4,098 research outputs found
Intersubband transitions in pseudomorphic InGaAs/GaAs/AlGaAs multiple step quantum wells
Intersubband transitions from the ground state to the first and second excited states in pseudomorphic AlGaAs/InGaAs/GaAs/AlGaAs multiple step quantum wells have been observed. The step well structure has a configuration of two AlGaAs barriers confining an InGaAs/GaAs step. Multiple step wells were grown on GaAs substrate with each InGaAs layer compressively strained. During the growth, a uniform growth condition was adopted so that inconvenient long growth interruptions and fast temperature ramps when switching the materials were eliminated. The sample was examined by cross‐sectional transmission electron microscopy, an x‐ray rocking curve technique, and the results show good crystal quality using this simple growth method. Theoretical calculations were performed to fit the intersubband absorption spectrum. The calculated energies are in good agreement with the observed peak positions for both the 1→2 and 1→3 transitions
Constraining the Skyrme effective interactions and the neutron skin thickness of nuclei using isospin diffusion data from heavy ion collisions
Recent analysis of the isospin diffusion data from heavy-ion collisions based
on an isospin- and momentum-dependent transport model with in-medium
nucleon-nucleon cross sections has led to the extraction of a value of MeV for the slope of the nuclear symmetry energy at saturation density.
This imposes stringent constraints on both the parameters in the Skyrme
effective interactions and the neutron skin thickness of heavy nuclei. Among
the 21 sets of Skyrme interactions commonly used in nuclear structure studies,
the 4 sets SIV, SV, G, and R are found to give values
that are consistent with the extracted one. Further study on the correlations
between the thickness of the neutron skin in finite nuclei and the nuclear
matter symmetry energy in the Skyrme Hartree-Fock approach leads to predicted
thickness of the neutron skin of fm for Pb, fm for Sn, and fm for Sn.Comment: 10 pages, 4 figures, 1 Table, Talk given at 1) International
Conference on Nuclear Structure Physics, Shanghai, 12-17 June, 2006; 2) 11th
China National Nuclear Structure Physics Conference, Changchun, Jilin, 13-18
July, 200
Equation of state of the hot dense matter in a multi-phase transport model
Within the framework of a multi-phase transport model, we study the equation
of state and pressure anisotropy of the hot dense matter produced in central
relativistic heavy ion collisions. Both are found to depend on the
hadronization scheme and scattering cross sections used in the model.
Furthermore, only partial thermalization is achieved in the produced matter as
a result of its fast expansion
Super-soft symmetry energy encountering non-Newtonian gravity in neutron stars
Considering the non-Newtonian gravity proposed in the grand unification
theories, we show that the stability and observed global properties of neutron
stars can not rule out the super-soft nuclear symmetry energies at
supra-saturation densities. The degree of possible violation of the
Inverse-Square-Law of gravity in neutron stars is estimated using an Equation
of State (EOS) of neutron-rich nuclear matter consistent with the available
terrestrial laboratory data.Comment: Version accepted by Physical Review Letter
A staged approach with vincristine, adriamycin, and dexamethasone followed by bortezomib, thalidomide, and dexamethasone before autologous hematopoietic stem cell transplantation in the treatment of newly diagnosed multiple myeloma
Bortezomib-based regimens have significant activities in multiple myeloma (MM). In this study, we tested the efficacy of a total therapy with a staged approach where newly diagnosed MM patients received vincristine/adriamycin/dexamethsone (VAD). VAD-sensitive patients (≥75% paraprotein reduction) received autologous hematopoietic stem cell transplantation (auto-HSCT), whereas less VAD-sensitive patients (<75% paraprotein reduction) received bortezomib/thalidomide/dexamethasone (VTD) for further cytoreduction prior to auto-HSCT. On an intention-to-treat analysis, a progressive increase of complete remission (CR) rates was observed, with cumulative CR rates of 48% after HSCT. Seven patients progressed leading to three fatalities, of which two had central nervous system disease. The 3-year overall survival and event-free survival were 75.1% and 48.3%, respectively. Six patients developed oligoclonal reconstitution with new paraproteins. In the absence of anticoagulant prophylaxis, no patients developed deep vein thrombosis. The staged application of VAD+/–VTD/auto-HSCT resulted in an appreciable response rate and promising survivals. Our approach reduced the use of bortezomib without compromising the ultimate CR rate and is of financial significance for less affluent communities
