MTM program. These findings may be useful for all interprofessional health care team members to better understand and appreciate the role of CHWs, while simultaneously enhancing and improving respective medication adherence efforts, and to improve collaborative, academic community programs in the future. (C) 2020 American Pharmacists Association (R). Published by Elsevier Inc. All rights reserved.12 month embargo; published 6 January 2020This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

An Academic-Community Collaboration to Deliver Medication Therapy Management (MTM) Services to Patients Living in Rural Counties of a Southwestern State in the United States

Background: Patients living in rural communities often experience pronounced health disparities, have a higher prevalence of diabetes and hypertension, and poorer access to care compared to urban areas. To address these unmet healthcare service needs, an established, academic-based MTM provider created a novel, collaborative program to provide comprehensive, telephonic services to patients living in rural Arizona counties. Objective: This study assessed the program effectiveness and described differences in health process and outcome measures (e.g., clinical outcomes, gaps in care for prescribed medications, medication-related problems) between individuals residing in different rural-urban commuting area (RUCA) groups (urban, micropolitan, and small town) in rural Arizona counties. Methods: Subjects eligible for inclusion were 18 years or older with diabetes and/or hypertension, living in rural Arizona counties. Data were collected on: demographic characteristics, medical conditions, clinical values, gaps in care, medication-related problems (MRPs), and health promotion guidance. Subjects were analyzed using 3 intra-county RUCA levels (i.e., urban, micropolitan, and small town). Results: A total of 384 patients were included from: urban (36.7%), micropolitan (19.3%) and small town (44.0%) areas. Positive trends were observed for clinical values, gaps in care, and MRPs between initial and follow-up consultations. Urban dwellers had significantly lower average SBP values at follow-up than those from small towns (p < 0.05). A total of 192 MRPs were identified; 75.0% were resolved immediately or referred to providers and 16.7% were accepted by prescribers. Conclusion: This academic-community partnership highlights the benefits of innovative collaborative programs, such as this, for individuals living in underserved, rural areas. © The Author(s) 2021.Centers for Disease Control and PreventionThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]