MIOEPITELIOMA DE PARTES MOLES DO RETO: RELATO DE CASO

Annotated in handwritten ink: To Genl. Robert Anderson with the compliments of J.E. Hilgard, Assist. U.S. Coast Survey.; Relief shown by hachures.; General map of eastern Virginia showing cities and towns, roads, rivers, and relief by hachures. The map is overprinted in red to indicate railroads and concentric circles centered on Richmond. Circles are at intervals of ten miles.; In his report to the Superintendent of the Coast survey dated November 1, 1862, Nicholson notes that "In addition to the printing of our charts proper, a map representing the seat of war in Virginia was, at the suggestion of the Superintendent, compiled by myself during the past year, and printed in colors, partly as an experiment in that class of work, and partly to meet the popular demand for information on the movements of our armies. This map has met with unexpected success, and has been much called for, and copies quite freely distributed; but, in order to cover the expenses of its getting up and printing, a number of copies have been placed in the hands of our sale agents, the proceeds of which have more than covered expenses; in all, some five thousand five hundred copies have been printed, over twenty-five hundred sold, and nearly three thousand copies gratuitously distributed." (Report of the Superintendent of the Coast Survey, showing the Progress of the Survey during the Year 1862 (Washington: Government Printing Office, 1864). p. 151.).; This is the first of seven issues in the Library of Congress published in 1862. Distinguishing characteristics include the depiction of the "Blairsville Branch" railroad, the "Manassas Gap R.R." extending to Harrisonburg, Virginia, and the "Delaware R.R." on the Eastern Shore extending to Seaford.; Description derived from published bibliography.1:887,04

Variables associated with progression of moderate-to-severe Crohn’s disease

Objective Determine the variables associated with hospitalisations in patients with Crohn’s disease and those associated with surgery, intestinal resection, hospital readmission, need for multiple operations and immunobiological agent use.Design A cross-sectional study was conducted from 2019 to 2021, using two centres for inflammatory bowel diseases in the Brazilian Public Health System.Results This study included 220 patients. Only perianal disease was associated with hospitalisation (31.6% vs 13.0%, p=0.012). Stricturing or penetrating behaviour (35.8% vs 12.6%, p<0.001) and perianal disease (45.9% vs 9.9%, p<0.001) were associated with surgery. Ileal or ileocolonic location (80.0% vs 46.5%, p=0.044) and stricturing or penetrating behaviour (68.0% vs 11.2%, p<0.001) were associated with intestinal resection. Steroids use at first Crohn’s disease occurrence and postoperative complications were associated with hospital readmission and need for multiple operations, respectively. Age below 40 years at diagnosis (81.3% vs 62.0%, p=0.004), upper gastrointestinal tract involvement (21.8% vs 10.3%, p=0.040) and perianal disease (35.9% vs 16.3%, p<0.001) were associated with immunobiological agent use.Conclusion Perianal disease and stricturing or penetrating behaviour were associated with more than one significant outcome. Other variables related to Crohn’s disease progression were age below 40 years at diagnosis, an ileal or ileocolonic disease localisation, an upper gastrointestinal tract involvement, the use of steroids at the first Crohn’s disease occurrence and history of postoperative complications. These findings are similar to those in the countries with a high prevalence of Crohn’s disease