THE STUDY ON SCALE AND ROTATION INVARIANT FEATURES OF THE LACUNARITY OF IMAGES

Abstract: It has been shown that the fractal dimension has a strong correlation with human judgment of surface roughness. Besides the fractal dimension, which is the most important fractal feature, lacunarity describes the characteristics of fractals. This feature is used in some fields and has good performances. In the field of image processing and recognition, it is important to study the scale and rotation invariant features. In this paper, the` scale and rotation invariant features of the Lacunarity are studied and the rule of varies is proposed

Dynamics-Based Stranded-Crowd Model for Evacuation in Building Bottlenecks

In high-density public buildings, it is difficult to evacuate. So in this paper, we propose a novel quantitative evacuation model to insure people’s safety and reduce the risk of crowding. We analyze the mechanism of arch-like clogging phenomena during evacuation and the influencing factors in emergency situations at bottleneck passages; then we design a model based on crowd dynamics and apply the model to a stadium example. The example is used to compare evacuation results of crowd density with different egress widths in stranded zones. The results show this model proposed can guide the safe and dangerous egress widths in performance design and can help evacuation routes to be selected and optimized

Can CD44+/CD24- Tumor Cells Be Used to Determine the Extent of Breast Cancer Invasion Following Neoadjuvant Chemotherapy?

breast cancers in relation to tumor size before and after the administration of neoadjuvant chemotherapy. Methods: CD44 + / CD24- tumor cells obtained from breast cancer specimens were characterized in vivo and in vitro using tumor formation assays and mammosphere generation assays, respectively. The distribution of CD44+/CD24- tumor cells in 78 breast cancer specimens following administration of neoadjuvant chemotherapy was also evaluated using immunofluorescence assays, and this distribution was compared with the extent of tumor invasion predicted by Response Evaluation Criteria in Solid Tumours (RECIST). Results: In 27/78 cases, complete remission (CR) was identified using RECIST. However, 18 of these CR cases were associated with a scattered distribution of tumor stem cells in the outline of the original tumor prior to neoadjuvant chemotherapy. After neoadjuvant chemotherapy, 24 cases involved cancer cells that were confined to the tumor outline, and 21 cases had tumor cells or tumor stem cells overlapping the tumor outline. In addition, there were 6 patients who were insensitive to chemotherapy, and in these cases, both cancer cells and stem cells were detected outside the contours of the tumor volume imaged prior to chemotherapy. Conclusion: CD44+/CD24- tumor cells may be an additional parameter to evaluate when determining the extent of breast cancer invasion. Key Words: Breast neoplasms, Neoadjuvant chemotherapy, Neoplasm invasion, Stem cell

Activity, toxicity, molecular docking, and environmental effects of three imidazolinone herbicides enantiomers

All imidazolinone (IMI) herbicides are chiral consisting of two enantiomers; however, studies on the enantioselectivities of their interactions are limited. This study is a systematic assessment of the enantiomers and racemates of IMI herbicides, including semi-preparation and determination of absolute configurations, stereoselective bioactivity toward target organisms (Echinochloa crus-galli and Microcystis aeruginosa), and toxicity toward Michigan Cancer Foundation-7 (MCF-7) cells. R-imidazolinones were found to be more active than S-IMIs in the inhibition of target organisms, and neither enantiomer had estrogenic activity. Moreover, the relationship between the molecular structures and the efficiency of target growth inhibition by the IMI herbicides was investigated. Molecular modeling provided the rational structural basis for the enantioselectivity of the acetohydroxyacid synthase (AHAS) activity of the IMIs. These findings encourage the application of enantiopure R-IMI herbicides to capitalize on their advantages over the racemates

Advances of stem cell based-therapeutic approaches for tendon repair

Tendon injuries are significant clinical problems. Current treatments often result in incomplete repair or healing, which may lead to reduced function and rupture. Stem cell-based therapy is a promising intervention for tendon repair. In this article, we attempt to provide a brief overview on the recent progress in the field, current understanding of the underlying mechanisms of the approach, and the potential of stem cell-based therapies beyond cell implantation. We conclude the review by sharing our viewpoints on the challenges, opportunities, and future directions of this approach. The translational potential of this article: This paper reviews recent progress on stem cell-based therapeutic approaches for tendon repair, which highlights its translational potential and challenges

Activity, toxicity, molecular docking, and environmental effects of three imidazolinone herbicides enantiomers

All imidazolinone (IMI) herbicides are chiral consisting of two enantiomers; however, studies on the enantioselectivities of their interactions are limited. This study is a systematic assessment of the enantiomers and racemates of IMI herbicides, including semi-preparation and determination of absolute configurations, stereoselective bioactivity toward target organisms (Echinochloa crus-galli and Microcystis aeruginosa), and toxicity toward Michigan Cancer Foundation-7 (MCF-7) cells. R-imidazolinones were found to be more active than S-IMIs in the inhibition of target organisms, and neither enantiomer had estrogenic activity. Moreover, the relationship between the molecular structures and the efficiency of target growth inhibition by the IMI herbicides was investigated. Molecular modeling provided the rational structural basis for the enantioselectivity of the acetohydroxyacid synthase (AHAS) activity of the IMIs. These findings encourage the application of enantiopure R-IMI herbicides to capitalize on their advantages over the racemates

Design of High-Precision Terahertz Filter Based on Directional Optimization Correction Method

The directional optimization correction (DOC) method is proposed to reduce the performance error between desired and fabricated terahertz (THz) devices. Three 340 GHz terahertz filters with a bandwidth of 20 GHz are designed and fabricated. The traditional global optimization correction (GOC) method and the proposed DOC method are used to optimize and reduce the performance error, respectively. It is garnered that the center frequency error and bandwidth error of the fabricated terahertz filter optimized by the GOC method are reduced to 3.5 GHz (~1.03%) and 2.2 GHz (~11%), respectively. Meanwhile, the center frequency error and bandwidth error of the fabricated terahertz filter optimized by the DOC method are reduced to 0.2 GHz (~0.06%) and 0.4 GHz (~2.0%), respectively, which has fewer optimization parameters and higher accuracy than the GOC method. Furthermore, the in-band return loss (RL) of two optimized terahertz filters based on the DOC and GOC methods is less than 15 dB, and the in-band insertion loss (IL) is less than 2.3 dB

Development of human induced pluripotent stem cell (iPSC) line from a 60 year old female patient with multiple schwannoma

Peripheral blood was collected from a clinically diagnosed 60-year old female patient with multiple schwannoma. Peripheral blood mononuclear cells (PBMCs) were reprogrammed with the Yamanaka KMOS reprogramming factors using the Sendai-virus reprogramming system. The transgene-free iPSC line showed pluripotency verified by immunofluorescent staining for pluripotency markers, and the iPSC line was able to differentiate into the 3 germ layers in vivo. The iPSC line also showed normal karyotype. This in vitro cellular model will be useful for further pathological studies of multiple schwannoma