A new time-frequency method to reveal quantum dynamics of atomic hydrogen in intense laser pulses: Synchrosqueezing Transform

This study introduces a new adaptive time-frequency (TF) analysis technique, synchrosqueezing transform (SST), to explore the dynamics of a laser-driven hydrogen atom at an {\it ab initio} level, upon which we have demonstrated its versatility as a new viable venue for further exploring quantum dynamics. For a signal composed of oscillatory components which can be characterized by instantaneous frequency, the SST enables rendering the decomposed signal based on the phase information inherited in the linear TF representation with mathematical support. Compared with the classical type TF methods, the SST clearly depicts several intrinsic quantum dynamical processes such as selection rules, AC Stark effects, and high harmonic generation

A study of the Effects of Information Security Advocacy

This study adopted protection motivation theory, construal-level theory, and regulatory focus theory to build a model to understand the effects of information security advocacy. The purposes are as follows: first, understand the impacts on the threat/coping appraisals that different construal-level of security warning messages have. Second, understand the impacts on the information security compliance intention that threat/coping appraisals have. Lastly, understand the moderating effects of different regulatory foci on the relationship between different construallevel of warning messages and the threat/coping appraisals or between the threat/coping appraisals and the compliance intention. In this study, the experimental method and survey are employed. Eight different scenarios related to mobile phone authority setting are designed to proceed with the experiments. At the beginning of this experiment, the participants will be manipulated to a particular regulatory focus (prevention or promotion), then be assigned to one of eight scenarios randomly

DMC-Net: Generating Discriminative Motion Cues for Fast Compressed Video Action Recognition

Motion has shown to be useful for video understanding, where motion is typically represented by optical flow. However, computing flow from video frames is very time-consuming. Recent works directly leverage the motion vectors and residuals readily available in the compressed video to represent motion at no cost. While this avoids flow computation, it also hurts accuracy since the motion vector is noisy and has substantially reduced resolution, which makes it a less discriminative motion representation. To remedy these issues, we propose a lightweight generator network, which reduces noises in motion vectors and captures fine motion details, achieving a more Discriminative Motion Cue (DMC) representation. Since optical flow is a more accurate motion representation, we train the DMC generator to approximate flow using a reconstruction loss and a generative adversarial loss, jointly with the downstream action classification task. Extensive evaluations on three action recognition benchmarks (HMDB-51, UCF-101, and a subset of Kinetics) confirm the effectiveness of our method. Our full system, consisting of the generator and the classifier, is coined as DMC-Net which obtains high accuracy close to that of using flow and runs two orders of magnitude faster than using optical flow at inference time.Comment: Accepted by CVPR'1

Learning to predict expression efficacy of vectors in recombinant protein production

<p>Abstract</p> <p>Background</p> <p>Recombinant protein production is a useful biotechnology to produce a large quantity of highly soluble proteins. Currently, the most widely used production system is to fuse a target protein into different vectors in <it>Escherichia coli </it>(<it>E. coli</it>). However, the production efficacy of different vectors varies for different target proteins. Trial-and-error is still the common practice to find out the efficacy of a vector for a given target protein. Previous studies are limited in that they assumed that proteins would be over-expressed and focused only on the solubility of expressed proteins. In fact, many pairings of vectors and proteins result in no expression.</p> <p>Results</p> <p>In this study, we applied machine learning to train prediction models to predict whether a pairing of vector-protein will express or not express in <it>E. coli</it>. For expressed cases, the models further predict whether the expressed proteins would be soluble. We collected a set of real cases from the clients of our recombinant protein production core facility, where six different vectors were designed and studied. This set of cases is used in both training and evaluation of our models. We evaluate three different models based on the support vector machines (SVM) and their ensembles. Unlike many previous works, these models consider the sequence of the target protein as well as the sequence of the whole fusion vector as the features. We show that a model that classifies a case into one of the three classes (no expression, inclusion body and soluble) outperforms a model that considers the nested structure of the three classes, while a model that can take advantage of the hierarchical structure of the three classes performs slight worse but comparably to the best model. Meanwhile, compared to previous works, we show that the prediction accuracy of our best method still performs the best. Lastly, we briefly present two methods to use the trained model in the design of the recombinant protein production systems to improve the chance of high soluble protein production.</p> <p>Conclusion</p> <p>In this paper, we show that a machine learning approach to the prediction of the efficacy of a vector for a target protein in a recombinant protein production system is promising and may compliment traditional knowledge-driven study of the efficacy. We will release our program to share with other labs in the public domain when this paper is published.</p