A one-pot, three-component aminotriazine annulation onto 5-aminopyrazole-4-carbonitriles under microwave irradiation

A one-pot, three-component, microwave-assisted reaction of 5-aminopyrazole-4-carbonitriles, triethyl orthoformate and cyanamide afforded novel 7-arylamino-substituted 4-aminopyrazolo[1,5-a][1,3,5]triazine-8-carbonitriles. The reaction proceeded in a chemo- and regioselective manner resulting in the successful amino-1,3,5-triazine annulation onto 5-aminopyrazole-4-carbonitriles to give 4-aminopyrazolo[1,5-a][1,3,5]triazine-8-carbonitriles. The operational simplicity of the method and high purity of the products, which can be isolated via simple filtration, make this approach attractive for the preparation of a library of compounds for drug discovery processes

Wavenet based low rate speech coding

Traditional parametric coding of speech facilitates low rate but provides poor reconstruction quality because of the inadequacy of the model used. We describe how a WaveNet generative speech model can be used to generate high quality speech from the bit stream of a standard parametric coder operating at 2.4 kb/s. We compare this parametric coder with a waveform coder based on the same generative model and show that approximating the signal waveform incurs a large rate penalty. Our experiments confirm the high performance of the WaveNet based coder and show that the speech produced by the system is able to additionally perform implicit bandwidth extension and does not significantly impair recognition of the original speaker for the human listener, even when that speaker has not been used during the training of the generative model.Comment: 5 pages, 2 figure

One-pot, microwave-assisted synthesis of polymethylene-bridged bis(1H-1,2,4triazol-5(3)-amines) and their tautomerism

A highly selective and efficient method for the synthesis of 3,3’(5,5’)-polymethylene-bis(1H1,2,4-triazol-5(3)-amines) was developed using the reaction of dicarboxylic acids and aminoguanidine in an aqueous medium. This one-pot, microwave-promoted method was proved to be scalable affording the desired products in good yields and purity. The scope of the method was successfully explored by the preparation of a small library of polymethylene-bis(1H-1,2,4-triazol-5(3)-amines) with different alkyl chain linkers. The annular prototropic tautomerism in the prepared compounds was studied using NMR spectroscopy and X-ray crystallography

THE INFLUENCE OF E-SERVICE QUALITY AND BRAND IMAGE ON CUSTOMER LOYALTY THROUGH CUSTOMER SATISFACTION ON 'BIBIT' APPLICATION USERS

Currently, it is undeniable that advances in science and technology have an impact on people's lifestyles. One of them can be seen in investing activities that can be done only by having a smartphone and an internet network. Business actors use this situation to provide mutual fund investment applications. It is characterized by increasing competition between mutual fund investment applications. Increased public awareness of the importance of investment is an added value. One of the mutual fund investment applications known to be on the rise is Bibit. This study examines the effect of e-service quality and brand image on customer loyalty through customer satisfaction on users of the Bibit application. The sampling technique used is non-probability sampling with a purposive sampling type. The sample used is 150 respondents who are users of the Bibit application. The data analysis technique used is PLS-SEM with SmartPLS 3.0 program. The results showed that e-service quality and brand image each had a positive and significant effect on customer satisfaction, e-service quality and customer satisfaction each had a positive but not significant effect on customer loyalty brand image had a positive and significant effect. Customer loyalty and customer satisfaction proved unable to mediate the effect of e-service quality and brand image on customer loyalty

Low Bit-Rate Speech Coding with VQ-VAE and a WaveNet Decoder

In order to efficiently transmit and store speech signals, speech codecs create a minimally redundant representation of the input signal which is then decoded at the receiver with the best possible perceptual quality. In this work we demonstrate that a neural network architecture based on VQ-VAE with a WaveNet decoder can be used to perform very low bit-rate speech coding with high reconstruction quality. A prosody-transparent and speaker-independent model trained on the LibriSpeech corpus coding audio at 1.6 kbps exhibits perceptual quality which is around halfway between the MELP codec at 2.4 kbps and AMR-WB codec at 23.05 kbps. In addition, when training on high-quality recorded speech with the test speaker included in the training set, a model coding speech at 1.6 kbps produces output of similar perceptual quality to that generated by AMR-WB at 23.05 kbps.Comment: ICASSP 201

Investigating the influence of offline friendship on Twitter networking behaviors

Singapore National Research Foundation under its International Research Centre @ Singapore Funding Initiativ

Stabilising an Inverted Pendulum with PID Controller

Inverted pendulum is a system in which the centre of the mass is above the pivot point, where the mass can freely rotate. The inverted pendulum has a unique trait; it is unpredictable, non-linear and consists of multiple variables. Balancing by PID controller is a continuous process where it corrects the feedback system error from the difference between the measured value and the desired value. This research mainly focusses on balancing an inverted pendulum with reaction wheel. The research objectives are to construct a self-balanced inverted pendulum and using PID controller to control the stability of the pendulum. The PID configuration is then evaluated based on the response of the system. The idea is to use the reaction torque generated by the motor to counter balance the inverted pendulum. The factor which governs the amount of torque generated is the height of the pendulum and the mass of the wheel. To balance the pendulum, tuning the PID gain is essential. Proportional gain is tuned first to get oscillation, next is to tune the integral and derivative gain to get a smoother and quicker response. Idea is to get short settling time, and minimum overshoot percentage. Hypothesis is that higher proportional gain will give a faster response rate and the acceleration of the motor is the key on generating torque. A simulation of the pendulum falling is simulated and the results are recorded in term of the response of the pendulum against time. At initial point, proportional gain, integral gain and derivative gain are set to zero to validate the simulation. The finding in this research is that torque is generated by the acceleration of the reaction wheel. Higher acceleration gives a high torque. Others findings is the PID parameter; Proportional gain increases the response rate; Integral gain is used to eliminate steady state error; Derivative gain is used to lessen the overshoot.</p