Etomidate Should be Used Carefully for Emergent Endotracheal Intubation in Patients with Septic Shock

Etomidate and midazolam are the most popular drugs among the induction agents for emergent endotracheal intubation. The purpose of this study was to compare the incidence of adrenal insufficiency and mortality between the septic shock patients who received etomidate (ETM group) and those who received midazolam (MDZ group). Between November 2004 and September 2006, 65 patients were analyzed in this study. The hospital mortality rate was 36% in the ETM group (n=25) and 50% in the MDZ group (n=40), which was not statistically significant (p=0.269). The incidence of relative adrenal insufficiency was significantly higher in the ETM group than in the MDZ group (84% and 48%, respectively; p=0.003). On multivariate analysis, the use of etomidate was the only significant factor affecting the incidence of relative adrenal insufficiency (odds radio, 5.59; 95% confidence interval, 1.61-19.4). In conclusion, we think that physicians who treat patients with septic shock should be aware that etomidate can cause adrenal insufficiency, and should start corticosteroids if etomidate is administered

Movie Mensch: An Exploration of Spielberg’s Universalist Jewish-American Sensibility

Throughout his career, Steven Spielberg has depicted America as a haven for minorities with considerable onscreen patriotic sentiments, while garnering criticism for having often (and conveniently) rewritten history, omitted facts or changed them altogether (Pryce 1997; Mitchell 1998; Gates 1987). In this regard, the story of European-Jewish immigration and successful assimilation woven into the very fabric of the American Dream has been central to Spielberg’s oeuvre, together with the expres..

Buch der Freude.

Book-plate: Dr. Egon Bergson.Poems.Mode of access: Internet

Vasopresseurs et inotropes dans le choc septique (revue systématique et méta-analyse de la littérature)

PARIS7-Xavier Bichat (751182101) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF