Primary tuberculous abscess of chest wall in a young immunocompetent female

Chest wall tuberculosis (TB) is rarely reported in immunocompetent individuals and is usually a part of disseminated disease. A tuberculous abscess may mimic pyogenic abscess and unless strongly suspected, tuberculous etiology may be missed due to paucibacillary nature of extrapulmonary lesions. Molecular diagnostic tests can prove useful by providing a rapid and accurate diagnosis in such cases. We present here a case of chest wall tuberculous abscess without any evidence of immunosuppression or previous history of TB

A Rare Case of Primary Anterior Chest Wall Abscess due to Salmonella Typhi in an Immunocompetent Male

A case of suspicious anterior chest wall mass due to Salmonella enterica serotype Typhi in a middle aged, non- diabetic male is being described. The infection was successfully treated with timely institution of antibiotic treatment. This case highlights the fact that a focal Salmonella infection involving the anteriorchest wall should be considered as a differential diagnosis and not treated as tuberculosis empirically. Submission of specimens for microbiological analysis should be performed for an accurate diagnosis and management

Pseudomonas mendocina Wound Infection in a Farmer: A Rare Case

The members of the family Pseudomonadaceae have been reorganised under various groups, each with several species and are known as opportunistic pathogens. Pseudomonas mendocina (P.mendocina) formerly known as CDC group Vb-2, belongs to stutzeri group (group II) and was first discovered in 1970 in Mendoza. The present case report is about an overwhelming leg ulcer in an asthmatic and diabetic 53-year-old, Indian farmer following a fall due to a multi-drug resistant strain of P.mendocina without any systemic spread due to timely intervention. Authors emphasise that P. mendocina may be an important emerging pseudomonad or alternatively an under-diagnosed pathogen in immunocompromised patients exposed to soil. The multidrug resistant nature of this organism is alarming and it may become a threat to people with weakened immune systems

Characterization and antimicrobial susceptibility of coagulase-negative staphylococci isolated from clinical samples

PURPOSE: This study has been done to speciate coagulase-negative staphylococci (CoNS) and also study their antibiotic susceptibility pattern isolated from clinical samples. MATERIALS AND METHODS: A total of 120 consecutive CoNS were isolated from various clinical samples such as blood, pus, wound swab, drain fluid, tracheal aspirate, peritoneal fluid, and pleural fluid over a period of 6 months. CoNS were identified by characteristic growth on media such as Blood agar and MacConkey agar. Speciation and identification were done by a range of biochemical testing such as PYR broth hydrolysis, novobiocin resistance, polymyxin B sensitivity, and then by matrix-assisted laser desorption ionization-time of flight. Antibiotic susceptibility of the isolates was done by Kirby-Bauer disk diffusion method as per CLSI 2017 guidelines. RESULTS: Among the 120 isolates, the most common species was Staphylococcus epidermidis (56.67%) followed by Staphylococcus haemolyticus (21.67%), Staphylococcus lugdunensis (11.67%), Staphylococcus caprae (5%), Staphylococcus cohnii (3.33%), and finally Staphylococcus vitulinus (1.67%). Good in vitro susceptibility was noted toward linezolid (100%), vancomycin (100%), teicoplanin (100%), and doxycycline (80.2%). The antibiotics to which resistance was seen were penicillin (96.5%), ciprofloxacin (57.1%), and oxacillin (45.5%). MR CoNS in our study ranged from 50% to 68.67%. CONCLUSION: Antibiotic resistance in CoNS is increasing toward penicillin, ciprofloxacin, and oxacillin as found in our study. The antibiotics such as vancomycin, teicoplanin, linezolid, and doxycycline which showed good in vitro susceptibility, therefore, should be kept as reserve drugs and used judiciously