Coordinating UoS engagement events

This booklet is Coordinating UoS Engagement Events and provides further information and details on ways in which diverse teams across the University can help you to maximise the impact of your public & community engagement activities. Aims of this eBook: • Specifically focuses on how to get started with planning and running an engagement event, with links • Provides guidance and advice on evaluating and documenting your engagement event • Provides information about the training & development and internal funding available • Encourages reflection and self-evaluation throughout the development process • Sign-posts to useful internal and external resources, tools, tips and techniques • Promotes goal setting and development of confidence and capabilit

Getting started with impact

This booklet is Getting Started with Impact and provides further information and details on ways in which to embed real-world impact from the outset of your research projects to ensure maximum benefit to your publics and stakeholders. Aims of this eBook: • Specifically focuses on how to get started with impact, with links to templates • Provides information about the training & development and internal funding available • Encourages reflection and self-evaluation throughout the development process • Sign-posts to useful internal and external resources, tools, tips and techniques • Promotes goal setting and development of confidence and capabilit

Developing widening engagement activities and events

This booklet is Developing Widening Engagement Activities and Events and provides further information and details about the process and a practical guide to delivering events to connect to and communicate your research. Aims of this eBook: • Specifically focuses on designing, developing and delivering public engagement (PE) in person events and activities, with useful links and tools • Used alongside PDR and Development Plans to identify development opportunities • Supports decision making and work in areas of research impact, finding funding for research and in preparation for the REF and KEF processes as well as supporting individual and organisational objectives • Sets out expectations and limitations of the possibilities to help focus time and resource appropriately • Facilitates preparation in advance of key milestones and PE events in the annual calendar • Encourages reflection and self-evaluation throughout the development process • Sign-posts to useful resources, tools, tips and techniques • Promotes goal setting and development of confidence and capabilit

Quick start guide to public & community engagement

This booklet is Getting Started with Public & Community Engagement and provides further information and details about the process of public engagement with research. Aims of this eBook: • Specifically focuses on widening engagement (this is largely focussed on the public engagement of research but also touches upon elements of widening participation and enterprise), with useful links and tools • Provides detailed information about the training and development available • Designed to help plan your attendance and participation in appropriate training • Used alongside PDR and Development Plans to identify development opportunities • Support decision making and work in areas of research impact, finding funding for research and in preparation for the REF and KEF processes as well as supporting individual and organisational objectives • Sets out expectations and limitations of the training to help focus time and resource appropriately • Facilitates preparation in advance of attendance and participation • Encourages reflection and self-evaluation throughout the development process • Sign-posts to useful resources, tools, tips and techniques • Promotes goal setting and development of confidence and capabilit

Working with Government and influencing policy

This booklet is Working with Government and Influencing Policy and provides further information and details on ways in which to engage with and influence policy makers and other key stakeholders to maximise the reach and significance of your research impact. Aims of this eBook: • Specifically focuses on how to get started with policy engagement, with links • Provides information about the training & development and internal funding available • Encourages reflection and self-evaluation throughout the development process • Sign-posts to useful internal and external resources, tools, tips and techniques • Promotes goal setting and development of confidence and capabilit

Mesenchymal stem cells and immunomodulation: current status and future prospects

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Intercultural New Media Studies: The Next Frontier in intercultural Communication

New media (ICT\u27s) are transforming communication across cultures. Despite this revolution in cross cultural contact, communication researchers have largely ignored the impact of new media on intercultural communication. This groundbreaking article defines the parameters of a new field of inquiry called Intercultural New Media Studies (INMS), which explores the intersection between ICT\u27s and intercultural communication. Composed of two research areas—(1) new media and intercultural communication theory and (2) culture and new media—INMS investigates new digital theories of intercultural contact as well as refines and expands twentieth-century intercultural communication theories, examining their salience in a digital world. INMS promises to increase our understanding of intercultural communication in a new media age and is the next frontier in intercultural communication

A novel long non-coding natural antisense RNA is a negative regulator of Nos1 gene expression

Long non-coding natural antisense transcripts (NATs) are widespread in eukaryotic species. Although recent studies indicate that long NATs are engaged in the regulation of gene expression, the precise functional roles of the vast majority of them are unknown. Here we report that a long NAT (Mm-antiNos1 RNA) complementary to mRNA encoding the neuronal isoform of nitric oxide synthase (Nos1) is expressed in the mouse brain and is transcribed from the non-template strand of the Nos1 locus. Nos1 produces nitric oxide (NO), a major signaling molecule in the CNS implicated in many important functions including neuronal differentiation and memory formation. We show that the newly discovered NAT negatively regulates Nos1 gene expression. Moreover, our quantitative studies of the temporal expression profiles of Mm-antiNos1 RNA in the mouse brain during embryonic development and postnatal life indicate that it may be involved in the regulation of NO-dependent neurogenesis

Identification of the genomic mutation in Epha4rb-2J/rb-2J mice

The EphA4 receptor tyrosine kinase is involved in numerous cell-signalling activities during embryonic development. EphA4 has the ability to bind to both types of ephrin ligands, the ephrinAs and ephrinBs. The C57BL/6J-Epha4rb-2J/GrsrJ strain, denoted Epha4rb-2J/rb-2J, is a spontaneous mouse mutant that arose at The Jackson Laboratory. These mutants exhibited a synchronous hind limb locomotion defect or “hopping gait” phenotype, which is also characteristic of EphA4 null mice. Genetic complementation experiments suggested that Epha4rb-2J corresponds to an allele of EphA4, but details of the genomic defect in this mouse mutant are currently unavailable. We found a single base-pair deletion in exon 9 resulting in a frame shift mutation that subsequently resulted in a premature stop codon. Analysis of the predicted structure of the truncated protein suggests that both the kinase and sterile α motif (SAM) domains are absent. Definitive determination of genotype is needed for experimental studies of mice carrying the Epha4rb-2J allele, and we have also developed a method to ease detection of the mutation through RFLP. Eph-ephrin family members are reportedly expressed as numerous isoforms. Hence, delineation of the specific mutation in EphA4 in this strain is important for further functional studies, such as protein–protein interactions, immunostaining and gene compensatory studies, investigating the mechanism underlying the effects of altered function of Eph family of receptor tyrosine kinases on phenotype