6 research outputs found
Phenotypic and functional characterisation of cervical and peripheral HIV-1 specific T cell responses
Includes bibliographical references (leaves 92-109).Distinct HIV variants occur at the genital mucosa compared to in blood, which may similarly result in differences in HIV T cell responses. There have been no studies of the maturational status of HIV-specific T cells present at the female genital mucosa. This study aimed to characterise HIV-specific cervical immune responses and to determine if compartmentalized immune responses occur in chronic HIV infection by comparing the characteristics of T cells at the cervical mucosa to those in blood
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Randomized cross-sectional study to compare HIV-1 specific antibody and cytokine concentrations in female genital secretions obtained by menstrual cup and cervicovaginal lavage.
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Genital—systemic chemokine gradients and the risk of HIV acquisition in women.
CAPRISA, 2017.Abstract available in pdf
Distinct genital tract HIV-specific antibody profiles associated with Tenofovir gel.
CAPRISA, 2016.Abstract available in PDF file