An Alternative to Temporary Staffing: Considerations for Workforce Practitioners

The temporary staffing industry has become a fixture of the US economy in recent decades, and workforce practitioners are increasingly noting the prevalence of temporary jobs in the low-skilled labor market. To ensure that these jobs are a stepping stone for job seekers -- and to tap into additional sources of revenue -- a growing number of social service organizations have launched their own staffing businesses, known as alternative staffing organizations (ASOs)

An Alternative to Temporary Staffing: Considerations for Workforce Practitioners

As the national economy inches toward recovery, risk-averse employers are increasingly turning to temporary workers to fill their hiring gaps. In fact, the temporary staffing industry has been a fixture of the US economy for decades. But the industry added a striking 557,000 jobs from June 2009 to November 2011 — more than half of the jobs created during that period. Growth is likely to continue: A 2011 McKinsey survey of 2,000 firms of differing sizes and across various sectors found that more than a third foresaw their companies increasing their use of temporary workers over the next five years. The bulk of these temporary workers are employed by for-profit temporary staffing firms that recruit and screen candidates for assignments, as well as handle payroll and a few supervisory duties. These firms supply workers for a sizable share of the low- and semi-skilled, entry-level job openings across many diverse sectors, including blue-collar manufacturing, office/clerical, healthcare and IT. Workforce development practitioners — who aim to help those with barriers to employment get and keep jobs — have been struggling to make sense of what this growth in the temporary sector means for their clients. While research examining the effects of temporary jobs on subsequent employment and long-term earnings is mixed, such jobs are likely here to stay. It seems clear that temporary staffing firms will play an increasingly large role in filling the type of job openings that workforce programs often target for their participants. How can program staff navigate this labor market phenomenon? This brief describes the work of “alternative staffing organizations” (ASOs), which seek to mitigate some of the more troubling shortcomings of the temporary employment industry (see “Opportunities, Risks and Dangers of Temporary Jobs” on the next page) with the goal of improving the employment prospects of the most vulnerable job seekers

2006 A Spotlight on San Diego\u27s Third Sector

In conjunction with the University of San Francisco\u27s Institute for Nonprofit Organization Management, the Center produced a report focused on the contributions of the San Diego nonprofit sector to the local economy. This report\u27s intent is to create an understanding of the nonprofit sector, measure its capacity & economic contributions, and chart its future. This project was presented November 13, 2006.https://digital.sandiego.edu/npi-stateofnp/1011/thumbnail.jp

A Spotlight on San Diego's Third Sector

In conjunction with the University of San Francisco's Institute for Nonprofit Organization Management, the Center produced a report focused on the contributions of the San Diego nonprofit sector to the local economy. This report's intent is to create an understanding of the nonprofit sector, measure its capacity and economic contributions, and chart its future. This project was presented November 13, 2006

Polyfluoroalkyl Compounds in Texas Children from Birth through 12 Years of Age

Background: For > 50 years, polyfluoroalkyl compounds (PFCs) have been used worldwide, mainly as surfactants and emulsifiers, and human exposure to some PFCs is widespread

miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1

Diabetic kidney disease (DKD) is a major complication of diabetes. Expression of members of the microRNA (miRNA) miR-379 cluster is increased in DKD. miR-379, the most upstream 5′-miRNA in the cluster, functions in endoplasmic reticulum (ER) stress by targeting EDEM3. However, the in vivo functions of miR-379 remain unclear. We created miR-379 knockout (KO) mice using CRISPR-Cas9 nickase and dual guide RNA technique and characterized their phenotype in diabetes. We screened for miR-379 targets in renal mesangial cells from WT vs. miR-379KO mice using AGO2-immunopreciptation and CLASH (cross-linking, ligation, sequencing hybrids) and identified the redox protein thioredoxin and mitochondrial fission-1 protein. miR-379KO mice were protected from features of DKD as well as body weight loss associated with mitochondrial dysfunction, ER- and oxidative stress. These results reveal a role for miR-379 in DKD and metabolic processes via reducing adaptive mitophagy. Strategies targeting miR-379 could offer therapeutic options for DKD

Event detection using roles and relationships of entities

A method, system, and computer program product for event detection using roles and relationships of entities are provided in the illustrative embodiments. A training event and a set of entities participating in the training event are identified in a training data. For a first entity in the set of entities, a first role occupied by the entity in the event is determined. A behavior attribute is assigned to the first role. A relationship of the first role with a second role corresponding to a second entity in the set of entities is determined. An event rule is constructed to detect an event corresponding to the training event in new data and comprising a plurality of roles, behavior attributes, and the relationship. The plurality of roles includes the first role and the second role, and the plurality of behavior attributes includes the behavior attribute assigned to the first role.Board of Regents, University of Texas Syste

Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors.

Tumor-associated macrophages (TAM) contribute to all aspects of tumor progression. Use of CSF1R inhibitors to target TAM is therapeutically appealing, but has had very limited anti-tumor effects. Here, we have identified the mechanism that limited the effect of CSF1R targeted therapy. We demonstrated that carcinoma-associated fibroblasts (CAF) are major sources of chemokines that recruit granulocytes to tumors. CSF1 produced by tumor cells caused HDAC2-mediated downregulation of granulocyte-specific chemokine expression in CAF, which limited migration of these cells to tumors. Treatment with CSF1R inhibitors disrupted this crosstalk and triggered a profound increase in granulocyte recruitment to tumors. Combining CSF1R inhibitor with a CXCR2 antagonist blocked granulocyte infiltration of tumors and showed strong anti-tumor effects

Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia:Recent Progress on the Mechanisms and Interventional Strategies

Unhealthy aging poses a global challenge with profound healthcare and socioeconomic implications. Slowing down the aging process offers a promising approach to reduce the burden of a number of age-related diseases, such as dementia, and promoting healthy longevity in the old population. In response to the challenge of the aging population and with a view to the future, Norway and the United Kingdom are fostering collaborations, supported by a "Money Follows Cooperation agreement" between the 2 nations. The inaugural Norway-UK joint meeting on aging and dementia gathered leading experts on aging and dementia from the 2 nations to share their latest discoveries in related fields. Since aging is an international challenge, and to foster collaborations, we also invited leading scholars from 11 additional countries to join this event. This report provides a summary of the conference, highlighting recent progress on molecular aging mechanisms, genetic risk factors, DNA damage and repair, mitophagy, autophagy, as well as progress on a series of clinical trials (eg, using NAD+ precursors). The meeting facilitated dialogue among policymakers, administrative leaders, researchers, and clinical experts, aiming to promote international research collaborations and to translate findings into clinical applications and interventions to advance healthy aging.</p