Submandibular Cavernous Hemangiomas with Multiple Phleboliths Masquerading as Sialolithiasis

Vasoformative tumors (almost exclusively hemangiomas) are the most common lesions of the major salivary glands during infancy and early childhood. They are more common in the parotid gland but are particularly rare in the submandibular gland. Changes in blood flow dynamics within hemangiomas result in thrombus formation and phleboliths. Hemangiomas of the salivary glands in adults are histologically unlike those in infants, the former being characteristically of the cavernous variant. Most cavernous hemangiomas require surgery since they do not show a tendency to regress. A case of an adult man with cavernous hemangioma affecting the submandibular salivary gland that clinically simulated sialolithiasis is presented to alert surgeons to the possibility of such a lesion. We describe the clinical course and review the literature

Impact of Lattice Strangeness Asymmetry Data in the CTEQ-TEA Global Analysis

We study the impact of lattice data on the determination of the strangeness asymmetry distribution $s_-(x) \equiv s(x) - {\bar s}(x)$ in the general CTEQ-TEA global analysis of parton distribution functions (PDFs) of the proton. Firstly, we find that allowing a nonvanishing $s_-(x)$, at the initial $Q_0=1.3$~GeV scale, in a global PDF analysis leads to a CT18As fit with similar quality to CT18A. Secondly, including the lattice data in the CT18As\_Lat fit greatly reduces the $s_-$-PDF error band size in the large-$x$ region. To further reduce its error would require more precise lattice data, extended to smaller $x$ values. We take ATLAS 7 TeV $W$ and $Z$ production data, SIDIS di-muon production data, $F_3$ structure function data, E866 NuSea data, and E906 SeaQuest data as examples to illustrate the implication of CT18As and CT18As\_Lat fits. The parametrization dependence for PDF ratio $(s+\bar{s})/(\bar{u}+\bar{d})(x)$ is analyzed with CT18As2 and CT18As2\_Lat fits as results.Comment: 37 pages, 19 figures. arXiv admin note: text overlap with arXiv:2204.0794

Complete genomic sequence of the temperate bacteriophage ΦAT3 isolated from Lactobacillus casei ATCC 393

AbstractThe complete genomic sequence of a temperate bacteriophage ΦAT3 isolated from Lactobacillus (Lb.) casei ATCC 393 is reported. The phage consists of a linear DNA genome of 39,166 bp, an isometric head of 53 nm in diameter, and a flexible, noncontractile tail of approximately 200 nm in length. The number of potential open reading frames on the phage genome is 53. There are 15 unpaired nucleotides at both 5′ ends of the ΦAT3 genome, indicating that the phage uses a cos-site for DNA packaging. The ΦAT3 genome was grouped into five distinct functional clusters: DNA packaging, morphogenesis, lysis, lysogenic/lytic switch, and replication. The amino acid sequences at the NH2-termini of some major proteins were determined. An in vivo integration assay for the ΦAT3 integrase (Int) protein in several lactobacilli was conducted by constructing an integration vector including ΦAT3 int and the attP (int-attP) region. It was found that ΦAT3 integrated at the tRNAArg gene locus of Lactobacillus rhamnosus HN 001, similar to that observed in its native host, Lb. casei ATCC 393

Dynamic mechanisms of tight gas accumulation and numerical simulation methods: Narrowing the gap between theory and field application

Despite the significant progress made in tight gas exploration and development in recent years, the understanding of the dynamic mechanisms of tight gas accumulation is still limited, and numerical simulation methods are lacking. In fact, the gap between theory and field application has become an obstacle to the development of tight gas exploration and development. This work sheds light on the dynamic mechanisms of hydrocarbon accumulation in tight formations from the aspect of capillary self-sealing theory by embedding calculation of pressure- and temperature-dependent capillary force in a pore network model. The microscale dynamic mechanisms are scaled up to the reservoir level by geological simulation, and the quantitative evaluation of reserves based on real geological sections is realized. From the results, several considerations are made to assist with resource assessment and sweet spot prediction. Firstly, the self-sealing effect of capillary in the micro-nano pore-throat system is at the core of tight sandstone gas accumulation theory; the hydrocarbon-generated expansion force is the driving force, and capillary force comprises the resistance. Furthermore, microscopic capillary force studies can be embedded into a pore network model and scaled up to a geological model using relative permeability curve and capillary force curve. Field application can be achieved by geological numerical simulations at the reservoir scale. Finally, high temperature and high pressure can reduce capillary pressure, which increases gas saturation and reserves.Cited as: Zhao, W., Jia, C., Song, Y., Li, X., Hou, L., Jiang, L. Dynamic mechanisms of tight gas accumulation and numerical simulation methods: Narrowing the gap between theory and field application. Advances in Geo-Energy Research, 2023, 8(3): 146-158. https://doi.org/10.46690/ager.2023.06.0

Biological Activities and Applications of Dioscorins, the Major Tuber Storage Proteins of Yam

AbstractYam tubers, a common tuber crop and an important traditional Chinese medicine in Taiwan, have many bioactive substances, including phenolic compounds, mucilage polysaccharides, steroidal saponins and proteins. Among the total soluble proteins, 80% of them are dioscorins. In the past two decades, many studies showed that dioscorins exhibited biological activities both in vitro and in vivo, including the enzymatic, antioxidant, antihypertensive, immunomodulatory, lectin activities and the protecting role on airway epithelial cells against allergens in vitro. Some of these activities are survived after chemical, heating process or enzymatic digestion. Despite of lacking the intact structural information and the detail action mechanisms in the cells, yam dioscorins are potential resources for developing as functional foods and interesting targets for food protein researchers

Generating Giant and Tunable Nonlinearity in a Macroscopic Mechanical Resonator from Chemical Bonding Force

Nonlinearity in macroscopic mechanical system plays a crucial role in a wide variety of applications, including signal transduction and processing, synchronization, and building logical devices. However, it is difficult to generate nonlinearity due to the fact that macroscopic mechanical systems follow the Hooke's law and response linearly to external force, unless strong drive is used. Here we propose and experimentally realize a record-high nonlinear response in macroscopic mechanical system by exploring the anharmonicity in deforming a single chemical bond. We then demonstrate the tunability of nonlinear response by precisely controlling the chemical bonding interaction, and realize a cubic elastic constant of \mathversion{bold}$2 \times 10^{18}~{\rm N}/{\rm m^3}$, many orders of magnitude larger in strength than reported previously. This enables us to observe vibrational bistate transitions of the resonator driven by the weak Brownian thermal noise at 6~K. This method can be flexibly applied to a variety of mechanical systems to improve nonlinear responses, and can be used, with further improvements, to explore macroscopic quantum mechanics