Non-Newtonian gravity in finite nuclei
In this talk, we report our recent study of constraining the non-Newtonian
gravity at femtometer scale. We incorporate the Yukawa-type non-Newtonian
gravitational potential consistently to the Skyrme functional form using the
exact treatment for the direct contribution and density-matrix expansion method
for the exchange contribution. The effects from the non-Newtonian potential on
finite nuclei properties are then studied together with a well-tested Skyrme
force. Assuming that the framework without non-Newtonian gravity can explain
the binding energies and charge radii of medium to heavy nuclei within 2%
error, we set an upper limit for the strength of the non-Newtonian
gravitational potential at femtometer scale.Comment: Talk given at the 11th International Conference on Nucleus-Nucleus
Collisions (NN2012), San Antonio, Texas, USA, May 27-June 1, 2012. To appear
in the NN2012 Proceedings in Journal of Physics: Conference Series (JPCS
Nuclear constraints on non-Newtonian gravity at femtometer scale
Effects of the non-Newtonian gravity on properties of finite nuclei are
studied by consistently incorporating both the direct and exchange contribution
of the Yukawa potential in the Hartree-Fock approach using a well-tested Skyrme
force for the strong interaction. It is shown for the first time that the
strength of the Yukawa term in the non-Newtonian gravity is limited to
within the length scale
of fm in order for the calculated properties of finite nuclei
not to be in conflict with accurate experimental data available.Comment: Additional discussions and references added; related Lab Talk is
available via http://iopscience.iop.org/0954-3899/labtalk-article/5229
Partner symmetries of the complex Monge-Ampere equation yield hyper-Kahler metrics without continuous symmetries
We extend the Mason-Newman Lax pair for the elliptic complex Monge-Amp\`ere
equation so that this equation itself emerges as an algebraic consequence. We
regard the function in the extended Lax equations as a complex potential. We
identify the real and imaginary parts of the potential, which we call partner
symmetries, with the translational and dilatational symmetry characteristics
respectively. Then we choose the dilatational symmetry characteristic as the
new unknown replacing the K\"ahler potential which directly leads to a Legendre
transformation and to a set of linear equations satisfied by a single real
potential. This enables us to construct non-invariant solutions of the Legendre
transform of the complex Monge-Amp\`ere equation and obtain hyper-K\"ahler
metrics with anti-self-dual Riemann curvature 2-form that admit no Killing
vectors.Comment: submitted to J. Phys.
Phenotypic and functional abnormalities of bone marrow-derived dendritic cells in systemic lupus erythematosus
Introduction: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by autoreactive T and B cells, which are believed to be secondary to deficient dendritic cells (DCs). However, whether DC abnormalities occur during their development in the bone marrow (BM) or in the periphery is not known.Methods: Thirteen patients with SLE and 16 normal controls were recruited. We studied the morphology, phenotype, and functional abilities of bone marrow-derived dendritic cells (BMDCs) generated by using two culture methods: FMS-like tyrosine kinase 3 (Flt3)-ligand (FL) and granulocyte-macrophage colony-stimulating factor (GM-CSF) plus interleukin-4 (IL-4), respectively.Results: BMDCs induced by FL exhibited both myeloid (mDC) and plasmacytoid DC (pDC) features, whereas GM-CSF/IL-4 induced mDC generation. Substantial phenotypic and functional defects of BMDCs were found from patients with SLE at different stages of cell maturation. When compared with healthy controls, SLE immature BM FLDCs expressed higher levels of CCR7. Both immature and mature SLE BM FLDCs expressed higher levels of CD40 and CD86 and induced stronger T-cell proliferation. SLE BM mDCs expressed higher levels of CD40 and CD86 but lower levels of HLA-DR and a lower ability to stimulate T-cell proliferation when compared with control BM mDCs.Conclusions: Our data are in accordance with previous reports that suggest that DCs have a potential pathogenic role in SLE. Defects of these cells are evident during their development in BM. BM mDCs are deficient, whereas BM pDCs, which are part of BM FLDCs, are the likely culprit in inducing autoimmunity in SLE. © 2010 Nie et al.; licensee BioMed Central Ltd.published_or_final_versio
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