Interpolated Perturbation-Based Decomposition as a Method for EEG Source Localization

In this thesis, the perturbation-based decomposition technique developed by Szlavik [1] was used in an attempt to solve the inverse problem in EEG source localization. A set of dipole locations were forward modeled using a 4-layer sphere model of the head at uniformly distributed lead locations to form the vector basis necessary for the method. Both a two-dimensional and a pseudo-three-dimensional versions of the model were assessed with the two-dimensional model yielding decompositions with minimal error and the pseudo-three-dimensional version having unacceptable levels of error. The utility of interpolation as a method to reduce the number of data points to become overdefined was assessed as well. The approach was effective as long as the number of component functions did not exceed the number of data points and stayed relatively small (less than 77 component functions). This application of the method to a spatially variate system indicates its potential for other systems and with some tweaking to the least squares algorithm used, could be applied to multivariate systems

A building strategy for development towns in Israel: a synthesis of industrialization and user self-help.

Massachusetts Institute of Technology. Dept. of Architecture. Thesis. 1974. M.Arch.MICROFICHE COPY ALSO AVAILABLE IN ROTCH LIBRARY.Bibliography: leaves [37-38].M.Arch

Surgical perspectives in peptic ulcer disease and gastritis

For much of the twentieth century, surgery was frequently the solution for peptic ulcer disease. Our understanding of the pathophysiology of ulcers paralleled the development of potent pharmaceutical therapy. As the surgical world developed parietal cell vagotomy which would minimize the complications of surgery, patients failing medical therapy became rare. Emergent surgery for complicated peptic ulcers has not declined however. The development of proton pump inhibitors and the full understanding of the impact of H pylori has led to a trend towards minimalism in surgical therapy for complicated peptic ulcer disease. In addition to the changes in patient care, these developments have had an impact on the training of surgeons. This article outlines these trends and developments

Allogeneic Hematopoietic Cell Transplantation for Older Adults with Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a disease that affects adults aged 65 years and above, and survival in this population is poor. Allogeneic hematopoietic cell transplantation (allo-HCT) is a potentially curative therapy for these patients but is underutilized due to frequent comorbidities and perceived higher risk of treatment-related mortality and non-relapse mortality. Increasing data supports the utility of allo-HCT in fit older patients after intensive chemotherapy resulting in improvement of outcomes. With the development of reduced intensity and non-myeloablative conditioning regimens that are associated with lower rates of treatment-related toxicity and mortality, this has allowed more older patients with AML to receive allo-HCT. In this review, we provide some guidance on appropriate selection of older patients as transplant candidates, benefits and risks associated with allo-HCT, conditioning regimen choice, and stem cell transplant sources as they relate to the conduct of stem cell transplantation in older patients

Rochester Regional Health Geriatric Fracture Symposium, 2022, Video 1 of 2

RRH Geriatric Fracture Symposium, October 8, 2022. Presentations in Video 1: Geriatric Fracture Program, Stephen L. Kates, MD, James and Frances McGlothlin Professor and Chair of Orthopaedic Surgery, Virginia Commonwealth University Medical Optimization and Risk Stratification, Anil V. Job, MD, FHM An Algorithm Approach to Hip Fracture Surgery, Stephen L. Kates, MD, James and Frances McGlothlin Professor and Chair of Orthopaedic Surgery, Virginia Commonwealth University Periprosthetic Femur Fractures: Advances in Surgical Management, Jason Lipof, MD Care and Maintenance of the Hospitalized Brain: Prevention, Recognition, Diagnosis, Management and Treatment of Hospital Acquired Cognitive Impairment, Steven A. Rich, MD, Director, Geriatric Consultative Servic

Slc30A8 Nonsynonymous Variant Is Associated With Recovery Following Exercise And Skeletal Muscle Size And Strength

Genome-wide association studies have identified thousands of variants that are associated with numerous phenotypes. One such variant, rs13266634, a nonsynonymous single nucleotide polymorphism in the solute carrier family 30 (zinc transporter) member eight gene, is associated with a 53% increase in the risk of developing type 2 diabetes (T2D). We hypothesized that individuals with the protective allele against T2D would show a positive response to short-term and long-term resistance exercise. Two cohorts of young adults-the Eccentric Muscle Damage (EMD; n = 156) cohort and the Functional Single Nucleotide Polymorphisms Associated with Muscle Size and Strength Study (FAMuSS; n = 874)-were tested for association of the rs13266634 variant with measures of skeletal muscle response to resistance exercise. Our results were sexually dimorphic in both cohorts. Men in the EMD study with two copies of the protective allele showed less post-exercise bout strength loss, less soreness, and lower creatine kinase values. In addition, men in the FAMuSS, homozygous for the protective allele, showed higher pre-exercise strength and larger arm skeletal muscle volume, but did not show a significant difference in skeletal muscle hypertrophy or strength with resistance training. © 2014 by the American Diabetes Association

Efficacy of transarterial embolization as definitive treatment in lower gastrointestinal bleeding

10.1111/j.1463-1318.2008.01536.xColorectal Disease11153-5