Ex vivo mono-ring technique simplifies culotte stenting for treatment of true bifurcation lesions: Insights from bench testing and clinical application

Background: Despite various culotte-based stenting techniques available clinically, the optimal one remains undetermined. The study aimed to test whether ex vivo mono-ring culotte stenting (MRC) was technically feasible and superior to mini culotte stenting (MCS) in treatment of coronary bifurcation lesions.Methods: Mono-ring culotte stenting was characterized by ex vivo wiring of the most proximal cell of the side branch (SB) stent to ensure a mono-ring result of the culotte stenting. Comparison of MRC vs. MCS in treatment of true bifurcation lesions was performed in vitro (n = 15 for each group) and in clinical case-controlled study with propensity matching at a ratio of 1:2 (n = 21 for MRC group; n = 42 for MCS group).Results: Compared to MCS, MRC had lower incidence of stent under-expansion band (0% vs. 53.3%, p = 0.002) and less residual ostial area stenosis of SB (9.2 ± 9.0% vs. 20.0 ± 14.8%, p = 0.023), as assessed in vitro by micro-computed tomography. In a case-controlled study, no adverse cardiac events were observed in the MRC group. The procedural success was similar between MRC and MCS (100% vs. 95.2%, p = 0.548), but MRC had less residual ostial stenosis of the SB (8.7% ± 11.0% vs. 16.8% ± 11.2%, p = 0.008), lower procedural(33.3 ± 9.5 min vs. 46.7 ± 15.6 min, p = 0.001) and fluoroscopic (19.7 ± 4.9 min vs. 26.2 ± 7.1 min, p < 0.001) time, and less contrast use (114.3 ± 28.9 mL vs. 156.5 ± 56.4 mL, p = 0.002).Conclusions: Mono-ring culotte stenting as compared to MCS is associated with better bifurcation stent morphology,less procedural complexity and residual ostial SB stenosis

A Question and Answering System for Mental Health of the Elderly Based on BiLSTM-CRF Model and Knowledge Graph

Currently, the aging population in China is becoming increasingly severe. Research has shown that 85% of the elderly have varying degrees of psychological problems, and 27% of the elderly have obvious psychological disorders such as anxiety and depression. The demand for offline and online consultation and intervention services is becoming increasingly urgent. However, there is currently a lack of systematic mental health intervention strategies targeting the elderly in relevant research and application practices. In order to explore new intervention services such as online consultation and chat with the elderly on mental health, a prototype system of question and answering for the elderly mental health has been designed, focusing on providing the elderly and related caregivers with daily psychological counseling services for the elderly. Firstly, a public mental health Q&amp;A dataset has been collected, and then the data have been manually screened to obtain mental health Q&amp;A dataset for the elderly. Based on this dataset, combined with the semantic data related to neurology for the elderly, the knowledge graph of mental health of the elderly has been constructed. Then, the problem matching module has been used to determine and analyze the types of problems faced by the elderly and generate corresponding answers to the questions. For the questions related to psychological counseling of the elderly, the BERT and BiLSTM-CRF network have been used to calculate the question template closest to the user’s question in the system, and find the corresponding answer matching the question in the knowledge graph. The experimental results show that the system can effectively understand the intention of elderly users to ask questions, and has good accuracy and reliability in answering elderly mental health related questions, which helps to address the mental health service needs of the elderly.</p

Comparative study on thermodynamical and electrochemical behavior of Al88Ni6La6 and Al86Ni6La6Cu2 amorphous alloys

Two amorphous ribbons with the compositions of Al88Ni6La6 and Al86Ni6La6Cu2 were made using the meltspun method, and their thermal response and electrochemical behavior were studied comparatively. Differential scanning calorimetry (DSC) and electrochemical polarization measurements indicated that Al86Ni6La6Cu2 exhibited slightly higher crystallization temperature (Tx), lower melting point (T1) and better corrosion resistance in 0.01 mol &middot; L&minus;1 NaCl alkaline solution. These results demonstrated that Cu (2%) addition could slightly promote the glass forming ability, but it could greatly improve the corrosion resistance of Al88Ni6La6 alloy in 0.01 mol &middot; L&minus;1 NaCl alkaline solution.<br /