Potential of Core-Collapse Supernova Neutrino Detection at JUNO

JUNO is an underground neutrino observatory under construction in Jiangmen, China. It uses 20kton liquid scintillator as target, which enables it to detect supernova burst neutrinos of a large statistics for the next galactic core-collapse supernova (CCSN) and also pre-supernova neutrinos from the nearby CCSN progenitors. All flavors of supernova burst neutrinos can be detected by JUNO via several interaction channels, including inverse beta decay, elastic scattering on electron and proton, interactions on C12 nuclei, etc. This retains the possibility for JUNO to reconstruct the energy spectra of supernova burst neutrinos of all flavors. The real time monitoring systems based on FPGA and DAQ are under development in JUNO, which allow prompt alert and trigger-less data acquisition of CCSN events. The alert performances of both monitoring systems have been thoroughly studied using simulations. Moreover, once a CCSN is tagged, the system can give fast characterizations, such as directionality and light curve

Detection of the Diffuse Supernova Neutrino Background with JUNO

As an underground multi-purpose neutrino detector with 20 kton liquid scintillator, Jiangmen Underground Neutrino Observatory (JUNO) is competitive with and complementary to the water-Cherenkov detectors on the search for the diffuse supernova neutrino background (DSNB). Typical supernova models predict 2-4 events per year within the optimal observation window in the JUNO detector. The dominant background is from the neutral-current (NC) interaction of atmospheric neutrinos with 12C nuclei, which surpasses the DSNB by more than one order of magnitude. We evaluated the systematic uncertainty of NC background from the spread of a variety of data-driven models and further developed a method to determine NC background within 15\% with {\it{in}} {\it{situ}} measurements after ten years of running. Besides, the NC-like backgrounds can be effectively suppressed by the intrinsic pulse-shape discrimination (PSD) capabilities of liquid scintillators. In this talk, I will present in detail the improvements on NC background uncertainty evaluation, PSD discriminator development, and finally, the potential of DSNB sensitivity in JUNO

Real-time Monitoring for the Next Core-Collapse Supernova in JUNO

Core-collapse supernova (CCSN) is one of the most energetic astrophysical events in the Universe. The early and prompt detection of neutrinos before (pre-SN) and during the SN burst is a unique opportunity to realize the multi-messenger observation of the CCSN events. In this work, we describe the monitoring concept and present the sensitivity of the system to the pre-SN and SN neutrinos at the Jiangmen Underground Neutrino Observatory (JUNO), which is a 20 kton liquid scintillator detector under construction in South China. The real-time monitoring system is designed with both the prompt monitors on the electronic board and online monitors at the data acquisition stage, in order to ensure both the alert speed and alert coverage of progenitor stars. By assuming a false alert rate of 1 per year, this monitoring system can be sensitive to the pre-SN neutrinos up to the distance of about 1.6 (0.9) kpc and SN neutrinos up to about 370 (360) kpc for a progenitor mass of 30$M_{\odot}$ for the case of normal (inverted) mass ordering. The pointing ability of the CCSN is evaluated by using the accumulated event anisotropy of the inverse beta decay interactions from pre-SN or SN neutrinos, which, along with the early alert, can play important roles for the followup multi-messenger observations of the next Galactic or nearby extragalactic CCSN.Comment: 24 pages, 9 figure

Severe pediatric adenoviral pneumonia combined with invasive pulmonary aspergillosis

Abstract Background This study aimed to analyze the clinical characteristics of severe pediatric adenoviral pneumonia combined with invasive pulmonary aspergillosis. Methods We retrospectively analyzed the clinical data of five children clinically diagnosed with severe adenoviral pneumonia combined with invasive pulmonary aspergillosis at Xiamen Children’s Hospital. Results These five children included one boy and four girls, with ages of onset ranging from 8 months and 15 days to 2 years and 2 months. All of them had fever with a mean duration of 11–35 days and cough. Pulmonary imaging was performed, which revealed solid pulmonary opacification in all five children, pleural effusion in two children, and emphysema and multiple small cavity formations in one child. Multiple microbiological tests were performed on the 5 children, and adenovirus was positive in the alveolar lavage fluid for the first time, and aspergillus culture was positive in the second test. On tracheoscopy, the bronchial mucosa was seen to be congested and edematous or pale and eroded; white moss-like material was seen adhering to the tracheal wall or even blocking the airway. The five children were treated with a combination of two or more broad-spectrum antimicrobials, glucocorticoids, and gamma globulins and underwent bronchoscopy. Voriconazole was added in the treatment regimen after the diagnosis of aspergillosis (28–34 days of treatment). Four of the children were discharged in good condition with a mean total length of hospital stay of 17–47 days. The other child leave against medical advice. Follow-up 3–5 months after discharge showed that one child had been cured; two children had developed obliterative bronchiolitis; one child had developed bronchiectasis; and the remaining child who had been discharged spontaneously was not contactable via telephone. Conclusions Immune disorders and antibiotic and steroid treatments for adenovirus infection are high-risk factors for secondary invasive pulmonary aspergillosis in children. Prolonged fever and cough are the main manifestations, but which lack specificity, and bronchoscopic mucosal-specific injury evaluation and alveolar lavage fluid culture are helpful in the diagnosis of aspergillosis. The long-term prognosis of severe pediatric adenoviral pneumonia combined with invasive pulmonary aspergillosis maybe poor

