L’abbazia di Nonantola alla luce dell’archeologia

Il monastero di Nonantola rappresenta uno dei maggiori complessi benedettini, di fondazione altomedievale, presenti sul territorio nazionale e, indubbiamente, uno dei cenobi più importanti dell’Europa medievale. Fondato nell’VIII secolo nell’orbita culturale longobarda, il monastero accrebbe i suoi possedimenti ed il suo prestigio nel tempo, arrivando a comprendere anche territori lontani (in Toscana, Lombardia e Veneto). Le indagini pluriennali condotte dall’Università Ca’ Foscari di Venezia hanno restituito una cospicua mole di materiali eterogenei che dipingono un quadro particolarmente complesso delle fasi di frequentazione che si sono succedute non solo all’interno del complesso abbaziale, ma anche dell’intero borgo di Nonantola nei secoli compresi tra l’VIII e il XV. I dati desunti dagli scavi archeologici si inseriscono, poi, in un quadro interpretativo più ampio di carattere territoriale, grazie alle indagini di ricognizione di superficie condotte su un’ampia superficie del nonantolano e dei territori limitrofi. Il nostro intervento si concentrerà sui dati relativi all’età carolingia seguendo il duplice binario della ricostruzione del complesso monastico e del rapporto con gli insediamenti presenti nel territorio circostante

The collaborative communication model for patient handover at the interface between high-acuity and low-acuity care

Background: Cross-unit handovers transfer responsibility for the patient among healthcare teams in different clinical units, with missed information, potentially placing patients at risk for adverse events. Objectives: We analysed the communications between high-acuity and low-acuity units, their content and social context, and we explored whether common conceptual ground reduced potential threats to patient safety posed by current handover practices. Methods: We monitored the communication of five content items using handover probes for 22 patient transitions of care between high-acuity ' sender units' and low-acuity 'recipient units'. Data were analysed and discussed in focus groups with healthcare professionals to acquire insights into the characteristics of the common conceptual ground. Results: High-acuity and low-acuity units agreed about the presence of alert signs in the discharge form in 40% of the cases. The focus groups identified prehandover practices, particularly for anticipatory guidance that relied extensively on verbal phone interactions that commonly did not involve all members of the healthcare team, particularly nursing. Accessibility of information in the medical records reported by the recipient units was significantly lower than reported by sender units. Common ground to enable interpretation of the complete handover content items existed only among selected members of the healthcare team. Conclusions: The limited common ground reduced the likelihood of correct interpretation of important handover information, which may contribute to adverse events. Collaborative design and use of a shared set of handover content items may assist in creating common ground to enable clinical teams to communicate effectively to help increase the reliability and safety of cross-unit handovers

Association Between Increased Platelet P-Selectin Expression and Obesity in Patients With Type 2 Diabetes: A BARI 2D (Bypass Angioplasty Revascularization Investigation 2 Diabetes) substudy

OBJECTIVE- To determine whether obesity increases platelet reactivity and thrombin activity in patients with type 2 diabetes plus stable coronary artery disease. RESEARCH DESIGN AND METHODS- We assessed platelet reactivity and markers of thrombin generation and activity in 193 patients from nine clinical sites of the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D). Blood taken at the time of enrollment was used for assay of the concentration of prothrombin fragment 1.2 (PT1.2, released when prothrombin is activated) and fibrinopeptide A (FPA, released when fibrinogen is cleaved). Platelet activation was identified with the use of flow cytometry in response to 0, 0.2, and 1 mu mol/l adenosine diphosphate (ADP). RESULTS- Concentrations of FPA, PT1.2, and platelet activation in the absence of agonist were low. Greater BMI was associated with higher platelet reactivity in response to 1 mu m ADP as assessed by surface expression of P-selectin (r = 0.29, P < 0.0001) but not reflected by the binding of fibrinogen to activated glycoprotein IIb-IIIa. BMI was not associated with concentrations of FPA or PT1.2. Platelet reactivity correlated negatively with A1C (P < 0.04), was not related to the concentration Of triglycerides in blood, and did not correlate with the concentration of C-reactive peptide. CONCLUSIONS- Among patients enrolled in this substudy of BARI 2D, a greater BMI was associated with higher platelet reactivity at the time of enrollment. Our results suggest that obesity and insulin resistance that accompanies obesity may influence platelet reactivity in patients with type 2 diabetes.National Heart, Lung, and Blood Institute (NHLBI/NIH)[R01 HL69146]National Heart, Lung, and Blood Institute (NHLBI/NIH)[R01 HL71306]NHLBI[U01 HL061746]NHLBI[U01 HL06171748]NHLBI[U01 HL06384]National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK/NIH)[HL061744

Nonantola. L'abbazia e le sue chiese

Si tratta del IV volume di una serie dedicata alle ricerche archeologiche che l'Insegnamento di Archeologia Medievale dell'Università Ca' Foscari ha condotto nell'area dell'abbazia benedettina di Nonantola. Questo volume contiene una serie di saggi miscellanei dedicati all'analisi della chiesa abbaziale e della chiesa pievana di San Michele (studio degli alzati, elementi di reimpiego, scavo