A New Approach to Calculate the Shielding Factor of Magnetic Shields Comprising Nonlinear Ferromagnetic Materials under Arbitrary Disturbances

To enable the realization of ultra-low magnetic fields for scientific and technological research, magnetic shielding is required to create a space with low residual magnetic field and high shielding factors. The shielding factors of magnetic shields are due to nonlinear material properties, the geometry and structure of the shields, and the external magnetic fields. Magnetic shielding is used in environments full of random realistic disturbances, resulting in an arbitrary and random external magnetic field, and in this case, the shielding effect is hard to define simply by the shielding factors. A new method to simulate and predict a dynamic internal space magnetic field wave is proposed based on the Finite Element method (FEM) combined with the Jiles-Atherton (JA) model. By simulating the hysteresis behavior of the magnetic shields and establishing a dynamic model, the new method can simulate dynamic magnetic field changes inside magnetic shields as long as the external disturbances are known. The shielding factors under an AC external field with a sine wave and certain frequencies are calculated to validate the feasibility of the new method. A real-time wave of internal magnetic flux density under an AC triangular wave external field is simulated directly with the new method versus a method that splits the triangular wave into several sine waves by a Fourier transform, divides the shielding factors, and then adds the quotients together. Moreover, real-time internal waves under some arbitrary fields are measured. Experimental internal magnetic flux density waves of a 4-layer magnetically shielded room (MSR) at the Harbin Institute of Technology (HIT) fit the simulated results well, taking experimental errors into account

Combined dilute hydrochloric acid and alkaline wet oxidation pretreatment to improve sugar recovery of corn stover

Two-stage dilute hydrochloric acid (DA)/aqueous ammonia wet oxidation (AWO) pretreatment was used to recover the sugars of corn stover. The morphology characterizations of samples were detected by SEM, BET and SXT. The results showed that DA-AWO process demonstrated a positive effect on sugar recovery compared to AWO-DA. 82.8% of xylan was recovered in the first stage of DA-AWO process at 120 degrees C for 40 min with 1 wt% HCl. The second stage was performed under relative mild reaction conditions (130 degrees C, 12.6 wt% ammonium hydroxide, 3.0 MPa O-2, 40 min), and 86.1% lignin could be removed. 71.5% of glucan was achieved with a low enzyme dosage (3 FPU.g(-1)) in the following enzymatic hydrolysis. DA-AWO pretreatment was effective due to its sufficient hydrolysis of hemicellulose in the first stage and remarkably removal of the lignin in the second stage, resulting in high sugar recovery with a low enzyme dosage

Optimization of a Coil System for Generating Uniform Magnetic Fields inside a Cubic Magnetic Shield

Ultra-low magnetic fields have drawn lots of attention due to their important role in scientific and technological research. The combination of a magnetic shield and an active compensation coil is adopted in most high performance magnetically shielded rooms. Special consideration needs to be taken in the coil design since the magnetic shield significantly affects the uniformity of the magnetic field that is generated by the coil. An analytical model for the magnetic field calculation of the coil inside a cubic magnetic shield is proposed based on the generalized image method, which is validated by finite element analysis. A novel design method of the coil used in a cubic magnetic shield with a large homogeneous volume is proposed. The coil parameters are optimized to obtain a large cubic uniform volume with desired total deviation rate by discretizing the central volume in the coil. In the desired total deviation rate, the normalized usable volume of the new coil increases by 70% when compared with the Merritt coil. A coil system is developed according to the parameters obtained based on this method. The magnetic flux density and practical deviation rate of the coil are measured to validate the accuracy of this model and the feasibility of the design method. The experimental magnetic flux density agrees well with the analytical value. The maximum practical deviation rate of uniform volume of 0.8 × 0.8 × 0.8 m is in good agreement with the theoretical design value, taking into account the experiment errors

Bioactive Sulfur-Containing Sulochrin Dimers and Other Metabolites from an <i>Alternaria</i> sp. Isolate from a Hawaiian Soil Sample

Polluxochrin (<b>1</b>) and dioschrin (<b>2</b>), two new dimers of sulochrin linked by thioether bonds, were purified from an <i>Alternaria</i> sp. isolate obtained from a Hawaiian soil sample. The structures of the two metabolites were established by NMR, mass spectrometry data, and X-ray analysis. Metabolite <b>1</b> was determined to be susceptible to intramolecular cyclization under aqueous conditions, resulting in the generation of <b>2</b> as well as another dimeric compound, castochrin (<b>3</b>). An additional nine new metabolites were also obtained, including four new pyrenochaetic acid derivatives (<b>8</b>–<b>11</b>), one new asterric acid analogue (<b>13</b>), and four new secalonic acid analogues (<b>14</b>–<b>17</b>). Bioassay analysis of these compounds revealed <b>1</b>–<b>3</b> displayed antimicrobial and weak cytotoxic activities